Novel tri-[2]rotaxane-based stimuli-responsive fluorescent nanoparticles and their guest controlled reversible morphological transformation properties

2021 ◽  
Vol 9 (11) ◽  
pp. 3863-3870
Author(s):  
Qi Lin ◽  
Zhong-Hui Wang ◽  
Ting-Ting Huang ◽  
Tai-Bao Wei ◽  
Hong Yao ◽  
...  
Keyword(s):  
Fluorescent Nanoparticles ◽  
Stimuli Responsive ◽  
Suberic Acid ◽  
Morphological Transformation ◽  
Fluorescence Response ◽  
Fluorescent Nanomaterials

Novel tri-[2]rotaxane-based fluorescent nanomaterials show selective fluorescence response towards suberic acid and could reversibly switch from nanoparticles to nano-film.

Fluorescent Nanotechnology: An Evolution in Optical Sensors

2020 ◽  
Vol 17 ◽  
Author(s):  
Dilawar Hassan ◽  
Hadi Bakhsh ◽  
Asif M. Khurram ◽  
Shakeel A. Bhutto ◽  
Nida S. Jalbani ◽  
...  
Keyword(s):  
Optical Properties ◽  
Optical Sensors ◽  
Light Emission ◽  
Environmental Contaminants ◽  
Fluorescent Nanoparticles ◽  
Sensing Applications ◽  
Properties Of Materials ◽  
Optical Properties Of Materials ◽  
Fluorescent Nanomaterials

Background: The optical properties of nanomaterials have evolved enormously with the introduction of nanotechnology. The property of materials to absorb and/or emit specific wavelength has turned them into one of the most favourite candidates to be effectively utilized in different sensing applications e.g organic light emission diodes (OLEDs) sensors, gas sensors, biosensors and fluorescent sensors. These materials have been reported as a sensor in the field of tissue and cell imaging, cancer detection and detection of environmental contaminants etc. Fluorescent nanomaterials are heling in rapid and timely detection of various contaminants that greatly impact the quality of life and food, that is exposed to these contaminants. Later, all the contaminants have been investigated to be most perilous entities that momentously affect the life span of the animals and humans who use those foods which have been contaminated. Objective: In this review, we will discuss about various methods and approaches to synthesize the fluorescent nanoparticles and quantum dots (QDs) and their applications in various fields. The application will include the detection of various environmental contaminants and bio-medical applications. We will discuss the possible mode of action of the nanoparticles when used as sensor for the environmental contaminants as well as the surface modification of some fluorescent nanomaterials with anti-body and enzyme for specific detection in animal kingdom. We will also describe some RAMAN based sensors as well as some optical sensing-based nanosensors. Conclusion: Nanotechnology has enabled to play with the size, shape and morphology of materials in the nanoscale. The physical, chemical and optical properties of materials change dramatically when they are reduced to nanoscale. The optical properties can become choosy in terms of emission or absorption of wavelength in the size range and can result in production of very sensitive optical sensor. The results show that the use of fluorescent nanomaterials for the sensing purposes are helping a great deal in the sensing field.

Recapitulation of Cancer Nanotherapeutics

2021 ◽  
Vol 11 ◽  
Author(s):  
Dilip Morani ◽  
Pravin Patil ◽  
Ashish Jain
Keyword(s):  
Anticancer Agents ◽  
Active Agent ◽  
Cancer Site ◽  
Fluorescent Nanoparticles ◽  
Design Development ◽  
Cancer Disease ◽  
Potential Applications ◽  
Current Scenario ◽  
Fluorescent Nanomaterials ◽  
Nano Size

