A class of water-soluble Fe(iii) coordination complexes as T1-weighted MRI contrast agents

2021 ◽  
Vol 9 (7) ◽  
pp. 1787-1791
Author(s):  
Run Wang ◽  
Lu An ◽  
Jing He ◽  
Mengmeng Li ◽  
Jingjing Jiao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Contrast Agents ◽  
Coordination Complexes ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Contrast ◽  
Weighted Magnetic Resonance Imaging

Water-soluble Fe(iii) coordination complexes were fabricated as T1-weighted magnetic resonance imaging contrast agents in vivo.

scholarly journals Uniform Fe3O4/Gd2O3-DHCA nanocubes for dual-mode magnetic resonance imaging

2020 ◽  
Vol 11 ◽  
pp. 1000-1009
Author(s):  
Miao Qin ◽  
Yueyou Peng ◽  
Mengjie Xu ◽  
Hui Yan ◽  
Yizhu Cheng ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Clinical Diagnostics ◽  
Resonance Imaging ◽  
Dual Mode ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Mri

The multimodal magnetic resonance imaging (MRI) technique has been extensively studied over the past few years since it offers complementary information that can increase diagnostic accuracy. Simple methods to synthesize contrast agents are necessary for the development of multimodal MRI. Herein, uniformly distributed Fe3O4/Gd2O3 nanocubes for T 1–T 2 dual-mode MRI contrast agents were successfully designed and synthesized. In order to increase hydrophilicity and biocompatibility, the nanocubes were coated with nontoxic 3,4-dihydroxyhydrocinnamic acid (DHCA). The results show that iron (Fe) and gadolinium (Gd) were homogeneously distributed throughout the Fe3O4/Gd2O3-DHCA (FGDA) nanocubes. Relaxation time analysis was performed on the images obtained from the 3.0 T scanner. The results demonstrated that r 1 and r 2 maximum values were 67.57 ± 6.2 and 24.2 ± 1.46 mM−1·s−1, respectively. In vivo T 1- and T 2-weighted images showed that FGDA nanocubes act as a dual-mode contrast agent enhancing MRI quality. Overall, these experimental results suggest that the FGDA nanocubes are interesting tools that can be used to increase MRI quality, enabling accurate clinical diagnostics.

Investigation of cyano-bridged coordination nanoparticles Gd3+/[Fe(CN)6]3−/d-mannitol as T1-weighted MRI contrast agents

Nanoscale ◽  
2015 ◽  
Vol 7 (28) ◽  
pp. 11899-11903 ◽  
Author(s):  
M. Perrier ◽  
A. Gallud ◽  
A. Ayadi ◽  
S. Kennouche ◽  
C. Porredon ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Mri Contrast

Ultra small Gd3+/[Fe(CN)6]3− nanoparticles are investigated in vivo as contrast agents for Magnetic Resonance Imaging.

The Application Of Molecular Sieves As Magnetic Resonance Imaging Contrast Agents

1991 ◽  
Vol 233 ◽  
Author(s):  
Kenneth J. Balkus ◽  
Iwona Bresinska ◽  
Stanislaw Kowalak ◽  
Stuart W. Young
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Molecular Sieves ◽  
Mri Contrast Agents ◽  
Paramagnetic Species ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Magnetic Resonance Imaging Contrast ◽  
Magnetic Resonance Imaging Mri

ABSTRACTThe application of zeolite molecular sieves as Magnetic Resonance Imaging (MRI) contrast agents is presented. Recent progress is described for X, Y and A type zeolites modified with paramagnetic species.

Facile synthesis of manganese silicate nanoparticles for pH/GSH-responsive T1-weighted magnetic resonance imaging

2016 ◽  
Vol 4 (24) ◽  
pp. 4313-4321 ◽  
Author(s):  
X. W. Li ◽  
W. R. Zhao ◽  
Y. J. Liu ◽  
X. H. Liu ◽  
P. Shi ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Cancer Diagnosis ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Facile Synthesis ◽  
Mri Contrast ◽  
Manganese Silicate ◽  
Weighted Magnetic Resonance Imaging

Manganese silicate nanoparticles were facilely synthesized and showed high potential as T1-MRI contrast agents for cancer diagnosis.

