scholarly journals Effects of amino acids on conversion of calcium carbonate to hydroxyapatite

RSC Advances ◽  
2020 ◽  
Vol 10 (61) ◽  
pp. 37005-37013
Author(s):  
Sun Yanyan ◽  
Wang Guangxin ◽  
Sun Guoqing ◽  
Wang Yaming ◽  
Li Wuhui ◽  
...  

Conversion of calcium carbonate (calcite; CC) to hydroxyapatite (HAp) was examined when the CC particles of sub μm size were soaked at 37 °C for up to 10 d in 0.15 M K2HPO4 (20 ml), whose pH was set to 3–12.

Author(s):  
D. V. Lopatik ◽  
U. D. Kovalenko ◽  
Z. I. Kuvaeva ◽  
E. A. Manchik

Results of the study of the drug from calcium salts of amino acids (calcium diglycinate, calcium di-L-prolinate) on the model of osteoporosis in animals are described. The test substance was found to have better therapeutic effect in the regeneration of bone tissue in comparison with the drug containing calcium carbonate. The drug containing calcium salts of glycine and L-proline can be used for prevention and treatment of osteoporosis.


2018 ◽  
Vol 486 ◽  
pp. 71-81 ◽  
Author(s):  
Lara Štajner ◽  
Jasminka Kontrec ◽  
Branka Njegić Džakula ◽  
Nadica Maltar-Strmečki ◽  
Milivoj Plodinec ◽  
...  

1957 ◽  
Vol 3 (2) ◽  
pp. 165-169 ◽  
Author(s):  
A. C. Blackwood ◽  
A. C. Neish

Pseudomonas aeruginosa was grown under conditions suitable for pyocyanine production in a medium containing glycerol, L-leucine, DL-alanine, calcium carbonate, salts, and small amounts of various C14-labelled substrates. A comparison of the specific activities of the cell carbon, respiratory carbon dioxide, and pyocyanine carbon showed that glycerol and dihydroxyacetone were the only substrates from which pyocyanine having a specific activity higher than the cell carbon was formed. Glucose, fructose, pyruvate, acetate, and the 13 amino acids tested were inferior in this respect. Alanine, leucine, isoleucine, and glycine were incorporated into pyocyanine more readily than the other amino acids. Phenylalanine and tyrosine, although possessing preformed rings, were poor precursors of pyocyanine and were oxidized more readily than they were assimilated. These results suggest that pyocyanine originates from trioses but gives little indication of the nature of the intermediates.


Author(s):  
CHENG-LI YAO ◽  
CHUN-XIA QI ◽  
JIN-MIAO ZHU ◽  
WANG-HUA XU

2017 ◽  
Vol 17 (11) ◽  
pp. 5811-5822 ◽  
Author(s):  
R. Innocenti Malini ◽  
A. R. Finney ◽  
S. A. Hall ◽  
C. L. Freeman ◽  
J. H. Harding

2012 ◽  
Vol 227 (11) ◽  
pp. 744-757 ◽  
Author(s):  
Andreas Picker ◽  
Matthias Kellermeier ◽  
Jong Seto ◽  
Denis Gebauer ◽  
Helmut Cölfen

Endocrinology ◽  
2003 ◽  
Vol 144 (8) ◽  
pp. 3287-3296 ◽  
Author(s):  
Yuichi Yaoi ◽  
Masakazu Suzuki ◽  
Hideaki Tomura ◽  
Yuichi Sasayama ◽  
Sakae Kikuyama ◽  
...  

Abstract Anuran amphibians have a special organ called the endolymphatic sac (ELS), containing many calcium carbonate crystals, which is believed to have a calcium storage function. The major protein of aragonitic otoconia, otoconin-22, which is considered to be involved in the formation of calcium carbonate crystals, has been purified from the saccule of the Xenopus inner ear. In this study, we cloned a cDNA encoding otoconin-22 from the cDNA library constructed for the paravertebral lime sac (PVLS) of the bullfrog, Rana catesbeiana, and sequenced it. The bullfrog otoconin-22 encoded a protein consisting of 147 amino acids, including a signal peptide of 20 amino acids. The protein had cysteine residues identical in a number and position to those conserved among the secretory phospholipase A2 family. The mRNA of bullfrog otoconin-22 was expressed in the ELS, including the PVLS and inner ear. This study also revealed the presence of calcitonin receptor-like protein in the ELS, with the putative seven-transmembrane domains of the G protein-coupled receptors. The ultimobranchialectomy induced a prominent decrease in the otoconin-22 mRNA levels of the bullfrog PVLS. Supplementation of the ultimobranchialectomized bullfrogs with synthetic salmon calcitonin elicited a significant increase in the mRNA levels of the sac. These findings suggest that calcitonin secreted from the ultimobranchial gland, regulates expression of bullfrog otoconin-22 mRNA via calcitonin receptor-like protein on the ELS, thereby stimulating the formation of calcium carbonate crystals in the lumen of the ELS.


2017 ◽  
Vol 8 (1) ◽  
Author(s):  
Wenge Jiang ◽  
Michael S. Pacella ◽  
Dimitra Athanasiadou ◽  
Valentin Nelea ◽  
Hojatollah Vali ◽  
...  

2016 ◽  
Vol 16 (9) ◽  
pp. 5174-5183 ◽  
Author(s):  
David C. Green ◽  
Johannes Ihli ◽  
Yi-Yeoun Kim ◽  
Samantha Y. Chong ◽  
Phillip A. Lee ◽  
...  

2000 ◽  
Vol 39 (Part 2, No. 10B) ◽  
pp. L1071-L1073 ◽  
Author(s):  
Ayako Kai ◽  
Toshikatsu Miki

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