scholarly journals Continuous one-flow multi-step synthesis of active pharmaceutical ingredients

2020 ◽  
Vol 5 (7) ◽  
pp. 1186-1197 ◽  
Author(s):  
Victor R. L. J. Bloemendal ◽  
Mathilde A. C. H. Janssen ◽  
Jan C. M. van Hest ◽  
Floris P. J. T. Rutjes
Keyword(s):  
Continuous Flow ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Flow Processes ◽  
Selection Of

This review highlights a selection of multistep continuous flow (one-flow) processes leading to the synthesis of active pharmaceutical ingredients (APIs).

Towards 4th industrial revolution efficient and sustainable continuous flow manufacturing of active pharmaceutical ingredients

2022 ◽  
Author(s):  
Cloudius Sagandira ◽  
Sinazo Nqeketo ◽  
Kanysile Mhlana ◽  
Thembela Sonti ◽  
Paul Watts ◽  
...  
Keyword(s):  
Pharmaceutical Industry ◽  
Continuous Flow ◽  
Industrial Revolution ◽  
Flow Chemistry ◽  
Active Pharmaceutical Ingredients ◽  
New Paradigm ◽  
Pharmaceutical Ingredients ◽  
Continuous Flow Chemistry

Continuous flow chemistry has opened a new paradigm in both the laboratory and pharmaceutical industry. This review details the recently reported literature on continuous multistep telescoped synthesis of active pharmaceutical...

Evolution of flow-oriented design strategies in the continuous preparation of pharmaceuticals

2020 ◽  
Vol 5 (9) ◽  
pp. 1527-1555 ◽  
Author(s):  
Zsolt Fülöp ◽  
Péter Szemesi ◽  
Péter Bana ◽  
János Éles ◽  
István Greiner
Keyword(s):  
Continuous Flow ◽  
Active Pharmaceutical Ingredients ◽  
Design Strategies ◽  
Flow Synthesis ◽  
Pharmaceutical Ingredients ◽  
Continuous Preparation

This review focuses on the flow-oriented design (FOD) in the multi-step continuous-flow synthesis of active pharmaceutical ingredients.

Continuous flow upgrading of glycerol toward oxiranes and active pharmaceutical ingredients thereof

2019 ◽  
Vol 21 (16) ◽  
pp. 4422-4433 ◽  
Author(s):  
Romain Morodo ◽  
Romaric Gérardy ◽  
Guillaume Petit ◽  
Jean-Christophe M. Monbaliu
Keyword(s):  
Amino Alcohol ◽  
Continuous Flow ◽  
Value Added ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients

A robust continuous flow procedure for the transformation of bio-based glycerol into high value-added β-amino alcohol active pharmaceutical ingredients.

scholarly journals The A Priori Design and Selection of Ionic Liquids as Solvents for Active Pharmaceutical Ingredients

2017 ◽  
Vol 23 (23) ◽  
pp. 5498-5508 ◽  
Author(s):  
Andreas J. Kunov‐Kruse ◽  
Cameron C. Weber ◽  
Robin D. Rogers ◽  
Allan S. Myerson
Keyword(s):  
Ionic Liquids ◽  
A Priori ◽  
Active Pharmaceutical Ingredients ◽  
Pharmaceutical Ingredients ◽  
Selection Of
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