Facile Synthesis of Tribenzosilepins from Terphenyls and Dihydrosilanes by Electrophilic Double Silylation

2021 ◽  
Author(s):  
Yafang Dong ◽  
Kohei Sekine ◽  
Yoichiro Kuninobu
Keyword(s):  
Reaction System ◽  
High Yield ◽  
Facile Synthesis

Tribenzosilepins were synthesized from terphenyls and dihydrosilanes using a facile approach using a double sila-Friedel–Crafts reaction. Several silepin derivatives were obtained in moderate to high yield. The reaction system was...

Facile Synthesis of a Diverse Library of Mono-3-substituted β-Cyclodextrin Analogues

2018 ◽  
Author(s):  
Kathryn Kellett ◽  
Brendan M. Duggan ◽  
Michael Gilson
Keyword(s):  
High Yield ◽  
Facile Synthesis ◽  
Wide Range

We have described simple, high-yield, protocols, which require only commonly accessible equipment, to synthesize a wide range of β-CD derivatives mono-substituted at the secondary face. These derivatives may be useful in their own right, and they are also scaffolds for further modification, and examples of the far broader array of derivatives that may be accessed by these procedures.

Polymer-Bound Triphenylphosphine and 4,4′-Dinitroazobenzene as a Coupling Reagents for Chromatography-Free Esterification Reaction

2019 ◽  
Vol 16 (7) ◽  
pp. 1024-1031
Author(s):  
Diparjun Das ◽  
Kalyani Rajkumari ◽  
Lalthazuala Rokhum
Keyword(s):  
Microwave Irradiation ◽  
Solid Phase ◽  
Reaction System ◽  
Triphenylphosphine Oxide ◽  
High Yield ◽  
Sustainable Chemistry ◽  
Esterification Reaction ◽  
Coupling Reagent ◽  
Simple Filtration ◽  
Esterification Reactions

Aim and Objective: Sustainable production of fine chemicals both in industries and pharmaceuticals heavily depends on the application of solid-phase synthesis route coupled with microwave technologies due to their environmentally benign nature. In this report, a microwave-assisted esterification reaction using polymer-bound triphenylphosphine and 4,4′-dinitroazobenzene reagent system was investigated. Materials and Methods: The solvents were obtained from Merck India. Polymer-bound triphenylphosphine (~3 mmol triphenylphosphine moiety/g) was acquired from Sigma-Aldrich. The progress of the reaction was observed by thin-layer chromatography. All the reactions were performed in Milestones StartSYNTH microwave. The NMR spectra were recorded on Bruker Avance III 300, 400, and 500 MHz FT NMR Spectrometers. Using azo compound and polymer-bound triphenyl phosphine as a coupling reagent, esterification of different carboxylic acids with alcohols was performed under microwave irradiation. Results: Esterification of benzoic acid with 1-propanol under microwave irradiation gave a high yield of 92% propyl benzoate in 60 minutes only. Isolation of the ester products was relatively simple as both the byproducts polymer-bound triphenylphosphine oxide and hydrazine could be removed by simple filtration. The rates of reactions were found to be directly proportional to the pKa of the benzoic acids. Conclusion: 4,4′-Dinitroazobenzene was introduced as a novel coupling reagent, in conjugation with polymer-bound triphenylphosphine, for esterification reactions under microwave irradiation. The low moisture sensitivity of the reaction system, easy separation of the byproducts, and column chromatographyfree isolation of esters help our methods with application significance, particularly from the ‘Sustainable Chemistry’ perspective.

Eco-Friendly Synthesis of Sulphonic Acid Oxime Esters Catalyzed by 2-(1H-Benzotriazole-1-yl)-1,1,3,3-Tetramethyluronium Tetrafluoroborate

2014 ◽  
Vol 525 ◽  
pp. 93-96
Author(s):  
Wei Shi ◽  
Ji Ming Zhang ◽  
Jian Hua Zhou ◽  
Jian Hua Zhou ◽  
Song Song Ding
Keyword(s):  
High Selectivity ◽  
Sulphonic Acid ◽  
Present Approach ◽  
High Yield ◽  
Facile Synthesis ◽  
Reaction Duration ◽  
Mild Conditions ◽  
Environmental Friendly

Herein we describle a facile synthesis of sulphonic acid oxime esters in acetonitrile from the corresponding sulphonic acids and oximes catalyzed by the environmental friendly 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethyluronium tetrafluoroborate (TBTU) in the presence of triethylamine (TEA) under mild conditions. The present approach offers the advantages of a clean reaction, simple methodology, employing readily available catalyst, short reaction duration, high selectivity and high yield.

A two-phase system for the clean and high yield synthesis of furylmethane derivatives over –SO3H functionalized ionic liquids

2017 ◽  
Vol 19 (20) ◽  
pp. 4804-4810 ◽  
Author(s):  
S. H. Shinde ◽  
C. V. Rode
Keyword(s):  
Ionic Liquids ◽  
Reaction System ◽  
High Yield ◽  
Phase System ◽  
Phase Reaction ◽  
Two Phase ◽  
Yield Production ◽  
High Yield Production

A new and effective unique two-phase reaction system for the high yield production of tri(furyl)methane from furfural and furan.

