Protein inspired chemically orthogonal imines for linchpin directed precise and modular labeling of lysine in proteins

2022 ◽  
Author(s):  
Tularam Sahu ◽  
Maheshwerreddy Chilamari ◽  
Vishal Rai
Keyword(s):  
Precision Engineering ◽  
Large Pool

The chemical technologies for the precision engineering of proteins connect chemistry, biology, and medicine. However, they face enormous hurdles due to a large pool of competing proteinogenic residues. While resolving...

Präzisions-Forstwirtschaft – was ist das? | Precision forestry – what's that?

2007 ◽  
Vol 158 (8) ◽  
pp. 235-242 ◽  
Author(s):  
Hans Rudolf Heinimann
Keyword(s):  
Business Processes ◽  
Spatial Scales ◽  
Supply Chain Coordination ◽  
Sensor Technology ◽  
Small Scale ◽  
Soil Physics ◽  
Coordination Problem ◽  
Precision Engineering ◽  
Precision Forestry ◽  
And Control

The term «precision forestry» was first introduced and discussed at a conference in 2001. The aims of this paper are to explore the scientific roots of the precision concept, define «precision forestry», and sketch the challenges that the implementation of this new concept may present to practitioners, educators, and researchers. The term «precision» does not mean accuracy on a small scale, but instead refers to the concurrent coordination and control of processes at spatial scales between 1 m and 100 km. Precision strives for an automatic control of processes. Precision land use differs from precision engineering by the requirements of gathering,storing and managing spatio-temporal variability of site and vegetation parameters. Practitioners will be facing the challenge of designing holistic, standardized business processes that are valid for whole networks of firms,and that follow available standards (e.g., SCOR, WoodX). There is a need to educate and train forestry professionals in the areas of business process re-engineering, computer supported management of business transactions,methods of remote sensing, sensor technology and control theory. Researchers will face the challenge of integrating plant physiology, soil physics and production sciences and solving the supply chain coordination problem (SCCP).

Human Resource Practices in the Non-Star Category Hotels in Kolkata

2015 ◽  
Vol 8 (1and2) ◽  
Author(s):  
P. R. Sandilyan ◽  
Sutheeshana Babu S.
Keyword(s):  
Empirical Study ◽  
Work Environment ◽  
Human Resource ◽  
Minimum Wages ◽  
Human Resource Practices ◽  
Human Resource Managers ◽  
Large Pool ◽  
Resource Managers ◽  
Safety Work ◽  
The City

In this empirical study, the authors made an attempt to examine the challenges faced by the human resource managers and employees as well as the benefits extended to the employees in the non-star hotel segment in the city of Kolkata It was also endeavored to ascertain the standards maintained by these hotels specifically the hygiene, safety, work environment and to mandatory legal and regulatory compliances. The results show that while these hotels were profitable and enjoyed a healthy market, the human resource practices were unhealthy and discriminatory in nature. Employees were neither provided with minimum wages and benefits nor have the establishments shown any interest in adhering to the mandatory compliances. This could largely be attributed to predominance of largely unskilled or inadequately qualified employees and a large pool of outsourced manpower.

Key Technologies of the Embedded Deformation Measuring Control System Based on SOPC

2014 ◽  
Vol 644-650 ◽  
pp. 773-776
Author(s):  
Qiu Hong Song
Keyword(s):  
Deformation Measurement ◽  
Control Mode ◽  
Precision Engineering ◽  
Automatic Data ◽  
Industrial Buildings ◽  
The Status ◽  
Rock Mass Deformation ◽  
Crust Deformation ◽  
Measuring Control ◽  
Automatic Data Acquisition

Deformation measurement is an important content of engineering surveying and the main objects of the deformation measurement are civilians, industrial buildings, precision engineering, large dam, bridge and the earth's crust deformation of rock mass. Deformation measurement aims to obtain the deformation data in the process of displacement deformation, and to get the deformation of the status, trend and possible results through the analysis of these data. The existing automatable solution for measuring the deformation all adopt the 3-dimension displacement test, which based on high precision total station, unattended, automatic data acquisition and transmission control mode.

