scholarly journals Fabrication of TiO2 microspikes for highly efficient intracellular delivery by pulse laser-assisted photoporation

RSC Advances ◽  
2021 ◽  
Vol 11 (16) ◽  
pp. 9336-9348
Author(s):  
L. Mohan ◽  
Srabani Kar ◽  
Pallab Sinha Mahapatra ◽  
Moeto Nagai ◽  
Tuhin Subhra Santra
Keyword(s):  
Cell Viability ◽  
Pulse Laser ◽  
Intracellular Delivery ◽  
Living Cells ◽  
Highly Efficient ◽  
Delivery Efficiency

The introduction of foreign cargo into living cells with high delivery efficiency and cell viability by laser asisted photoporation on TiO2 microspikes platform.

Infrared Pulse Laser-Activated Highly Efficient Intracellular Delivery Using Titanium Microdish Device

2020 ◽  
Vol 6 (10) ◽  
pp. 5645-5652 ◽  
Author(s):  
Pallavi Shinde ◽  
Srabani Kar ◽  
Mohan Loganathan ◽  
Hwan-You Chang ◽  
Fan-Gang Tseng ◽  
...  
Keyword(s):  
Pulse Laser ◽  
Intracellular Delivery ◽  
Highly Efficient

Near-infrared nanosecond-pulsed laser-activated highly efficient intracellular delivery mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles

Nanoscale ◽  
2020 ◽  
Vol 12 (22) ◽  
pp. 12057-12067 ◽  
Author(s):  
Tuhin Subhra Santra ◽  
Srabani Kar ◽  
Te-Chang Chen ◽  
Chih-Wei Chen ◽  
Jayant Borana ◽  
...  
Keyword(s):  
Cell Viability ◽  
Near Infrared ◽  
Pulsed Laser ◽  
Intracellular Delivery ◽  
High Cell ◽  
Polystyrene Nanoparticles ◽  
Infrared Wavelength ◽  
Highly Efficient ◽  
Nanosecond Pulsed Laser

Here, an efficient intracellular delivery of molecules with high cell viability is reported using plasmonic photoporation mediated by nano-corrugated mushroom-shaped gold-coated polystyrene nanoparticles at near-infrared wavelength.

Nano-localized single-cell nano-electroporation

Lab on a Chip ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 4194-4204
Author(s):  
Tuhin Subhra Santra ◽  
Srabani Kar ◽  
Hwan-You Chang ◽  
Fan-Gang Tseng
Keyword(s):  
Cell Viability ◽  
Single Cell ◽  
Intracellular Delivery ◽  
High Cell ◽  
Highly Efficient

We demonstrated nano-electroporation technique to create transient nano-holes at single or multiple nano-localized positions of a single-cell for a highly efficient intracellular delivery with high cell viability.

Probing Cellular Outcomes Using Heterobivalent Constructs

2019 ◽  
Author(s):  
Rohit Bhadoria ◽  
Kefeng Ping ◽  
Christer Lohk ◽  
Ivar Järving ◽  
Pavel Starkov
Keyword(s):  
Cell Viability ◽  
Small Molecules ◽  
Cellular Uptake ◽  
Kinase Inhibitors ◽  
Rho Kinase ◽  
Intracellular Delivery ◽  
Rho Kinase Inhibitors

<div> <div> <div> <p>Conjugation techniques are central to improving intracellular delivery of bioactive small molecules. However, tracking and assessing the overall biological outcome of these constructs remains poorly understood. We addressed this issue by having developed a focused library of heterobivalent constructs based on Rho kinase inhibitors to probe various scenarios. By comparing induction of a phenotype of interest vs. cell viability vs. cellular uptake, we demonstrate that such conjugates indeed lead to divergent cellular outcomes. </p> </div> </div> </div>

Lipo-Poly(L-histidine) Hybrid Materials with pH-Sensitivity, Intracellular Delivery Efficiency, and Intrinsic Targetability to Cancer Cells

2014 ◽  
Vol 35 (9) ◽  
pp. 888-894 ◽  
Author(s):  
Renjith P. Johnson ◽  
Young-Il Jeong ◽  
Johnson V. John ◽  
Chung-Wook Chung ◽  
Seon Hee Choi ◽  
...  
Keyword(s):  
Cancer Cells ◽  
Hybrid Materials ◽  
Intracellular Delivery ◽  
Ph Sensitivity ◽  
Delivery Efficiency

scholarly journals Tetra-fluorinated aromatic azide for highly efficient bioconjugation in living cells

RSC Advances ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 23-26 ◽  
Author(s):  
Xuekang Cai ◽  
Dan Wang ◽  
Yasi Gao ◽  
Long Yi ◽  
Xing Yang ◽  
...  
Keyword(s):  
High Efficiency ◽  
Living Cells ◽  
Highly Efficient ◽  
Aromatic Azide

A fast strain-promoted azide–alkyne cycloaddition based on tetra-fluorinated aromatic azide was developed and applied to label proteins and living cells with high efficiency.

Sensitive and sustained imaging of intracellular microRNA in living cells by a high biocompatible liposomal vehicle introduced isothermal symmetric exponential amplification reaction

2019 ◽  
Vol 55 (75) ◽  
pp. 11251-11254 ◽  
Author(s):  
Wen Yin ◽  
Jun Chen ◽  
Huihui Yang ◽  
Yanfei Zhang ◽  
Zong Dai ◽  
...  
Keyword(s):  
Living Cells ◽  
Highly Efficient ◽  
Amplification Reaction

A biocompatible liposome was fabricated to introduce highly efficient oligonucleotide amplification in living cells for the sensitive and sustained imaging of microRNA.

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