: Recently, nanotherapeutics has revolutionized the major impact on healthcare strategies and health facilities. Nanotherapeutics includes design, development and application of therapeutic agents having nano-size (1-100 nm). Due to implications in gene therapy and drug delivery, nanotherapeutics has received much interest in the current scenario. The major area where research is going on and giving maximum benefits from nano-based delivery system includes cancer diagnosis and targeting. The nanotherapeutics are designed in such a way that they will overcome the major drawbacks of conventional therapy and have multi-functionalities so that it can be targeted to cancer site. Nanotherapeutics have increased the permeability and retention of anticancer agents thereby targeting them to the tumor site. Nanotherapeutics has increased the effectiveness of anticancer agents with less or no toxicity. Likewise, diagnostic imaging is also possible with fluorescent nanoparticles based nanotherapeutics and has major potential applications in recent upcoming years with newer fluorescent nanomaterials for specific cancer targeting. Background- NTs provided the possibility of delivering drugs to specific cells using nanoparticles. The overall drug consumption and side-effects may be lowered significantly by depositing the active agent in the morbid region only and in no higher dose than needed. Aim- Attempt have been made to define the nanotherapeutics and to compile the latest developments in the field. Because the topic is of high importance to the general human wellbeing and covers recapitulation of cancer nanotherapeutics and summarizes and restates the main points of nanotherapeutics in the treatment of cancer disease.

scholarly journals Fluorescent Nanoparticles Synthesized from DNA, RNA, and Nucleotides

Nanomaterials ◽  
2021 ◽  
Vol 11 (9) ◽  
pp. 2265 ◽  
Author(s):  
Maofei Wang ◽  
Masaki Tsukamoto ◽  
Vladimir G. Sergeyev ◽  
Anatoly Zinchenko
Keyword(s):  
Nucleic Acids ◽  
Fluorescent Nanoparticles ◽  
Fluorescent Product ◽  
Fluorescent Properties ◽  
Dna And Rna ◽  
Biomass Resources ◽  
Fluorescent Nanomaterials ◽  
The Relationship ◽  
Acid Precursor ◽  
Unique Chemical

Ubiquitous on Earth, DNA and other nucleic acids are being increasingly considered as promising biomass resources. Due to their unique chemical structure, which is different from that of more common carbohydrate biomass polymers, materials based on nucleic acids may exhibit new, attractive characteristics. In this study, fluorescent nanoparticles (biodots) were prepared by a hydrothermal (HT) method from various nucleic acids (DNA, RNA, nucleotides, and nucleosides) to establish the relationship between the structure of precursors and fluorescent properties of biodots and to optimize conditions for preparation of the most fluorescent product. HT treatment of nucleic acids results in decomposition of sugar moieties and depurination/depyrimidation of nucleobases, while their consequent condensation and polymerization gives fluorescent nanoparticles. Fluorescent properties of DNA and RNA biodots are drastically different from biodots synthesized from individual nucleotides. In particular, biodots synthesized from purine-containing nucleotides or nucleosides show up to 50-fold higher fluorescence compared to analogous pyrimidine-derived biodots. The polymeric nature of a precursor disfavors formation of a bright fluorescent product. The reported effect of the structure of the nucleic acid precursor on the fluorescence properties of biodots should help designing and synthesizing brighter fluorescent nanomaterials with broader specification for bioimaging, sensing, and other applications.

scholarly journals Advances and Challenges of Fluorescent Nanomaterials for Synthesis and Biomedical Applications

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Deli Xiao ◽  
Haixiang Qi ◽  
Yan Teng ◽  
Dramou Pierre ◽  
Perpetua Takunda Kutoka ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Rapid Development ◽  
Critical Role ◽  
Clinical Applications ◽  
Noble Metal Nanoparticles ◽  
Nanometer Scale ◽  
Fluorescent Nanoparticles ◽  
Future Directions ◽  
The Past ◽  
Fluorescent Nanomaterials

AbstractWith the rapid development of nanotechnology, new types of fluorescent nanomaterials (FNMs) have been springing up in the past two decades. The nanometer scale endows FNMs with unique optical properties which play a critical role in their applications in bioimaging and fluorescence-dependent detections. However, since low selectivity as well as low photoluminescence efficiency of fluorescent nanomaterials hinders their applications in imaging and detection to some extent, scientists are still in search of synthesizing new FNMs with better properties. In this review, a variety of fluorescent nanoparticles are summarized including semiconductor quantum dots, carbon dots, carbon nanoparticles, carbon nanotubes, graphene-based nanomaterials, noble metal nanoparticles, silica nanoparticles, phosphors and organic frameworks. We highlight the recent advances of the latest developments in the synthesis of FNMs and their applications in the biomedical field in recent years. Furthermore, the main theories, methods, and limitations of the synthesis and applications of FNMs have been reviewed and discussed. In addition, challenges in synthesis and biomedical applications are systematically summarized as well. The future directions and perspectives of FNMs in clinical applications are also presented.

