A novel fast-response and highly selective AIEgen fluorescent probe for visualizing peroxynitrite in living cells, C. elegans and inflammatory mice

The Analyst ◽  
2021 ◽  
Author(s):  
Ya-Xi Ye ◽  
Xin-Yue Chen ◽  
Ya-Wen Yu ◽  
Qing Zhang ◽  
Xiao-Wen Wei ◽  
...  
Keyword(s):  
Response Time ◽  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Fluorescence Enhancement ◽  
Fast Response ◽  
Living Cells ◽  
C Elegans

Most of ONOO− fluorescent probes have been restricted their further applications because of their aggregation-caused quenching (ACQ) effect, long response time and low fluorescence enhancement. Herein, we developed a novel...

scholarly journals Recognition of Thiols in Living Cells and Zebrafish Using an Imidazo[1,5-α]pyridine-Derivative Indicator

Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3328 ◽  
Author(s):  
Song Chen ◽  
Peng Hou ◽  
Jingwen Sun ◽  
Haijun Wang ◽  
Lei Liu
Keyword(s):  
Response Time ◽  
Fluorescent Probe ◽  
Stokes Shift ◽  
Detection Limits ◽  
Fast Response ◽  
Living Cells ◽  
Pyridine Derivative ◽  
Selective Detection ◽  
Low Cytotoxicity ◽  
Mcf 7

A new cyan fluorescent probe, MIPY-DNBS, using an imidazo[1,5-α]pyridine derivative as the fluorophore and 2,4-dinitrobenzensufonate as the recognition site for the selective detection of thiols (Cys, GSH, and Hcy), was designed and synthesized. Probe MIPY-DNBS exhibited a 172 nm Stokes shift, a fast response time (400 s), low cytotoxicity, low detection limits (12.7 nM for Cys), and excellent selectively in the detection of thiols. In addition, MIPY-DNBS was successfully applied to imaging thiols in living MCF-7 cells and zebrafish.

scholarly journals Structure modulation on fluorescent probes for biothiols and the reversible imaging of glutathione in living cells

RSC Advances ◽  
2021 ◽  
Vol 11 (34) ◽  
pp. 21116-21126
Author(s):  
Yu Li ◽  
Li Chen ◽  
Yan Zhu ◽  
Liming Chen ◽  
Xianglin Yu ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Living Cells ◽  
Structure Modulation

A reversible fluorescent probe for GSH was obtained through structure modulation, by which the intracellular GSH fluctuation was imaged.

A ratiometric fluorescence sensor for HOCl based on a FRET platform and application in living cells

RSC Advances ◽  
2016 ◽  
Vol 6 (21) ◽  
pp. 17059-17063 ◽  
Author(s):  
Yan-Ru Zhang ◽  
Zhi-Min Zhao ◽  
Le Su ◽  
Jun-Ying Miao ◽  
Bao-Xiang Zhao
Keyword(s):  
Fluorescent Probe ◽  
High Selectivity ◽  
Fast Response ◽  
Living Cells ◽  
Fluorescence Sensor ◽  
Ratiometric Fluorescence ◽  
Ratiometric Fluorescent Probe

A ratiometric fluorescent probe CRSH based on a FRET platform for detecting HOCl. CRSH showed high selectivity, excellent sensitivity and a fast response toward HOCl.

A fast response and high sensitivity thiol fluorescent probe in living cells

2016 ◽  
Vol 232 ◽  
pp. 619-624 ◽  
Author(s):  
Tao Liu ◽  
Fangjun Huo ◽  
Jianfang Li ◽  
Jianbin Chao ◽  
Yongbin Zhang ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
High Sensitivity ◽  
Fast Response ◽  
Living Cells

Fluorinated near-infrared fluorescent probes for specific detection of Hg2+ in an aqueous medium and mitochondria of living cells

2017 ◽  
Vol 41 (17) ◽  
pp. 8899-8904 ◽  
Author(s):  
Lei Long ◽  
Xu Tan ◽  
Shenglin Luo ◽  
Chunmeng Shi
Keyword(s):  
Aqueous Medium ◽  
Fluorescent Probe ◽  
Fluorescent Probes ◽  
Near Infrared ◽  
Living Cells ◽  
Specific Detection

A near-infrared fluorescent probe (IR-DFT) could be used for specifically and sensitively detecting Hg2+ in mitochondria of living cells.

