scholarly journals Insulin amyloid polymorphs: implications for iatrogenic cytotoxicity

RSC Advances ◽  
2020 ◽  
Vol 10 (62) ◽  
pp. 37721-37727 ◽  
Author(s):  
Keisuke Yuzu ◽  
Mikael Lindgren ◽  
Sofie Nyström ◽  
Jun Zhang ◽  
Wakako Mori ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Structural Polymorphism

Structural polymorphism of insulin amyloids in vivo can be recognized using novel amyloid specific fluorescent probes, pFTAA and BTD21.

scholarly journals Polarity-active NIR probes with strong two-photon absorption and ultrahigh binding affinity of insulin amyloid fibrils

2021 ◽  
Author(s):  
Li Li ◽  
Zheng Lv ◽  
Zhongwei Man ◽  
Zhenzhen Xu ◽  
YuLing Wei ◽  
...  
Keyword(s):  
Neurodegenerative Diseases ◽  
Binding Affinity ◽  
Fluorescent Probes ◽  
Amyloid Fibrils ◽  
Photon Absorption ◽  
Two Photon Absorption ◽  
Two Photon ◽  
Medical Diagnostic

Amyloid fibrils are associated with many neurodegenerative diseases. In-situ and in-vivo visualization of amyloid fibrils is important for medical diagnostic and requires fluorescent probes with both excitation and emission wavelengths in...

scholarly journals Biological nanoscale fluorescent probes: From structure and performance to bioimaging

2020 ◽  
Vol 39 (1) ◽  
pp. 209-221
Author(s):  
Jiafeng Wan ◽  
Xiaoyuan Zhang ◽  
Kai Zhang ◽  
Zhiqiang Su
Keyword(s):  
Fluorescent Probes ◽  
Organic Dyes ◽  
Resonance Energy Transfer ◽  
Resonance Energy ◽  
High Sensitivity ◽  
Biological Imaging ◽  
Fluorescent Materials ◽  
And Performance

Abstract In recent years, nanomaterials have attracted lots of attention from researchers due to their unique properties. Nanometer fluorescent materials, such as organic dyes, semiconductor quantum dots (QDs), metal nano-clusters (MNCs), carbon dots (CDs), etc., are widely used in biological imaging due to their high sensitivity, short response time, and excellent accuracy. Nanometer fluorescent probes can not only perform in vitro imaging of organisms but also achieve in vivo imaging. This provides medical staff with great convenience in cancer treatment. Combined with contemporary medical methods, faster and more effective treatment of cancer is achievable. This article explains the response mechanism of three-nanometer fluorescent probes: the principle of induced electron transfer (PET), the principle of fluorescence resonance energy transfer (FRET), and the principle of intramolecular charge transfer (ICT), showing the semiconductor QDs, precious MNCs, and CDs. The excellent performance of the three kinds of nano fluorescent materials in biological imaging is highlighted, and the application of these three kinds of nano fluorescent probes in targeted biological imaging is also introduced. Nanometer fluorescent materials will show their significance in the field of biomedicine.

scholarly journals In vivo visualization of osteoarthritic hypertrophic lesions

2015 ◽  
Vol 6 (11) ◽  
pp. 6256-6261 ◽  
Author(s):  
Hai-Yu Hu ◽  
Ngee-Han Lim ◽  
Hans-Paul Juretschke ◽  
Danping Ding-Pfennigdorff ◽  
Peter Florian ◽  
...  
Keyword(s):  
Animal Models ◽  
Fluorescent Probes

Cartilage-binding bimodal MRI and fluorescent probes were developed to monitor osteoarthritic damage in animal models over extended periods of time.

Design of Bis-spiropyran Ligands as Dipolar Molecule Receptors and Application to in Vivo Glutathione Fluorescent Probes

2010 ◽  
Vol 132 (2) ◽  
pp. 725-736 ◽  
Author(s):  
Na Shao ◽  
Jianyu Jin ◽  
Hao Wang ◽  
Jing Zheng ◽  
Ronghua Yang ◽  
...  
Keyword(s):  
Fluorescent Probes ◽  
Dipolar Molecule

scholarly journals Fluorescent probes for in vivo redox potential measurement and thiol rich protein function

2006 ◽  
Vol 20 (4) ◽  
Author(s):  
Phani Kumar Pullela ◽  
Taurai Chiku ◽  
Michael J Carvan ◽  
Daniel S Sem
Keyword(s):  
Redox Potential ◽  
Fluorescent Probes ◽  
Protein Function ◽  
Potential Measurement

Realizing highly chemoselective detection of H2S in vitro and in vivo with fluorescent probes inside core-shell silica nanoparticles

Biomaterials ◽  
2018 ◽  
Vol 159 ◽  
pp. 82-90 ◽  
Author(s):  
Feiyi Wang ◽  
Ge Xu ◽  
Xianfeng Gu ◽  
Zhijun Wang ◽  
Zhiqiang Wang ◽  
...  
Keyword(s):  
Silica Nanoparticles ◽  
Fluorescent Probes ◽  
Core Shell

H2O2/HOCl-based fluorescent probes for dynamically monitoring pathophysiological processes

The Analyst ◽  
2020 ◽  
Vol 145 (23) ◽  
pp. 7477-7487
Author(s):  
Dan Zhang ◽  
Shaobo Guo ◽  
Le Li ◽  
Kun Shang
Keyword(s):  
Fluorescent Probes

H2O2/HOCl-based fluorescent probes for dynamically monitoring pathophysiological processes in vivo were described.

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