Intramolecular H-bond Stabilization of a Primary Hydroxylamine in Salen-Type Metal Complexes

2021 ◽  
Author(s):  
Hardeep Singh ◽  
Alyson MacKay ◽  
Nooshin Sheibany ◽  
Fei Chen ◽  
Maëlle Mosser ◽  
...  
Keyword(s):  
Hydrogen Bond ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Intramolecular Hydrogen Bond ◽  
Ligand Design ◽  
Transition Metal Ions ◽  
Intramolecular Hydrogen

Primary hydroxylamines, RNHOH, decompose readily in the presence of transition metal ions. We show that this reactivity can be arrested by ligand design via an intramolecular hydrogen bond. Six metal...

Synthesis, Characterization and in vitro Biological Evaluation of a New Schiff Base Derived from Drug and its Complexes with Transition Metal Ions

2018 ◽  
Vol 69 (7) ◽  
pp. 1678-1681
Author(s):  
Amina Mumtaz ◽  
Tariq Mahmud ◽  
M. R. J. Elsegood ◽  
G. W. Weaver
Keyword(s):  
Schiff Base ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Complexes ◽  
Free Ligand ◽  
Transition Metal Ions ◽  
Biological Evaluation ◽  
Pyridoxal Hydrochloride

New series of copper (II), cobalt (II), zinc (II), nickel (II), manganese (II), iron (II) complexes of a novel Schiff base were prepared by the condensation of sulphadizine and pyridoxal hydrochloride. The ligand and metal complexes were characterized by utilizing different instrumental procedures like microanalysis, thermogravimetric examination and spectroscopy. The integrated ligand and transition metal complexes were screened against various bacteria and fungus. The studies demonstrated the enhanced activity of metal complexes against reported microbes when compared with free ligand.

scholarly journals The proton and metal complexes of adenyl-5′-yl imidodiphosphate

1976 ◽  
Vol 159 (1) ◽  
pp. 169-171 ◽  
Author(s):  
L D Pettit ◽  
K F Siddiqui
Keyword(s):  
Complex Formation ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
Transition Metal Ions ◽  
Formation Constants ◽  
Enthalpy Change ◽  
Two Temperatures ◽  
Bivalent Transition Metal

The formation constants of the complexes of adenyl-5′-yl imidodiphosphate with H+ Mg2+, Ca2+ and a number of bivalent transition-metal ions were measured potentionmetrically. The complexes are generally a little more stable than the analogous complexes of ATP. By measuring the formation constants at two temperatures, this increase in stability was shown to result from an increased enthalpy change on complex-formation.

scholarly journals Synthesis, Characterization, Molecular Docking and Enzyme Inhibition Studies of Some Novel Enaminone Derivatives and Their Complexes with Cu(II), Cd(II) and Co(II) Ions

2019 ◽  
Vol 70 (10) ◽  
pp. 3564-3569
Author(s):  
Rahila Huma ◽  
Tariq Mahmud ◽  
Liviu Mitu ◽  
Muhammad Ashraf ◽  
Ambar Iqbal ◽  
...  
Keyword(s):  
Molecular Docking ◽  
Transition Metal ◽  
Metal Ions ◽  
Metal Complexes ◽  
1H Nmr ◽  
13C Nmr ◽  
Transition Metal Ions ◽  
Binding Mode ◽  
Inhibitory Activities ◽  
Inhibition Studies

Two new enaminone ligands, 3-chloro-4-{(4-chlorophenyl)amino}pent-3-en-2-one (Ac-PCA), 4-(benzylamino)-3-chloropent-3-en-2-one (Ac-BA) and their metal complexes with transition metal ions [Cu(II), Cd(II) and Co(II)] were prepared and subsequently characterized by FTIR, ICP-AES, UV-Vis, TGA, 1H NMR, 13C NMR and FAB-MS. These newly synthesized compounds were further investigated for anti-acetylcholinesterase (AChE) and anti-urease activities. The (Ac-BA)Cu(II) complex exhibited good anti-AChE while (Ac-BA)2Co(II) complex was potent against anti-urease activities. Other ligands and complexes showed poor to no enzyme inhibitory activities. The synthesized compounds were docked inside acetylcholinesterase enzymes to determine their putative binding mode.

scholarly journals Crystal structure of N-(diphenylphosphoryl)-2-methoxybenzamide

2019 ◽  
Vol 75 (7) ◽  
pp. 939-941
Author(s):  
Victor A. Trush ◽  
Nataliia S. Kariaka ◽  
Viktoriya V. Dyakonenko ◽  
Svitlana V. Shishkina ◽  
Vladimir M. Amirkhanov
Keyword(s):  
Crystal Structure ◽  
Hydrogen Bond ◽  
Metal Ions ◽  
Intermolecular Interactions ◽  
Intramolecular Hydrogen Bond ◽  
Title Compound ◽  
Π Interactions ◽  
Compound C ◽  
Bidentate Chelate ◽  
Intramolecular Hydrogen

In the title compound, C20H18NO3P, the C=O and P=O groups of the carbacylamidophosphate (CAPh) fragments are located in a synclinal position relative to each other and are pre-organized for bidentate chelate coordination of metal ions. The N—H group is involved in the formation of an intramolecular hydrogen bond. In the crystal, molecules do not form strong intermolecular interactions but the molecules are linked via weak C—H...π interactions, forming chains along [001].

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