Recent advances of polyoxometalates in multi-functional imaging and photothermal therapy

2020 ◽  
Vol 8 (36) ◽  
pp. 8189-8206 ◽  
Author(s):  
Xueping Kong ◽  
Guofeng Wan ◽  
Bao Li ◽  
Lixin Wu
Keyword(s):  
Functional Imaging ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Imaging Techniques ◽  
Tumor Therapy ◽  
Recent Advances ◽  
Bio Imaging

The recent advances of polyoxometalate clusters in terms of near infrared photothermal properties for targeted tumor therapy have been summarized while the combined applications with various bio-imaging techniques and chemotherapies are reviewed.

Recent Advances of Red/Near Infrared Light Responsive Carbon Dots for Tumor Therapy

2021 ◽  
Vol 42 (08) ◽  
pp. 1155-1171
Author(s):  
Fu-chun NAN ◽  
◽  
Xiao-kuang XUE ◽  
Jie-chao GE ◽  
Peng-fei WANG ◽  
...  
Keyword(s):  
Carbon Dots ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Recent Advances

scholarly journals Therapeutic nanodendrites: current applications and prospects

2020 ◽  
Vol 2 (11) ◽  
pp. 5152-5165
Author(s):  
Adewale O. Oladipo ◽  
Thabo T. I. Nkambule ◽  
Bhekie B. Mamba ◽  
Titus A. M. Msagati
Keyword(s):  
Drug Delivery ◽  
Photothermal Therapy ◽  
Recent Advances ◽  
Bio Imaging

This minireview highlights recent advances in the synthesis and applications of metallic nanodendrites for bio-imaging, drug delivery, photothermal therapy, and radiotherapy.

Near-infrared-II Light Excitation Thermosensitive Liposomes for Photoacoustic Imaging Guided and Enhanced Photothermal-Chemo Synergistic Tumor Therapy

2021 ◽  
Author(s):  
Yeneng Dai ◽  
Wenyu Du ◽  
Diya Gao ◽  
Haowei Zhu ◽  
Fan Zhang ◽  
...  
Keyword(s):  
Penetration Depth ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Photoacoustic Imaging ◽  
Tumor Therapy ◽  
Great Success ◽  
Light Excitation ◽  
Thermosensitive Liposomes

Although the great success of photothermal therapy (PTT), it still suffers from many obstacles, such as the limited penetration depth of light, thermoresistance of tumor, as well as the limitations...

Target-specific induced hyaluronic acid decorated silica fluorescent nanoparticles@polyaniline for bio-imaging guided near-infrared photothermal therapy

2017 ◽  
Vol 5 (34) ◽  
pp. 7099-7108 ◽  
Author(s):  
Zihnil Adha Islamy Mazrad ◽  
Cheong A Choi ◽  
Sung Han Kim ◽  
Gibaek Lee ◽  
Sangkug Lee ◽  
...  
Keyword(s):  
Hyaluronic Acid ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Fluorescent Nanoparticles ◽  
Treatment Progress ◽  
Bio Imaging

Heating properties of FNPs(Si/HA)@PANI nanoparticles could lead to new options for photothermal therapy guided by tumor targeted bioimaging to track treatment progress.

scholarly journals Double Drug-Loaded and pH/Thermal Sensitive Multifunctional Drug Delivery System for Tumor Photoacoustic Imaging-Guided Enhanced Chemo/Photothermal Therapy

2019 ◽  
Author(s):  
Jun Wang ◽  
Na Chen ◽  
Kai Liu ◽  
Yu Tu ◽  
Weitao Yang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Drug Delivery System ◽  
Delivery System ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Drug Loading ◽  
Tumor Therapy ◽  
Photothermal Effect ◽  
Heterogeneous Distribution