Cancer theranosis using mono-disperse, mesoporous gold nanoparticles obtained via a robust, high-yield synthetic methodology

RSC Advances ◽  
2016 ◽  
Vol 6 (16) ◽  
pp. 13554-13561 ◽  
Author(s):  
Taeksu Lee ◽  
Doyeon Bang ◽  
Yong Wook Chang ◽  
Yuna Choi ◽  
Kwang Yeol Park ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
High Yield ◽  
Synthetic Methodology ◽  
Facile Synthesis ◽  
Potential Applications

Here, we introduce the facile synthesis of scalable, mono-disperse, mesoporous gold nanoparticles (MPGNs) with an acidic emulsification method, which exhibit many attractive nanoplasmonic features for potential applications in many fields.

Facile synthesis of furfuryl ethyl ether in high yield via the reductive etherification of furfural in ethanol over Pd/C under mild conditions

2018 ◽  
Vol 20 (9) ◽  
pp. 2110-2117 ◽  
Author(s):  
Yun Wang ◽  
Qianqian Cui ◽  
Yejun Guan ◽  
Peng Wu
Keyword(s):  
Ethyl Ether ◽  
High Yield ◽  
Facile Synthesis ◽  
Mild Conditions

Furfuryl ethyl ether (FEE) was synthesized from furfural via reductive etherification in 81% yield over a Pd/C catalyst under mild conditions.

scholarly journals Facile synthesis of high yield two dimensional zinc vanadate nanoflakes

2019 ◽  
Vol 1 (5) ◽  
Author(s):  
Sawsan A. Mahmoud ◽  
Samar H. Bendary ◽  
A. A. Salem ◽  
Osama A. Fouad
Keyword(s):  
High Yield ◽  
Two Dimensional ◽  
Facile Synthesis

Preparation of Two Novel Ionic Electroconductive Polyurethanes Functionalized with the Backbone of Ionic Liquid

2013 ◽  
Vol 668 ◽  
pp. 259-262
Author(s):  
Ding Jun Zhang ◽  
Chao Yun Qu ◽  
Yu Xian Chen
Keyword(s):  
Electrical Conductivity ◽  
Differential Scanning Calorimetry ◽  
Ionic Liquid ◽  
Surface Resistance ◽  
High Yield ◽  
Gravimetric Analysis ◽  
Thermal Gravimetric ◽  
Facile Synthesis ◽  
Scanning Calorimetry ◽  
Structures And Properties

The facile synthesis of two new Ionic electroconductive polyurethanes with the framework of ionic liquids, i.e., PUR-T: synthesized with isocyanate TDI; PUR-H: synthesized with isocyanate HDL, are described. Their structures and properties were characterized by Fourier transform infrared spectroscopy (FTIR), thermal gravimetric analysis (TGA), Differential scanning calorimetry (DSC) and the surface resistance meter. The effects of the different kinds of isocyanate on electrical conductivity of PUR were also investigated. It was found that their electrical conductivity can be optimized by changing the reaction temperature. The PUR-H, which exhibits an electrical conductivity of 1.0×104 Ω surface resistance, could be obtained in high yield, up to 65% at 90 oC for 12h.

scholarly journals Facile synthesis of novel hybrid POSS biomolecules via “Click” reactions

RSC Advances ◽  
2017 ◽  
Vol 7 (59) ◽  
pp. 37474-37477 ◽  
Author(s):  
Youssef El Aziz ◽  
Nazia Mehrban ◽  
Peter G. Taylor ◽  
Martin A. Birchall ◽  
James Bowen ◽  
...  
Keyword(s):  
Click Chemistry ◽  
High Yield ◽  
Facile Synthesis ◽  
Click Reactions

A novel alkyne-terminated cubic-octameric POSS was synthesised in high yield and click chemistry has been used to attach bio-oligomers.

High Yield Synthesis of Kojic Ester Using Dual Enzymes System and their Antibacterial Activity

2013 ◽  
Vol 594-595 ◽  
pp. 362-369 ◽  
Author(s):  
Salina Mat Radzi ◽  
Nurul Jannah Abd Rahman ◽  
Hanina Mohd Noor ◽  
Mahiran Basri
Keyword(s):  
Reaction Time ◽  
Inhibitory Concentration ◽  
Minimum Bactericidal Concentration ◽  
Reaction System ◽  
Bactericidal Effect ◽  
High Yield ◽  
Esterification Reaction ◽  
Optimum Conditions ◽  
Whitening Agent ◽  
Immobilized Lipases

Enzymatic synthesis of kojic ester, a bio-based whitening agent, was successfully carried out via esterification reaction between oleic acid and kojic acid. Commercial immobilized lipases of Novozym 435 and Lipozyme RM IM were used in combination as biocatalyst in the reaction system. Various reaction parameters were chosen to optimize the reaction in order to obtain a high yield of kojic ester including the best ratio of lipases, reaction time and reaction temperature. The optimum conditions for the synthesis of kojic ester was achieved at reaction time of 12 hours, temperature of 60 οC and equal ratio of lipases to produce more than 70 % yield. Antimicrobial tests of synthesized kojic ester towards several types of bacteria via Minimum inhibitory concentration (MIC) and Minimum bactericidal concentration (MBC) analyses were also examined. The results obtained suggested that kojic ester exhibits a good bactericidal effect towards all bacteria tested such as Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Salmonella typhimurium.

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