Spatiotemporal regulation of dynamic cell microenvironment signals based on an azobenzene photoswitch

2020 ◽  
Vol 8 (40) ◽  
pp. 9212-9226
Author(s):  
Kai Wu ◽  
Jing Sun ◽  
Yanzhe Ma ◽  
Dan Wei ◽  
Oscar Lee ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Tissue Engineering Scaffolds ◽  
Cell Microenvironment ◽  
Cell Material ◽  
Spatiotemporal Regulation ◽  
Dynamic Cell ◽  
Cell Material Interactions

Photoisomerization and red-shifted photoswitching make azobenzene superior for exploring the cell-material interactions and designing tissue-engineering scaffolds.

Evaluation of Cell-Material Interactions on Newly Designed, Printable Polymers for Tissue Engineering Applications

2011 ◽  
Vol 13 (12) ◽  
pp. B467-B475 ◽  
Author(s):  
Esther C. Novosel ◽  
Wolfdietrich Meyer ◽  
Nadine Klechowitz ◽  
Hartmut Krüger ◽  
Michael Wegener ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Engineering Applications ◽  
Cell Material ◽  
Cell Material Interactions

Bioactivated protein-based porous microcarriers for tissue engineering applications

2014 ◽  
Vol 2 (44) ◽  
pp. 7795-7803 ◽  
Author(s):  
Baiwen Luo ◽  
Qiu Li Loh ◽  
Marcus Thien Chong Wong ◽  
Nguan Soon Tan ◽  
Cleo Choong
Keyword(s):  
Tissue Engineering ◽  
Extracellular Matrix ◽  
Cell Adhesion ◽  
Biological Factors ◽  
Adhesion Receptors ◽  
Engineering Applications ◽  
Cell Material ◽  
Cell Material Interactions

Lipoaspirate-derived extracellular matrix enrichment was able to provide the necessary cell adhesion receptors and biological factors for improving cell–material interactions of porous OVA microcarriers.

scholarly journals Nanoscale investigation in 3D scaffolds of cell-material interactions for tissue-engineering

2018 ◽  
Author(s):  
Donata Iandolo ◽  
Fabrizio A. Pennacchio ◽  
Valentina Mollo ◽  
Domenico Rossi ◽  
David Dannhauser ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Fate ◽  
3D Models ◽  
Cellular Adhesion ◽  
3D Scaffolds ◽  
Cell Material ◽  
Guidance Strategies ◽  
Cell Material Interactions

AbstractCell fate is largely determined by interactions that occur at the interface between cells and their surrounding microenvironment. For this reason, especially in the field of cell- and tissue-engineering, there is a growing interest in developing characterization techniques that allow a deep evaluation of cell-material interaction at the nanoscale, particularly focusing on cell adhesion processes. While for 2D culturing systems a consolidated series of tools already satisfy this need, in 3D environments, more closely recapitulating complex in vivo structures, there is still a lack of procedure furthering the comprehension of cell-material interactions. Here, we report for the first time the use of a SEM/FIB system for the characterization of cellular adhesion in 3D scaffolds fabricated by means of different techniques. Our results clearly show the capability of the developed approach to finely resolve both scaffold-cells interface and nanometer scale features of cell bodies involved in the upregulation of cellular behavior. These results are relevant for studying cellular guidance strategies and for the consequent design of more efficient cell-instructive platforms for tissue-engineering applications as well as for in vitro 3D models.

Orchestrating Cell/Material Interactions For Tissue Engineering of Surgical Implants

2012 ◽  
Vol 12 (8) ◽  
pp. 1010-1021 ◽  
Author(s):  
Achala de Mel ◽  
Alexander M. Seifalian ◽  
Martin A. Birchall
Keyword(s):  
Tissue Engineering ◽  
Cell Material ◽  
Surgical Implants ◽  
Cell Material Interactions

scholarly journals Cell Microenvironment Engineering and Monitoring for Tissue Engineering and Regenerative Medicine: The Recent Advances

2014 ◽  
Vol 2014 ◽  
pp. 1-18 ◽  
Author(s):  
Julien Barthes ◽  
Hayriye Özçelik ◽  
Mathilde Hindié ◽  
Albana Ndreu-Halili ◽  
Anwarul Hasan ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Regenerative Medicine ◽  
Control Cell ◽  
Matrix Composition ◽  
Tissue Engineering Scaffolds ◽  
Cell Microenvironment ◽  
Engineered Tissues ◽  
Cellular Behaviour