Abstract Background: Owing to the tunability of longitudinal surface plasmon resonance (LSPR), ease of synthesizing small size and excellent stability, AuNRs have been developed as photothermal agents for cancer therapy. However, PTT alone could not kill cancer cells completely due to the local heterogeneous distribution of heat in tumors, penetration depth of light, light scattering and absorption. In addition, the treatment systems based on AuNRs hold disadvantages of loading one antitumor drug or a low therapeutic efficiency. Therefore, the construction of the AuNRs theranostic system to achieve imaging-guided dual drug delivery and enhanced photothermal therapy for tumor still remains a great challenge.Methods: The AuNRs were prepared using a seedless method. A mesoporous silica shell layer was coated on the surface of the AuNRs by sol-gel method. Double anticancer drugs, DOX and Btz, were loaded into the AuNRs@MSN nanoparticles through physical absorption and covalent conjugation, respectively.Results: The release of DOX and Btz is found pH/thermal dual responsive in vitro. Compared with AuNRs@MSN, PDA-AuNRs@MSN exhibits an increased near-infrared (NIR) absorption at 808 nm and an enhanced photothermal effect. In contrast to chemotherapy or photothermal therapy alone, the integrated D/B-PDA-AuNRs@MSN nanoparticles show higher cell apoptosis and enhanced tumor treatment efficacy in vitro and in vivo.Conclusions: In this study, we designed a double-drug loading, enhanced chemo/photothermal therapy and pH/thermal responsive drug delivery system for photoacoustic (PA) imaging-guided tumor therapy. We believe that the multifunctional D/B-PDA-AuNRs@MSN theranostic probe could serve as an effective probe for the treatment of cancers.

Multimodal imaging and photothermal therapy were simultaneously achieved in the core–shell UCNR structure by using single near-infrared light

2017 ◽  
Vol 46 (36) ◽  
pp. 12147-12157 ◽  
Author(s):  
Chen Wang ◽  
Liangge Xu ◽  
Jiating Xu ◽  
Dan Yang ◽  
Bin Liu ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Multimodal Imaging ◽  
Near Infrared ◽  
Infrared Light ◽  
Upconversion Nanoparticles ◽  
Core Shell ◽  
Imaging Diagnosis ◽  
The Core ◽  
Shell Nanostructures ◽  
Bio Imaging

Core–shell nanostructures consisting of plasmonic materials and lanthanide-doped upconversion nanoparticles (UCNPs) show promising applications in theranostics including bio-imaging, diagnosis and therapy.

scholarly journals Photothermal Therapy for the Treatment of Glioblastoma: Potential and Preclinical Challenges

2021 ◽  
Vol 10 ◽  
Author(s):  
Chiara Bastiancich ◽  
Anabela Da Silva ◽  
Marie-Anne Estève
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Imaging Techniques ◽  
Resistance Mechanisms ◽  
Infrared Light ◽  
Tumor Site ◽  
Distinctive Features ◽  
Power Intensity ◽  
Medical Need ◽  
Conventional Drug

Glioblastoma (GBM) is a very aggressive primary malignant brain tumor and finding effective therapies is a pharmaceutical challenge and an unmet medical need. Photothermal therapy may be a promising strategy for the treatment of GBM, as it allows the destruction of the tumor using heat as a non-chemical treatment for disease bypassing the GBM heterogeneity limitations, conventional drug resistance mechanisms and side effects on peripheral healthy tissues. However, its development is hampered by the distinctive features of this tumor. Photoabsorbing agents such as nanoparticles need to reach the tumor site at therapeutic concentrations, crossing the blood-brain barrier upon systemic administration. Subsequently, a near infrared light irradiating the head must cross multiple barriers to reach the tumor site without causing any local damage. Its power intensity needs to be within the safety limit and its penetration depth should be sufficient to induce deep and localized hyperthermia and achieve tumor destruction. To properly monitor the therapy, imaging techniques that can accurately measure the increase in temperature within the brain must be used. In this review, we report and discuss recent advances in nanoparticle-mediated plasmonic photothermal therapy for GBM treatment and discuss the preclinical challenges commonly faced by researchers to develop and test such systems.

Dual-targeted and MRI-guided photothermal therapy via iron-based nanoparticles-incorporated neutrophils

2021 ◽  
Author(s):  
Jing Wang ◽  
Tianxiao Mei ◽  
Yang Liu ◽  
Yifan Zhang ◽  
Ziliang Zhang ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Therapy ◽  
Local Temperature ◽  
Tumor Site ◽  
Mri Guided ◽  
Iron Based

Nanoparticle-mediated photothermal therapy (PTT) has shown the promising capability for tumor therapy through the high local temperature at the tumor site generated by photothermal agent (PTA) under visible or near-infrared...

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