Exciton dissociation in an NIR-active triohybrid nanocrystal leading to efficient generation of reactive oxygen species

2019 ◽  
Vol 21 (20) ◽  
pp. 10667-10676 ◽  
Author(s):  
Jayita Patwari ◽  
Harmit Joshi ◽  
Harahari Mandal ◽  
Lopamudra Roy ◽  
Chinmoy Bhattacharya ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Light Irradiation ◽  
Oxygen Species ◽  
Exciton Dissociation ◽  
Efficient Generation ◽  
Key Factor ◽  
Ir Light

Exciton dissociation: the key factor in generating ROS under IR light irradiation.

scholarly journals Experimental Hepatic Carcinogenesis: Oxidative Stress and Natural Antioxidants

2017 ◽  
Vol 5 (5) ◽  
pp. 686-691 ◽  
Author(s):  
Velid Unsal ◽  
Ergül Belge-Kurutaş
Keyword(s):  
Oxidative Stress ◽  
Reactive Oxygen Species ◽  
Reactive Oxygen ◽  
Natural Antioxidants ◽  
Toxic Substances ◽  
Oxygen Species ◽  
Leading Role ◽  
Hepatic Carcinogenesis ◽  
Key Factor ◽  
Tumour Promoters

Hepatocellular carcinoma is one of the most common cancers in the world, and it is influenced by agents such as DEN, 2-AAF, phenobarbital, alcohol, aflatoxin B1 metabolite or hepatitis viruses (B and C). Oxidative stress is becoming recognized as a key factor in the progression of hepatocarcinogenesis. Reactive oxygen species can play a leading role in initiation and promotion of hepatic carcinogenesis. The metabolites of DEN Diethylnitrosamine (DEN) mediate the binding of tumour promoters by covalently binding to the DNA with one or two oxidation-providing electrons. 2-AAF is the inducer of DEN, and it is involved in tumour formation in the bladder and liver. Reactive Oxygen species (ROS); carbohydrates, lipids, DNA and enzymes, such as affect all important structures. Additionally, an excessive amount of ROS is highly toxic to cells. Antioxidants are protects against ROS, toxic substances, carcinogens. This review focuses on the literature on studies of Hepatic Carcinogenesis, oxidative stress and antioxidant therapy.

Inhibition and disaggregation of amyloid β protein fibrils through conjugated polymer–core thermoresponsive micelles

2020 ◽  
Vol 8 (44) ◽  
pp. 10126-10135
Author(s):  
Hao Geng ◽  
Hongbo Yuan ◽  
Liang Qiu ◽  
Dong Gao ◽  
Yongqiang Cheng ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
White Light ◽  
Conjugated Polymer ◽  
Amyloid Β ◽  
Reactive Oxygen ◽  
Light Irradiation ◽  
Amyloid Β Protein ◽  
Oxygen Species ◽  
Β Protein ◽  
Protein Fibrils

The micelles (CPMs) have a thermoresponsive surface and reactive oxygen species (ROS) generating core. At 37 °C, CPMs captured Aβ aggregates to inhibit and disaggregate aggregates under white-light irradiation, reducing Aβ-induced cytotoxicity.

Fabrication of magnetic BaFe12O19/Ag3PO4 composites with an in situ photo-Fenton-like reaction for enhancing reactive oxygen species under visible light irradiation

2019 ◽  
Vol 9 (10) ◽  
pp. 2563-2570 ◽  
Author(s):  
Yuanguo Xu ◽  
Feiyue Ge ◽  
Meng Xie ◽  
Shuquan Huang ◽  
Junchao Qian ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Reactive Oxygen ◽  
Light Irradiation ◽  
Oh Radicals ◽  
Oxygen Species

An in situ photo-Fenton-like and magnetic recycle system, BaFe12O19/Ag3PO4 has been constructed. BaFe12O19 can catalyze the conversion of H2O2 to generate ROSs (˙O2− and ˙OH radicals) on the surface of Ag3PO4.

scholarly journals The Synthesis of Ascorbic Acid in Rice Roots Plays an Important Role in the Salt Tolerance of Rice by Scavenging ROS

2018 ◽  
Vol 19 (11) ◽  
pp. 3347 ◽  
Author(s):  
Yayun Wang ◽  
Hui Zhao ◽  
Hua Qin ◽  
Zixuan Li ◽  
Hai Liu ◽  
...  
Keyword(s):  
Reactive Oxygen Species ◽  
Ascorbic Acid ◽  
Salt Stress ◽  
Salt Tolerance ◽  
Stress Responses ◽  
Reactive Oxygen ◽  
Oxygen Species ◽  
Rice Roots ◽  
Key Factor ◽  
Rna Interfering

The root plays an important role in the responses of plants to stresses, but the detailed mechanisms of roots in stress responses are still obscure. The GDP-mannose pyrophosphate synthetase (GMPase) OsVTC1-3 is a key factor of ascorbic acid (AsA) synthesis in rice roots. The present study showed that the transcript of OsVTC1-3 was induced by salt stress in roots, but not in leaves. Inhibiting the expression of OsVTC1-3 by RNA interfering (RI) technology significantly impaired the tolerance of rice to salt stress. The roots of OsVTC1-3 RI plants rapidly produced more O2−, and later accumulated amounts of H2O2 under salt stress, indicating the impaired tolerance of OsVTC1-3 RI plants to salt stress due to the decreasing ability of scavenging reactive oxygen species (ROS). Moreover, exogenous AsA restored the salt tolerance of OsVTC1-3 RI plants, indicating that the AsA synthesis in rice roots is an important factor for the response of rice to salt stress. Further studies showed that the salt-induced AsA synthesis was limited in the roots of OsVTC1-3 RI plants. The above results showed that specifically regulating AsA synthesis to scavenge ROS in rice roots was one of important factors in enhancing the tolerance of rice to salt stress.

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