scholarly journals Recent Advances on Iron(III) Selective Fluorescent Probes with Possible Applications in Bioimaging

Molecules ◽  
2019 ◽  
Vol 24 (18) ◽  
pp. 3267 ◽  
Author(s):  
Sahoo ◽  
Crisponi
Keyword(s):  
Fluorescent Probes ◽  
High Selectivity ◽  
Fluorescence Enhancement ◽  
Cost Effective ◽  
Fast Response ◽  
Vital Role ◽  
Molecular Probes ◽  
The Past ◽  
Environmental And Biological Samples ◽  
Almost All

Iron(III) is well-known to play a vital role in a variety of metabolic processes in almost all living systems, including the human body. However, the excess or deficiency of Fe3+ from the normal permissible limit can cause serious health problems. Therefore, novel analytical methods are developed for the simple, direct, and cost-effective monitoring of Fe3+ concentration in various environmental and biological samples. Because of the high selectivity and sensitivity, fast response time, and simplicity, the fluorescent-based molecular probes have been developed extensively in the past few decades to detect Fe3+. This review was narrated to summarize the Fe3+-selective fluorescent probes that show fluorescence enhancement (turn-on) and ratiometric response. The Fe3+ sensing ability, mechanisms along with the analytical novelties of recently reported 77 fluorescent probes are discussed.

A fast-response two-photon fluorescent probe for the detection of Cys over GSH/Hcy with a large turn-on signal and its application in living tissues

2017 ◽  
Vol 5 (1) ◽  
pp. 134-138 ◽  
Author(s):  
Jian-Yong Wang ◽  
Zhan-Rong Liu ◽  
Mingguang Ren ◽  
Xiuqi Kong ◽  
Weiying Lin
Keyword(s):  
Fluorescent Probe ◽  
Fast Response ◽  
Living Cells ◽  
Two Photon ◽  
Turn On ◽  
Living Tissues

We developed a novel two-photon fluorescent probe for sensing Cys specifically. The two-photon fluorescent probe exhibited favorable properties and was successfully applied for imaging Cys in living cells and tissues.

A highly selective turn-on fluorescent sensor for fluoride and its application in imaging of living cells

2014 ◽  
Vol 38 (12) ◽  
pp. 6198-6204 ◽  
Author(s):  
Jiun-Ting Yeh ◽  
Parthiban Venkatesan ◽  
Shu-Pao Wu
Keyword(s):  
Fluorescent Probe ◽  
Fluorescence Enhancement ◽  
Fluorescent Sensor ◽  
Living Cells ◽  
Green Fluorescence ◽  
Turn On ◽  
Highly Sensitive

A highly sensitive and selective fluorescent probe (FS) is based on a fluoride-specific desilylation reaction to yield a significant green fluorescence enhancement.

A fast-response fluorescent probe for hypochlorous acid detection and its application in exogenous and endogenous HOCl imaging of living cells

2017 ◽  
Vol 53 (91) ◽  
pp. 12349-12352 ◽  
Author(s):  
Yin Jiang ◽  
Guansheng Zheng ◽  
Ning Cai ◽  
Huatang Zhang ◽  
Yi Tan ◽  
...  
Keyword(s):  
Fluorescent Probe ◽  
Hypochlorous Acid ◽  
Fast Response ◽  
Living Cells

A facile fluorescent probe for exogenous and endogenous HOCl detection in living cells.

A remarkable ratiometric fluorescent chemodosimeter for very rapid detection of hydrogen sulfide in the vapour phase and living cells

2015 ◽  
Vol 39 (11) ◽  
pp. 8940-8947 ◽  
Author(s):  
Sima Paul ◽  
Shyamaprosad Goswami ◽  
Chitrangada Das Mukhopadhyay
Keyword(s):  
Hydrogen Sulfide ◽  
Fluorescent Probe ◽  
Fluorescence Imaging ◽  
Rapid Detection ◽  
Stokes Shift ◽  
Vapour Phase ◽  
Fast Response ◽  
Living Cells ◽  
Fluorescent Chemodosimeter ◽  
Ratiometric Fluorescent Probe

A ratiometric fluorescent probe having a fast response and a large Stokes shift detects SH− both in solid and vapour phases and this probe is used for fluorescence imaging of SH− in living cells.

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