An Analytical Comparison Between Ball and Crossed Roller Bearings for Utilization in Actuator Modules for Precision Modular Robots

2003 ◽  
Author(s):  
Seong-Ho Kang ◽  
Delbert Tesar
Keyword(s):  
High Performance ◽  
Background Information ◽  
Modular Robots ◽  
Extensive Literature ◽  
Positional Accuracy ◽  
Precision Engineering ◽  
Friction Cost ◽  
Low Weight ◽  
Bearing Stiffness ◽  
Robot Configurations

A modular robot system is a collection of actuators, links, and connections that can be arbitrarily assembled into a number of different robot configurations and sequences. High performance modular robots require more than just sophisticated controls. They also need top-quality mechanical components. Bearings in particular must operate well at low speed, have high rotational accuracy, be compact for low weight, and especially be stiff for high positional accuracy. To ensure the successful use of bearings in precision modular robots, knowledge of the bearing properties and requirements are investigated. Background information on various topics such as modular robots, precision modular actuators, and their error sources are described with respect to precision engineering. Extensive literature on thin section bearings is reviewed to examine their use in precision robotic applications. Theoretical studies are performed to calculate bearing stiffness adopting a methodology based on Hertzian theory. This approach is applied to analyze two proposed designs of equivalent-sized crossed roller and four-point bearings, principal bearings used for transmitting all the payload and mass of the robot structure. The maximum deflections and contact stresses for the proposed actuator assembly and loading conditions are estimated and compared including a range of general bearing properties such as friction, cost, and shock resistance.

Measles in the Future?

PEDIATRICS ◽  
1983 ◽  
Vol 71 (3) ◽  
pp. 465-465
Author(s):  
C. E. HEALY ◽  
WELBORN CLINIC
Keyword(s):  
Failure Rate ◽  
Hemagglutination Inhibition ◽  
Neutralizing Antibodies ◽  
Immunization Practice ◽  
Large Pool ◽  
The Future

To the Editor.— I am concerned about measles immunization in that most studies show up to a 5% failure rate with the current immunization practice, at least as measured by the hemagglutination-inhibition (HI) technique. Some of these children might be protected by neutralizing antibodies or cellular (lymphocytic)-mediated immunity, but the extent and duration of this immunity, if any, is unknown. HI immunity is apparently permanent. The end result of the current immunization practice will be a large pool of hundreds of thousands and eventually, millions of adults, who will be susceptible to measles.

NUTRITION, GROWTH AND NEUROINTEGRATIVE DEVELOPMENT: AN EXPERIMENTAL AND ECOLOGIC STUDY

PEDIATRICS ◽  
1966 ◽  
Vol 38 (2) ◽  
pp. 319-320 ◽  
Author(s):  
Joaquin Cravioto ◽  
Elsa R. DeLicardie ◽  
Herbert G. Birch
Keyword(s):  
Nervous System ◽  
Animal Experiments ◽  
Ecologic Study ◽  
Large Pool ◽  
Environmental Responsiveness ◽  
Social Custom ◽  
The Central Nervous System ◽  
Physical Stature ◽  
Inadequate Food Intake ◽  
Normal Controls

IN THIS MONOGRAPH we report the results of an experimental and ecologic study concerned with estimating some of the effects which malnutrition in early childhood may have upon neurointegrative functioning. In particular, we have been concerned with the association between malnutrition early in childhood and intersensory organization in children during the school years. A study of these relationships has derived from a concern with the possibility that inadequate food intake, particularly as represented by protein-calorie malnutrition, affects not only stature and weight, but also the capacity to learn. If this is indeed the case, then the significance of the observable and dramatic consequences of malnutrition for physical stature may be but one visible sign of functionally, perhaps, far more important non-visible handicapping. Findings on the effects which malnutrition has on the central nervous system suggest strongly that protein deficiency may result in structural lesions of the nervous system. Animals experimentally deprived are persistently delayed in achieving simple developmental landmarks, appear to be less adequate in environmental responsiveness and slower in learning as well as poorer in the retention of that which has been learned than normal controls. Considering the animal experiments and the findings in humans as a unit, one is led to be concerned with what in an ecologic sense could be called a "spiral" effect. A low level of adaptive capacity, ignorance, social custom, infection, or environmental paucity of foodstuffs appear to result in malnutrition which may produce a large pool of individuals who come to function in suboptimal ways.

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