Photoswitchable dynasore analogs to control endocytosis with light

Núria Camarero; Ana Trapero; Ariadna Pérez-Jiménez; Eric Macia; Alexandre Gomila-Juaneda; Andrés Martín-Quirós; Laura Nevola; Artur Llobet; Amadeu Llebaria; Jordi Hernando; Ernest Giralt; Pau Gorostiza

doi:10.1039/d0sc03820b

Photoswitchable dynasore analogs to control endocytosis with light

Chemical Science ◽

10.1039/d0sc03820b ◽

2020 ◽

Vol 11 (33) ◽

pp. 8981-8988

Author(s):

Núria Camarero ◽

Ana Trapero ◽

Ariadna Pérez-Jiménez ◽

Eric Macia ◽

Alexandre Gomila-Juaneda ◽

...

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Pharmacological Properties ◽

Photochromic Properties ◽

Molecule Inhibitor ◽

Azobenzene Group

We've combined the pharmacological properties of the dynamin inhibitor dynasore and the photochromic properties of an azobenzene group, to obtain the first light-regulated small-molecule inhibitor of endocytosis.

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2004 ◽

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Shh Pathway ◽

Molecule Inhibitor

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2005 ◽

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Atm Kinase ◽

Molecule Inhibitor ◽

Hiv 1

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2006 ◽

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Bi 2536

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2007 ◽

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor ◽

Bi 2536

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Keyword(s):

Small Molecule ◽

Small Molecule Inhibitor ◽

Actin Assembly ◽

Molecule Inhibitor ◽

Identification And Characterization

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Daniel G Gioeli

Keyword(s):

Prostate Cancer ◽

Androgen Receptor ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Amino Terminus ◽

Recurrent Prostate Cancer ◽

Molecule Inhibitor

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Jeffrey Hannah

Keyword(s):

Multiple Myeloma ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Myeloma Cells ◽

Molecule Inhibitor ◽

Specific Protease ◽

Ubiquitin Specific Protease

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Author(s):

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Keyword(s):

Small Molecule ◽

Tumor Regression ◽

Small Molecule Inhibitor ◽

Complete Tumor Regression ◽

Molecule Inhibitor ◽

Complete Tumor

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Keyword(s):

Hypertrophic Cardiomyopathy ◽

Small Molecule ◽

Small Molecule Inhibitor ◽

Molecule Inhibitor

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