A Multifunctional Supramolecular Hydrogel for Infected Wound Healing

2021 ◽  
Author(s):  
Tingting Ding ◽  
Jiajia Qi ◽  
Jingcheng Zou ◽  
Hongxia Dan ◽  
Hang Zhao ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Wound Dressings ◽  
Infected Wound ◽  
Supramolecular Hydrogel ◽  
Physical Barriers

Bacterial infection poses a significant threat to wound healing, and the preparation of novel wound dressings is a concern. However, currently reported dressings serve as traditional physical barriers or functioned...

Muscle-inspired MXene/PVA hydrogel with high toughness and photothermal therapy for promoting bacteria-infected wound healing

2022 ◽  
Author(s):  
Yan Li ◽  
Miao-miao Han ◽  
Yue Cai ◽  
Bing Jiang ◽  
Yuanxin Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Human Health ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Traditional Therapy ◽  
High Toughness ◽  
Pva Hydrogel

The process of wound healing is often accompanied by bacterial infection, which is a serious threat to human health. The abuse of antibiotics in traditional therapy aggravates the resistance of...

The in situ synthesis of Ag/amino acid biopolymer hydrogels as mouldable wound dressings

2015 ◽  
Vol 51 (87) ◽  
pp. 15862-15865 ◽  
Author(s):  
Zhenzhu Zhang ◽  
Ting He ◽  
Mengying Yuan ◽  
Rujuan Shen ◽  
Liu Deng ◽  
...  
Keyword(s):  
Wound Healing ◽  
Amino Acid ◽  
In Situ Synthesis ◽  
Wound Dressings ◽  
Supramolecular Hydrogel ◽  
Green Strategy

Monodispersed AgNPs were in situ fabricated in a hybrid supramolecular hydrogel via a green strategy. The as-prepared nanocomposite has been proved to be a mouldable wound healing biomaterial.

scholarly journals A graphene hybrid supramolecular hydrogel with high stretchability, self-healable and photothermally responsive properties for wound healing

RSC Advances ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 6367-6373
Author(s):  
Haifeng Zhang ◽  
Shiya Zheng ◽  
Canwen Chen ◽  
Dagan Zhang
Keyword(s):  
Wound Healing ◽  
Photothermal Therapy ◽  
Infected Wound ◽  
Supramolecular Hydrogel

The hydrogel demonstrated properties with high stretchability, self-healable and photothermal properties. Notably, photothermal therapy could be established due to its photothermal responsiveness, benefiting infected wound healing.

scholarly journals Fabrication of Hybrid Nanofibers from Biopolymers and Poly (Vinyl Alcohol)/Poly (ε-Caprolactone) for Wound Dressing Applications

Polymers ◽  
2021 ◽  
Vol 13 (13) ◽  
pp. 2104
Author(s):  
Sibusiso Alven ◽  
Blessing Atim Aderibigbe
Keyword(s):  
Mechanical Properties ◽  
Wound Healing ◽  
Vinyl Alcohol ◽  
Wound Dressing ◽  
Chronic Wounds ◽  
Cellular Adhesion ◽  
Wound Dressings ◽  
Poly Vinyl Alcohol ◽  
High Porosity ◽  
Hybrid Nanofibers

The management of chronic wounds is challenging. The factors that impede wound healing include malnutrition, diseases (such as diabetes, cancer), and bacterial infection. Most of the presently utilized wound dressing materials suffer from severe limitations, including poor antibacterial and mechanical properties. Wound dressings formulated from the combination of biopolymers and synthetic polymers (i.e., poly (vinyl alcohol) or poly (ε-caprolactone) display interesting properties, including good biocompatibility, improved biodegradation, good mechanical properties and antimicrobial effects, promote tissue regeneration, etc. Formulation of these wound dressings via electrospinning technique is cost-effective, useful for uniform and continuous nanofibers with controllable pore structure, high porosity, excellent swelling capacity, good gaseous exchange, excellent cellular adhesion, and show a good capability to provide moisture and warmth environment for the accelerated wound healing process. Based on the above-mentioned outstanding properties of nanofibers and the unique properties of hybrid wound dressings prepared from poly (vinyl alcohol) and poly (ε-caprolactone), this review reports the in vitro and in vivo outcomes of the reported hybrid nanofibers.

Elastic Janus film for Wound Dressings: Unidirectional Biofluid Transport and Effectively Promoting Wound Healing

2021 ◽  
pp. 2105265
Author(s):  
Bing Xu ◽  
Ang Li ◽  
Rui Wang ◽  
Juan Zhang ◽  
Yinlong Ding ◽  
...  
Keyword(s):  
Wound Healing ◽  
Wound Dressings

scholarly journals β-Cyclodextrin/Triclosan Complex-Grafted Methacrylated Glycol Chitosan Hydorgel by Photocrosslinking via Visible Light Irradiation for a Tissue Bio-Adhesive

2021 ◽  
Vol 22 (2) ◽  
pp. 700
Author(s):  
Young Jae Moon ◽  
Sun-Jung Yoon ◽  
Jeung-Hyun Koo ◽  
Yihyun Yoon ◽  
Hye Jun Byun ◽  
...  
Keyword(s):  
Wound Healing ◽  
Bacterial Infection ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Light Irradiation ◽  
Tissue Adhesive ◽  
Proton Nuclear Magnetic Resonance ◽  
Scanning Calorimetry ◽  
Glycol Chitosan

Accelerating wound healing with minimized bacterial infection has become a topic of interest in the development of the new generation of tissue bio-adhesives. In this study, we fabricated a hydrogel system (MGC-g-CD-ic-TCS) consisting of triclosan (TCS)-complexed beta-cyclodextrin (β-CD)-conjugated methacrylated glycol chitosan (MGC) as an antibacterial tissue adhesive. Proton nuclear magnetic resonance (1H NMR) and differential scanning calorimetry (DSC) results showed the inclusion complex formation between MGC-g-CD and TCS. The increase of storage modulus (G’) of MGC-g-CD-ic-TCS after visible light irradiation for 200 s indicated its hydrogelation. The swollen hydrogel in aqueous solution resulted in two release behaviors of an initial burst and sustained release. Importantly, in vitro and in vivo results indicated that MGC-g-CD-ic-TCS inhibited bacterial infection and improved wound healing, suggesting its high potential application as an antibacterial tissue bio-adhesive.

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