Adriamycin coated silica microsphere as labels for cancer biomarker alpha-fetoprotein detection

2021 ◽  
Author(s):  
Yuzhong Zhang ◽  
Wenwen Meng ◽  
Mengrao Li
Keyword(s):  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
Silica Microspheres ◽  
Silica Microsphere

Adriamycin (ADM) coated silica microspheres as a labels for a sensitive cancer biomarker Alpha-fetoprotein (AFP) detection was reported. Silica microspheres (SiO2 MS) were employed as carrier for the immobilization of...

A mixed-function-grafted magnetic mesoporous hollow silica microsphere immobilized lipase strategy for ultrafast transesterification in a solvent-free system

RSC Advances ◽  
2015 ◽  
Vol 5 (54) ◽  
pp. 43074-43080 ◽  
Author(s):  
Mingming Zheng ◽  
Lijing Mao ◽  
Fenghong Huang ◽  
Xia Xiang ◽  
Qianchun Deng ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Immobilized Lipase ◽  
Solvent Free ◽  
Silica Microspheres ◽  
Silica Microsphere ◽  
Free System ◽  
Hollow Silica ◽  
System P ◽  
Solvent Free System

A novel magnetic mesoporous hollow silica microspheres immobilized lipase is described for ultrafast transesterification of phytosterol with fatty acids and triglycerides in a solvent-free system.

Facile and feasible conductometric immunoanalytical assay for alpha-fetoprotein using platinum-functionalized graphitic carbon nitride nanosheets

2018 ◽  
Vol 10 (40) ◽  
pp. 4886-4893 ◽  
Author(s):  
Ling Li ◽  
Wuhua Guo ◽  
Yao Lin ◽  
Dianping Tang ◽  
Jingfeng Liu
Keyword(s):  
Liver Cancer ◽  
Carbon Nitride ◽  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
Graphitic Carbon ◽  
Graphitic Carbon Nitride ◽  
Sensitive Detection ◽  
Carbon Nitride Nanosheets

A conductometric immunoanalytical method was developed for the sensitive detection of the liver cancer biomarker (alpha-fetoprotein, AFP), using platinum (Pt)-functionalized graphitic carbon nitride (g-C3N4) nanosheets..

Conductometric immunoassay of alpha-fetoprotein in sera of liver cancer patients using bienzyme-functionalized nanometer-sized silica beads

The Analyst ◽  
2019 ◽  
Vol 144 (1) ◽  
pp. 265-273 ◽  
Author(s):  
Jiaming Liang ◽  
Jing Wang ◽  
Luwei Zhang ◽  
Sijia Wang ◽  
Cuiping Yao ◽  
...  
Keyword(s):  
Liver Cancer ◽  
Cancer Patients ◽  
Biological Fluids ◽  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
Sensitive Detection ◽  
Silica Beads

A conductometric immunoassay protocol was designed for the sensitive detection of a liver cancer biomarker, alpha-fetoprotein (AFP), in biological fluids by using enzyme-conjugated nanometer-sized enzyme-doped silica beads.

SERS-active silver nanoparticle trimers for sub-attomolar detection of alpha fetoprotein

RSC Advances ◽  
2015 ◽  
Vol 5 (90) ◽  
pp. 73395-73398 ◽  
Author(s):  
Xiaoling Wu ◽  
Pan Fu ◽  
Wei Ma ◽  
Liguang Xu ◽  
Hua Kuang ◽  
...  
Keyword(s):  
Silver Nanoparticle ◽  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
First Time

SERS-active silver nanoparticle trimers were assembled in this study for the first time, through the aptamer of a cancer biomarker, alpha fetoprotein (AFP).

scholarly journals In vitro upconverting/downshifting luminescent detection of tumor markers based on Eu3+-activated core–shell–shell lanthanide nanoprobes

2016 ◽  
Vol 7 (8) ◽  
pp. 5013-5019 ◽  
Author(s):  
Yongsheng Liu ◽  
Shanyong Zhou ◽  
Zhu Zhuo ◽  
Renfu Li ◽  
Zhuo Chen ◽  
...  
Keyword(s):  
Tumor Markers ◽  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
Core Shell

We demonstrate the successful use of Eu3+-activated core–shell–shell nanoprobes for in vitro upconverting/downshifting luminescent detection of a cancer biomarker of alpha-fetoprotein.

Self-Assembled Ultra-thin Silica Layers for On-Chip Chromatography

2009 ◽  
Vol 1191 ◽  
Author(s):  
Sun Choi ◽  
Inkyu Park ◽  
Albert P Pisano
Keyword(s):  
Thin Layer ◽  
Dense Packing ◽  
Theoretical Interpretation ◽  
Micro Channel ◽  
Silica Microspheres ◽  
Silica Microsphere ◽  
Silica Suspension ◽  
Silica Alumina ◽  
Self Assembled ◽  
On Chip

AbstractWe propose a novel method for self-assembled packing of silica microsphere in micro-channel which can be potentially used for on-chip chromatography. Chromatography has been one of the most widely used techniques for the analysis and separation of the mixtures of biochemical compounds in research laboratories and industrial factories. Numerous chromatography techniques such as High-Performance Liquid Chromatography (HPLC), Thin Layer Chromatography (TLC) use absorbents (ex: silica, alumina, cellulose) as stationary phase material [1]. Effective loading of absorbents in those techniques has been a huge challenge since it requires additional implementation of high-pressure pump system (for HPLC) or limits selective coating of absorbents on supporting plate (for TLC). In order for chromatography to be efficiently integrated with micro-fluidic Lab-on-a-chip devices, novel techniques for easy and simple packing of absorbents within micro channels should be developed.Solvent-evaporation based 2-D crystallization technique [2] can enable mono-dispersed micro-particles to be self-assembled by capillary attractive forces. We apply this technique to assemble dense packing of silica microsphere and form ultra thin layers (2˜3 layers) within open microchannel. Open micro-channel has been constructed by conventional photolithography of SU8 photoresist. A small droplet (Volume: 0.1μL) of silica suspension (Diameter: 3μm, Solvent: DI Water, Concentration: 1.25wt%) has been placed in the defined inlet of micro channel. Capillary force within the open SU8 microchannel induces the flow of silica suspension in the channel. The packing of microsphere starts from the outlet side of the channel, where the thickness of solvent drastically decreases due to sudden increase of cross-sectional area of channel, and this packing propagates to the inlet side of the channel until solvent evaporates completely. As a result, a dense packing of silica microspheres are successfully assembled and a thin layer of silica microspheres are formed within open micro-channel.We will present the characterization of silica packing with regard to various process parameters and also will include theoretical interpretation of this packing technique in more detail. We will also present our future approach to integrate our technique on-chip chromatography applications.

Nanobody medicated immunoassay for ultrasensitive detection of cancer biomarker alpha-fetoprotein

Talanta ◽  
2016 ◽  
Vol 147 ◽  
pp. 523-530 ◽  
Author(s):  
Jing Chen ◽  
Qing-hua He ◽  
Yang Xu ◽  
Jin-heng Fu ◽  
Yan-ping Li ◽  
...  
Keyword(s):  
Cancer Biomarker ◽  
Alpha Fetoprotein ◽  
Ultrasensitive Detection
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