In tissue engineering and regenerative medicine, the conditions in the immediate vicinity of the cells have a direct effect on cells’ behaviour and subsequently on clinical outcomes. Physical, chemical, and biological control of cell microenvironment are of crucial importance for the ability to direct and control cell behaviour in 3-dimensional tissue engineering scaffolds spatially and temporally. In this review, we will focus on the different aspects of cell microenvironment such as surface micro-, nanotopography, extracellular matrix composition and distribution, controlled release of soluble factors, and mechanical stress/strain conditions and how these aspects and their interactions can be used to achieve a higher degree of control over cellular activities. The effect of these parameters on the cellular behaviour within tissue engineering context is discussed and how these parameters are used to develop engineered tissues is elaborated. Also, recent techniques developed for the monitoring of the cell microenvironmentin vitroandin vivoare reviewed, together with recent tissue engineering applications where the control of cell microenvironment has been exploited. Cell microenvironment engineering and monitoring are crucial parts of tissue engineering efforts and systems which utilize different components of the cell microenvironment simultaneously can provide more functional engineered tissues in the near future.

Cell-material interactions in tendon tissue engineering

2018 ◽  
Vol 70 ◽  
pp. 1-11 ◽  
Author(s):  
Junxin Lin ◽  
Wenyan Zhou ◽  
Shan Han ◽  
Varitsara Bunpetch ◽  
Kun Zhao ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Tendon Tissue ◽  
Cell Material ◽  
Tendon Tissue Engineering ◽  
Cell Material Interactions

Does the tissue engineering architecture of poly(3-hydroxybutyrate) scaffold affects cell-material interactions?

2012 ◽  
Vol 100A (7) ◽  
pp. 1907-1918 ◽  
Author(s):  
Elahe Masaeli ◽  
Mohammad Morshed ◽  
Parsa Rasekhian ◽  
Saeed Karbasi ◽  
Khadije Karbalaie ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Material ◽  
Cell Material Interactions

Novel tissue engineering scaffolds as wound dressings loaded with Alkannins/Shikonins as active ingredients

2019 ◽  
Author(s):  
AS Arampatzis ◽  
K Theodoridis ◽  
E Aggelidou ◽  
KN Kontogiannopoulos ◽  
I Tsivintzelis ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Wound Dressings ◽  
Active Ingredients ◽  
Tissue Engineering Scaffolds

HYDROXYAPATITE, ALGINATE, AND CHITOSAN FOR BONE SCAFFOLDS: SPECTROSCOPY STUDY

2016 ◽  
Vol 19 (2) ◽  
pp. 93-100
Author(s):  
Lalita El Milla
Keyword(s):  
Tissue Engineering ◽  
Bone Tissue Engineering ◽  
Bone Tissue ◽  
Functional Groups ◽  
Bone Growth ◽  
Three Dimensional ◽  
Dimensional Structure ◽  
Tissue Engineering Scaffolds ◽  
Hydroxyapatite Powder ◽  
Materials Used

Scaffolds is three dimensional structure that serves as a framework for bone growth. Natural materials are often used in synthesis of bone tissue engineering scaffolds with respect to compliance with the content of the human body. Among the materials used to make scafffold was hydroxyapatite, alginate and chitosan. Hydroxyapatite powder obtained by mixing phosphoric acid and calcium hydroxide, alginate powders extracted from brown algae and chitosan powder acetylated from crab. The purpose of this study was to examine the functional groups of hydroxyapatite, alginate and chitosan. The method used in this study was laboratory experimental using Fourier Transform Infrared (FTIR) spectroscopy for hydroxyapatite, alginate and chitosan powders. The results indicated the presence of functional groups PO43-, O-H and CO32- in hydroxyapatite. In alginate there were O-H, C=O, COOH and C-O-C functional groups, whereas in chitosan there were O-H, N-H, C=O, C-N, and C-O-C. It was concluded that the third material containing functional groups as found in humans that correspond to the scaffolds material in bone tissue engineering.

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