Biodegradable copper–metformin nanoscale coordination polymers for enhanced chemo/chemodynamic synergistic therapy by reducing oxygen consumption to promote H2O2 accumulation

2021 ◽  
Author(s):  
Xiangyu Meng ◽  
Xuezhong Zhang ◽  
Yunfeng Lei ◽  
Dongwei Cao ◽  
Zhifei Wang
Keyword(s):  
Oxygen Consumption ◽  
Coordination Polymers ◽  
H2o2 Accumulation ◽  
Nanoscale Coordination Polymers

A new therapeutic nanoplatform based on Dox@Cu–Met NPs was constructed, which could reduce the consumption of O2 and elevate H2O2 content for effective chemo/chemodynamic synergistic therapy.

Synthesis of Nanoscale Coordination Polymers in Femtoliter Reactors on Surfaces

ACS Nano ◽  
2016 ◽  
Vol 10 (3) ◽  
pp. 3206-3213 ◽  
Author(s):  
Mireia Guardingo ◽  
Pablo González-Monje ◽  
Fernando Novio ◽  
Elena Bellido ◽  
Félix Busqué ◽  
...  
Keyword(s):  
Coordination Polymers ◽  
Nanoscale Coordination Polymers

scholarly journals Highly Effective Radioisotope Cancer Therapy with a Non-Therapeutic Isotope Delivered and Sensitized by Nanoscale Coordination Polymers

ACS Nano ◽  
2018 ◽  
Vol 12 (8) ◽  
pp. 7519-7528 ◽  
Author(s):  
Yu Chao ◽  
Chao Liang ◽  
Yu Yang ◽  
Guanglin Wang ◽  
Debabrata Maiti ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
Coordination Polymers ◽  
Highly Effective ◽  
Nanoscale Coordination Polymers

Methotrexate–Mn2+ based nanoscale coordination polymers as a theranostic nanoplatform for MRI guided chemotherapy

2020 ◽  
Vol 8 (2) ◽  
pp. 712-719 ◽  
Author(s):  
Yan Wu ◽  
Li Xu ◽  
Jiwen Qian ◽  
Leilei Shi ◽  
Yue Su ◽  
...  
Keyword(s):  
Coordination Polymers ◽  
Antitumor Effects ◽  
Uniform Size ◽  
Mri Guided ◽  
Nanoscale Coordination Polymers

Methotrexate–Mn2+ based NCPs with uniform size and easy fabrication exhibited good MRI and excellent antitumor effects as a novel theranostic nanoplatform.

Theranostic nanoscale coordination polymers for magnetic resonance imaging and bisphosphonate delivery

2014 ◽  
Vol 2 (46) ◽  
pp. 8249-8255 ◽  
Author(s):  
Demin Liu ◽  
Chunbai He ◽  
Christopher Poon ◽  
Wenbin Lin
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Cancer Therapy ◽  
Coordination Polymers ◽  
Resonance Imaging ◽  
Weighted Magnetic Resonance Imaging ◽  
Nanoscale Coordination Polymers

Mn-zoledronate NCP carries 63 wt% of zoledronate for cancer therapy and 13 wt% of Mn2+ for T1-weighted magnetic resonance imaging.

Redox-Sensitive Nanoscale Coordination Polymers for Drug Delivery and Cancer Theranostics

2017 ◽  
Vol 9 (28) ◽  
pp. 23555-23563 ◽  
Author(s):  
Jiayue Zhao ◽  
Yu Yang ◽  
Xiao Han ◽  
Chao Liang ◽  
Jingjing Liu ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Coordination Polymers ◽  
Cancer Theranostics ◽  
Nanoscale Coordination Polymers
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