Inhibition and disaggregation of amyloid β protein fibrils through conjugated polymer–core thermoresponsive micelles

Hao Geng; Hongbo Yuan; Liang Qiu; Dong Gao; Yongqiang Cheng; Chengfen Xing

doi:10.1039/d0tb01863e

Inhibition and disaggregation of amyloid β protein fibrils through conjugated polymer–core thermoresponsive micelles

Journal of Materials Chemistry B ◽

10.1039/d0tb01863e ◽

2020 ◽

Vol 8 (44) ◽

pp. 10126-10135

Author(s):

Hao Geng ◽

Hongbo Yuan ◽

Liang Qiu ◽

Dong Gao ◽

Yongqiang Cheng ◽

...

Keyword(s):

Reactive Oxygen Species ◽

White Light ◽

Conjugated Polymer ◽

Amyloid Β ◽

Reactive Oxygen ◽

Light Irradiation ◽

Amyloid Β Protein ◽

Oxygen Species ◽

Β Protein ◽

Protein Fibrils

The micelles (CPMs) have a thermoresponsive surface and reactive oxygen species (ROS) generating core. At 37 °C, CPMs captured Aβ aggregates to inhibit and disaggregate aggregates under white-light irradiation, reducing Aβ-induced cytotoxicity.

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Improved detection of reactive oxygen species by DCFH-DA: New insight into self-amplification of fluorescence signal by light irradiation

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2021.129878 ◽

2021 ◽

Vol 339 ◽

pp. 129878

Author(s):

Daliang Yu ◽

Yingying Zha ◽

Zheng Zhong ◽

Yiming Ruan ◽

Ziwei Li ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Reactive Oxygen ◽

Light Irradiation ◽

Fluorescence Signal ◽

Oxygen Species ◽

Insight Into

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A Water‐Soluble Peptoid Chelator that Can Remove Cu 2+ from Amyloid‐β Peptides and Stop the Formation of Reactive Oxygen Species Associated with Alzheimer's Disease

Angewandte Chemie ◽

10.1002/ange.202109758 ◽

2021 ◽

Author(s):

Anastasia E. Behar ◽

Laurent Sabater ◽

Maria Baskin ◽

Christelle Hureau ◽

Galia Maayan

Keyword(s):

Alzheimer’S Disease ◽

Reactive Oxygen Species ◽

Alzheimer's Disease ◽

Amyloid Β ◽

Reactive Oxygen ◽

Water Soluble ◽

Oxygen Species

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Differential efficacy of lipophilic and cytosolic antioxidants on generation of reactive oxygen species by amyloid-β

Journal of Alzheimer s Disease ◽

10.3233/jad-2001-3602 ◽

2001 ◽

Vol 3 (6) ◽

pp. 525-529 ◽

Cited By ~ 17

Author(s):

Sirikarnt Dhitavat ◽

E.R. Rivera ◽

Eugene Rogers ◽

Thomas B. Shea

Keyword(s):

Reactive Oxygen Species ◽

Amyloid Β ◽

Reactive Oxygen ◽

Oxygen Species

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Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro

Nanoscale Research Letters ◽

10.1186/s11671-018-2720-1 ◽

2018 ◽

Vol 13 (1) ◽

Cited By ~ 8

Author(s):

Licong Yang ◽

Na Wang ◽

Guodong Zheng

Keyword(s):

Reactive Oxygen Species ◽

Chlorogenic Acid ◽

Amyloid Β ◽

Reactive Oxygen ◽

Selenium Nanoparticles ◽

Oxygen Species ◽

Reactive Oxygen Species Formation ◽

Species Formation

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Fabrication of magnetic BaFe12O19/Ag3PO4 composites with an in situ photo-Fenton-like reaction for enhancing reactive oxygen species under visible light irradiation

Catalysis Science & Technology ◽

10.1039/c8cy02449a ◽

2019 ◽

Vol 9 (10) ◽

pp. 2563-2570 ◽

Cited By ~ 8

Author(s):

Yuanguo Xu ◽

Feiyue Ge ◽

Meng Xie ◽

Shuquan Huang ◽

Junchao Qian ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Visible Light ◽

Visible Light Irradiation ◽

Reactive Oxygen ◽

Light Irradiation ◽

Oh Radicals ◽

Oxygen Species

An in situ photo-Fenton-like and magnetic recycle system, BaFe12O19/Ag3PO4 has been constructed. BaFe12O19 can catalyze the conversion of H2O2 to generate ROSs (˙O2− and ˙OH radicals) on the surface of Ag3PO4.

