In situ oxygenating and 808 nm light-sensitized nanocomposite for multimodal imaging and mitochondria-assisted cancer therapy

2021 ◽  
Vol 9 (1) ◽  
pp. 131-146
Author(s):  
Arif Gulzar ◽  
Fei He ◽  
Aanisa Gulzar ◽  
Ye Kuang ◽  
Fangmei Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Elevated Level ◽  
Hypoxic Environment

The efficiency of photodynamic therapy (PDT) is severely constrained due to the innate hypoxic environment, besides the elevated level of glutathione (GSH).

pH/redox dual-stimuli-responsive cross-linked polyphosphazene nanoparticles for multimodal imaging-guided chemo-photodynamic therapy

Nanoscale ◽  
2019 ◽  
Vol 11 (19) ◽  
pp. 9457-9467 ◽  
Author(s):  
Xunan Jing ◽  
Zhe Zhi ◽  
Liming Jin ◽  
Fei Wang ◽  
Youshen Wu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Multimodal Imaging ◽  
Great Promise ◽  
Stimuli Responsive

Multifunctional nanodrugs with the integration of precise diagnostic and effective therapeutic functions have shown great promise in improving the efficacy of cancer therapy.

New strategy for precise cancer therapy: tumor-specific delivery of mitochondria-targeting photodynamic therapy agents and in situ O2-generation in hypoxic tumors

2020 ◽  
Vol 8 (14) ◽  
pp. 3994-4002
Author(s):  
Huachao Chen ◽  
Chengkun He ◽  
Tianyi Chen ◽  
Xuling Xue
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Cancer Treatment ◽  
New Strategy ◽  
Mitochondria Targeting

This work reports new ROS-responsive and O2-producing nanoparticles to achieve selective and mitochondria-targeted PDT for cancer treatment against hypoxic tumors.

scholarly journals Correction: A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy

2021 ◽  
Vol 9 (10) ◽  
pp. 2549-2549
Author(s):  
Mengxue Liu ◽  
Jiulong Zhang ◽  
Xin Li ◽  
Chao Cai ◽  
Xueyan Cao ◽  
...  
Keyword(s):  
Iron Oxide ◽  
Cancer Therapy ◽  
Multimodal Imaging

Correction for ‘A polydopamine-coated LAPONITE®-stabilized iron oxide nanoplatform for targeted multimodal imaging-guided photothermal cancer therapy’ by Mengxue Liu et al., J. Mater. Chem. B, 2019, 7, 3856–3864, DOI: 10.1039/c9tb00398c.

Biodegradable Nano-photosensitizer with Photoactivatable Singlet Oxygen Generation for Synergistic Phototherapy

2021 ◽  
Author(s):  
Jiaxin Shen ◽  
Dandan Chen ◽  
Ye Liu ◽  
Guoyang Gao ◽  
Zhihe Liu ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapy ◽  
Singlet Oxygen ◽  
Near Infrared ◽  
Promising Method ◽  
Normal Cells ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Nir Light

Photodynamic therapy (PDT) is a promising method for cancer therapy and also may initiate unexpected damages to normal cells and tissues. Herein, we developed a near-infrared (NIR) light-activatable nanophotosensitizer, which...

scholarly journals In situ second-harmonic generation mediated photodynamic therapy by micelles co-encapsulating coordination nanoparticle and photosensitizer

RSC Advances ◽  
2017 ◽  
Vol 7 (82) ◽  
pp. 52125-52132 ◽  
Author(s):  
Xuyang Zhou ◽  
Yang Chen ◽  
Jian Su ◽  
Xiaohe Tian ◽  
Yonghuang Luo ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Second Harmonic Generation ◽  
Harmonic Generation ◽  
Nonlinear Optical ◽  
Second Harmonic ◽  
Property A

NIR-PDT strategy was introduced by employing a nonlinear optical conveyor bearing strong second-harmonic generation (SHG) property. A biocompatible micellic system co-delivered the conveyor and photosensitizer for in situ NIR-PDT.

In Situ Growth of CuS/SiO2-Based Multifunctional Nanotherapeutic Agents for Combined Photodynamic/Photothermal Cancer Therapy

2018 ◽  
Vol 10 (37) ◽  
pp. 31008-31018 ◽  
Author(s):  
Xiangmei Liu ◽  
Tianshe Yang ◽  
Yifan Han ◽  
Liang Zou ◽  
Huiran Yang ◽  
...  
Keyword(s):  
Cancer Therapy ◽  
In Situ Growth
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