Synthesis of diversely substituted 2-(furan-3-yl)acetates from allenols through cascade carbonylations
Novel synthesis of diversely substituted 2-(furan-3-yl)acetatesviapalladium-catalyzed one-pot multi-component reactions of allenols, aryl iodides, alcohols, and carbon monoxide has been developed. Moreover, the 2-(furan-3-yl)acetates obtained were found to be ready intermediates for the construction of the biologically significant naphtho[1,2-b]furan-5-ol scaffold.
Palladium-Catalyzed Reaction of Aryl Iodides with Acetic Anhydride. A Carbon Monoxide Free Synthesis of Acetophenones.