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Metal-Binding to Amyloid-β Peptide: Coordination, Aggregation, and Reactive Oxygen Species Production

Biometals in Neurodegenerative Diseases ◽

10.1016/b978-0-12-804562-6.00014-2 ◽

2017 ◽

pp. 265-281 ◽

Cited By ~ 5

Author(s):

Melisa del Barrio ◽

Valentina Borghesani ◽

Christelle Hureau ◽

Peter Faller

Keyword(s):

Reactive Oxygen Species ◽

Metal Binding ◽

Reactive Oxygen Species Production ◽

Amyloid Β ◽

Reactive Oxygen ◽

Amyloid Β Peptide ◽

Oxygen Species ◽

Species Production

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P1-186: SUBTLE GENOMIC DNA DAMAGE LEADS TO INCREASE IN AMYLOID-β(1-42) LEVELS WITHOUT PRODUCING REACTIVE OXYGEN SPECIES

Alzheimer s & Dementia ◽

10.1016/j.jalz.2018.06.190 ◽

2006 ◽

Vol 14 (7S_Part_6) ◽

pp. P349-P350

Author(s):

Hrishita Das ◽

Ramesh Kumar ◽

Subhas Chandra Biswas

Keyword(s):

Reactive Oxygen Species ◽

Dna Damage ◽

Genomic Dna ◽

Amyloid Β ◽

Reactive Oxygen ◽

Oxygen Species

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Reactive Oxygen Species-Related Inside-to-Outside Oxidation of Soot Particles Triggered by Visible-Light Irradiation: Physicochemical Property Changes and Oxidative Potential Enhancement

Environmental Science & Technology ◽

10.1021/acs.est.0c01150 ◽

2020 ◽

Vol 54 (14) ◽

pp. 8558-8567 ◽

Cited By ~ 1

Author(s):

Jiali Zhu ◽

Jing Shang ◽

Yueyue Chen ◽

Yu Kuang ◽

Tong Zhu

Keyword(s):

Reactive Oxygen Species ◽

Physicochemical Property ◽

Visible Light ◽

Visible Light Irradiation ◽

Reactive Oxygen ◽

Light Irradiation ◽

Oxygen Species ◽

Oxidative Potential ◽

Soot Particles ◽

Property Changes

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Blue LED light irradiation enhances L-ascorbic acid content while reducing reactive oxygen species accumulation in Chinese cabbage seedlings

Scientia Horticulturae ◽

10.1016/j.scienta.2019.108924 ◽

2020 ◽

Vol 261 ◽

pp. 108924 ◽

Cited By ~ 2

Author(s):

Chang Ho Kang ◽

Eun Kyung Yoon ◽

Muthusamy Muthusamy ◽

Jin A. Kim ◽

Mi-Jeong Jeong ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Ascorbic Acid ◽

Chinese Cabbage ◽

Acid Content ◽

Reactive Oxygen ◽

Ascorbic Acid Content ◽

Light Irradiation ◽

Oxygen Species ◽

Blue Led ◽

Led Light

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Exciton dissociation in an NIR-active triohybrid nanocrystal leading to efficient generation of reactive oxygen species

Physical Chemistry Chemical Physics ◽

10.1039/c9cp01923e ◽

2019 ◽

Vol 21 (20) ◽

pp. 10667-10676 ◽

Cited By ~ 1

Author(s):

Jayita Patwari ◽

Harmit Joshi ◽

Harahari Mandal ◽

Lopamudra Roy ◽

Chinmoy Bhattacharya ◽

...

Keyword(s):

Reactive Oxygen Species ◽

Reactive Oxygen ◽

Light Irradiation ◽

Oxygen Species ◽

Exciton Dissociation ◽

Efficient Generation ◽

Key Factor ◽

Ir Light

Exciton dissociation: the key factor in generating ROS under IR light irradiation.

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