Organic nanoparticles composed of Fréchet-type dendrons: synthesis, characterization, self-assembly and reversible guest encapsulation

2014 ◽  
Vol 2 (34) ◽  
pp. 5576-5584 ◽  
Author(s):  
Sreedevi Krishnakumar ◽  
Karical R. Gopidas
Keyword(s):  
Gold Nanoparticle ◽  
Self Assembly ◽  
Stimuli Responsive ◽  
Morphological Transformation ◽  
One Pot ◽  
Organic Nanoparticles ◽  
On Demand ◽  
Gold Core ◽  
Self Assembled

Novel Fréchet-type dendron based organic nanodots exhibiting stimuli responsive reversible morphological transformation have been synthesized by a one-pot reaction which involves etching off gold core of a gold nanoparticle cored dendrimer. Self-assembled FDNs can be utilized for encapsulation and on-demand release of guests.

scholarly journals Redox-responsive, reversibly fluorescent nanoparticles from sustainable cellulose derivatives

2014 ◽  
Vol 2 (33) ◽  
pp. 13675-13681 ◽  
Author(s):  
Wei Li ◽  
Wei Wang ◽  
Yongbiao Yang ◽  
Kai Zhang
Keyword(s):  
Fluorescent Nanoparticles ◽  
Cellulose Derivatives ◽  
Stimuli Responsive ◽  
Redox Responsive ◽  
Fluorescent Compounds

Multi-stimuli responsive and reversibly fluorescent compounds from sustainable cellulose were synthesized after the introduction of thiol and rhodamine spiroamide groups.

scholarly journals Core–shell polymeric nanoparticles comprising BODIPY and fluorescein as ultra-bright ratiometric fluorescent pH sensors

2019 ◽  
Vol 18 (5) ◽  
pp. 1156-1165 ◽  
Author(s):  
Chloé Grazon ◽  
Yang Si ◽  
Jean-Pierre Placial ◽  
Jutta Rieger ◽  
Rachel Méallet-Renault ◽  
...  
Keyword(s):  
Polymeric Nanoparticles ◽  
Ph Sensitive ◽  
Core Shell ◽  
Fluorescent Nanoparticles ◽  
Ph Sensors ◽  
Fluorescence Response

Ultra-bright pH-sensitive fluorescent nanoparticles, including BODIPY in their core and fluorescein in their shell, are synthesized. They contain more than 2500 fluorophores and exhibit a linear fluorescence response between pH 5.5 and 7.5.

Ultra-bright and stimuli-responsive fluorescent nanoparticles for bioimaging

2015 ◽  
Vol 8 (1) ◽  
pp. 139-150 ◽  
Author(s):  
Giulia Battistelli ◽  
Andrea Cantelli ◽  
Gloria Guidetti ◽  
Jeannette Manzi ◽  
Marco Montalti
Keyword(s):  
Fluorescent Nanoparticles ◽  
Stimuli Responsive

Amino-functional polyethers: versatile, stimuli-responsive polymers

2020 ◽  
Vol 11 (24) ◽  
pp. 3940-3950 ◽  
Author(s):  
Patrick Verkoyen ◽  
Holger Frey
Keyword(s):  
Ring Opening ◽  
Review Article ◽  
Stimuli Responsive ◽  
New Class ◽  
Stimuli Responsive Polymers ◽  
Responsive Polymers

Amino-functional polyethers have emerged as a new class of “smart”, i.e. pH- and thermoresponsive materials. This review article summarizes the synthesis and applications of these materials, obtained from ring-opening of suitable epoxide monomers.

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