Facile one-pot synthesis of different surfactant-functionalized water-soluble Fe3O4 nanoparticles as magnetic resonance imaging contrast agents for melanoma tumors

RSC Advances ◽  
2015 ◽  
Vol 5 (62) ◽  
pp. 50557-50564 ◽  
Author(s):  
Longyun Wu ◽  
ChunYan Yang ◽  
Zhongwen Lv ◽  
FengWen Cui ◽  
Lijun Zhao ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Mr Imaging ◽  
Contrast Agents ◽  
Sodium Citrate ◽  
Water Soluble ◽  
Resonance Imaging ◽  
One Pot ◽  
Magnetic Resonance Imaging Contrast

A facile and efficient one-pot solvothermal strategy is described to synthesize Fe3O4 nanoparticles (NPs) modified with sodium citrate, polyvinylpyrrolidone and l-asparagine for in vivo magnetic resonance (MR) imaging of melanoma cells.

HP-DO3A-based amphiphilic MRI contrast agents and relaxation enhancement through their assembly with polyelectrolytes

2016 ◽  
Vol 4 (45) ◽  
pp. 7241-7248 ◽  
Author(s):  
Qin Zhu ◽  
Heng Yang ◽  
Yuanyuan Li ◽  
Yu Tian ◽  
Wei Wang ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Self Assembly ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Good Biocompatibility ◽  
Magnetic Resonance Imaging Mri

HP-DO3A-based amphiphilic magnetic resonance imaging (MRI) contrast agents show electrostatic self-assembly ability with polyelectrolytes, good biocompatibility, and significant contrast enhancement in in vivo imaging.

Water-soluble d-glucuronic acid coated ultrasmall mixed Ln/Mn (Ln = Gd and Dy) oxide nanoparticles and their application to magnetic resonance imaging

2014 ◽  
Vol 2 (9) ◽  
pp. 1287-1295 ◽  
Author(s):  
Badrul Alam Bony ◽  
Jong Su Baeck ◽  
Yongmin Chang ◽  
Ji Eun Bae ◽  
Kwon Seok Chae ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Glucuronic Acid ◽  
Mri Contrast Agents ◽  
Water Soluble ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Mn Oxide

Mixed (A) Gd/Mn and (B) Dy/Mn oxide nanoparticles are confirmed to be potential T1 and/or T2 MRI contrast agents, respectively.

Gadolinium(iii) based nanoparticles for T1-weighted magnetic resonance imaging probes

RSC Advances ◽  
2016 ◽  
Vol 6 (65) ◽  
pp. 60945-60966 ◽  
Author(s):  
Chang-Tong Yang ◽  
Parasuraman Padmanabhan ◽  
Balázs Z. Gulyás
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Recent Progress ◽  
Mri Contrast Agents ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Imaging Probes ◽  
Weighted Magnetic Resonance Imaging

This review summarized the recent progress on Gd(iii)-based nanoparticles asT1-weighted MRI contrast agents and multimodal contrast agents.

Biocompatible dextran-coated gadolinium-doped cerium oxide nanoparticles as MRI contrast agents with high T1 relaxivity and selective cytotoxicity to cancer cells

2021 ◽  
Author(s):  
Anton Popov ◽  
Maxim Artemovich Abakumov ◽  
Irina Savintseva ◽  
Artem Ermakov ◽  
Nelly Popova ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Contrast Agents ◽  
Mri Contrast Agents ◽  
Cerium Oxide Nanoparticles ◽  
Oxide Nanoparticles ◽  
Resonance Imaging ◽  
Mri Contrast ◽  
Selective Cytotoxicity ◽  
Magnetic Resonance Imaging Mri

Gd-based complexes are widely used as magnetic resonance imaging (MRI) contrast agents. The safety of previously approved contrast agents is questionable and is being re-assessed. The main causes of concern...

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