Palladium-Catalyzed Cascade Carbonylative Annulation between Alkene-tethered Aryl Iodides and Carbon Monoxide

2021 ◽  
Author(s):  
Yong Zhang ◽  
Ya-Kui Sun ◽  
Ya-Ping Chang ◽  
Hui Shao ◽  
Yu-Ming Zhao
Keyword(s):  
Carbon Monoxide ◽  
Organic Synthesis ◽  
Aryl Iodides ◽  
Rapid Construction ◽  
Palladium Catalyzed ◽  
Quaternary Stereocenters

Rapid construction of molecules bearing all-substituted quaternary stereocenters represents a highly significant but challenging task in organic synthesis. Herein, we report a novel Palladium-catalyzed cascade between alkene-tethered aryl iodides and...

scholarly journals Palladium-Catalyzed Reaction of Aryl Iodides with Acetic Anhydride. A Carbon Monoxide Free Synthesis of Acetophenones.

ChemInform ◽  
2003 ◽  
Vol 34 (24) ◽  
Author(s):  
Sandro Cacchi ◽  
Giancarlo Fabrizi ◽  
Federica Gavazza ◽  
Antonella Goggiamani
Keyword(s):  
Carbon Monoxide ◽  
Acetic Anhydride ◽  
Aryl Iodides ◽  
Palladium Catalyzed

Recyclable Heterogeneous Palladium-Catalyzed Carbonylative Cyclization of 2-Iodoanilines with Aryl Iodides Leading to 2-Arylbenzoxazinones

Synthesis ◽  
2019 ◽  
Vol 52 (04) ◽  
pp. 581-590 ◽  
Author(s):  
Zhaotao Xu ◽  
Bin Huang ◽  
Zebiao Zhou ◽  
Mingzhong Cai
Keyword(s):  
Carbon Monoxide ◽  
Palladium Catalyst ◽  
Functional Group ◽  
Atom Economy ◽  
Highly Efficient ◽  
Aryl Iodides ◽  
Palladium Catalyzed ◽  
High Yields

A highly efficient and practical heterogeneous palladium-catalyzed carbonylative coupling of 2-iodoanilines with aryl iodides has been developed. The reaction occurs smoothly in toluene at 110 °C with N,N-diisopropylethylamine as base under carbon monoxide (5 bar) and offers a general and powerful tool for the construction of various valuable 2-arylbenzoxazinones with excellent atom-economy, high functional group tolerance, good to high yields, and easy recyclability of the palladium catalyst. The reaction is the first example of heterogeneous palladium-catalyzed carbonylative coupling for the preparation of diverse 2-arylbenzoxazinones from commercially easily available 2-iodoanilines and aryl iodides.

scholarly journals A palladium-catalyzed synthesis of (hetero)aryl-substituted imidazoles from aryl halides, imines and carbon monoxide

2017 ◽  
Vol 8 (2) ◽  
pp. 1002-1007 ◽  
Author(s):  
Jevgenijs Tjutrins ◽  
Bruce A. Arndtsen
Keyword(s):  
Carbon Monoxide ◽  
Aryl Halides ◽  
Single Operation ◽  
Aryl Iodides ◽  
Palladium Catalyzed

We describe here a tandem catalytic route to prepare imidazoles in a single operation from aryl iodides, imines and CO.

Palladium-Catalyzed Reaction of Aryl Iodides with Acetic Anhydride. A Carbon Monoxide-Free Synthesis of Acetophenones

2003 ◽  
Vol 5 (3) ◽  
pp. 289-291 ◽  
Author(s):  
Sandro Cacchi ◽  
Giancarlo Fabrizi ◽  
Federica Gavazza ◽  
Antonella Goggiamani
Keyword(s):  
Carbon Monoxide ◽  
Acetic Anhydride ◽  
Aryl Iodides ◽  
Palladium Catalyzed

Synthesis of diversely substituted 2-(furan-3-yl)acetates from allenols through cascade carbonylations

2015 ◽  
Vol 51 (90) ◽  
pp. 16263-16266 ◽  
Author(s):  
Yan He ◽  
Xinying Zhang ◽  
Xuesen Fan
Keyword(s):  
Carbon Monoxide ◽  
One Pot ◽  
Novel Synthesis ◽  
Aryl Iodides ◽  
Palladium Catalyzed

Novel synthesis of diversely substituted 2-(furan-3-yl)acetatesviapalladium-catalyzed one-pot multi-component reactions of allenols, aryl iodides, alcohols, and carbon monoxide has been developed. Moreover, the 2-(furan-3-yl)acetates obtained were found to be ready intermediates for the construction of the biologically significant naphtho[1,2-b]furan-5-ol scaffold.

Sign in / Sign up

Export Citation Format

Share Document