scholarly journals Selective cytotoxic effect against the MDA-MB-468 breast cancer cell line of the antibacterial palindromic peptide derived from bovine lactoferricin

RSC Advances ◽  
2020 ◽  
Vol 10 (30) ◽  
pp. 17593-17601 ◽  
Author(s):  
Andrea Barragán-Cárdenas ◽  
Maribel Urrea-Pelayo ◽  
Víctor Alfonso Niño-Ramírez ◽  
Adriana Umaña-Pérez ◽  
Jean Paul Vernot ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Alanine Scanning ◽  
Bovine Lactoferricin

The cytotoxic effect against the breast cancer cell line MDA-MB-468 of the palindromic peptide LfcinB (21–25)Pal: 1RWQWRWQWR9 and its analogous peptides, obtained via alanine scanning, was evaluated.

scholarly journals The tetrameric peptide LfcinB (20–25)4 derived from bovine lactoferricin induces apoptosis in the MCF-7 breast cancer cell line

RSC Advances ◽  
2019 ◽  
Vol 9 (36) ◽  
pp. 20497-20504 ◽  
Author(s):  
Jorge Rodríguez Guerra ◽  
Andrea Barragán Cárdenas ◽  
Alejandra Ochoa-Zarzosa ◽  
Joel López Meza ◽  
Adriana Umaña Pérez ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Bovine Lactoferricin ◽  
Line P ◽  
Mcf 7

The cytotoxic effect of the tetrameric peptide LfcinB (20–25)4 against breast cancer cell line ATCC® HTB-22™ (MCF-7) was evaluated.

scholarly journals The Cytotoxic Effect of Hyssop Extract on Breast Cancer Cell Line

2019 ◽  
Vol 13 (7) ◽  
pp. 22-28
Author(s):  
Faranak Fallahian ◽  
Nafiseh Mahdavi ◽  
Mohammadreza Haeri ◽  
◽  
◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line

Characterization andin vitro cytotoxic effect of adriamycin conjugated monoclonal antibody prepared against breast cancer cell line

Breast Cancer ◽  
1997 ◽  
Vol 4 (2) ◽  
pp. 85-92
Author(s):  
Hisanori Ikegaki ◽  
Noriaki Ohuchi ◽  
Takashi Masuko ◽  
Shinya Suzuki ◽  
Yuko Harada ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Monoclonal Antibody ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Cytotoxic Effect ◽  
Cancer Cell Line

scholarly journals Cytotoxic Effect of Post-Purified Herceptin Conjugated Recombinant Diphtheria Toxin on Sk-Br-3 Breast Cancer Cell Line

2017 ◽  
Vol 1 (Supplementary 1) ◽  
pp. 0-0
Author(s):  
Sahel Amoozadeh ◽  
Mohammad Morad Farajollahi ◽  
Maryam Hemmati ◽  
Parastoo Tarighi
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Diphtheria Toxin ◽  
Cytotoxic Effect ◽  
Cancer Cell Line

RGD peptide-mediated liposomal curcumin targeted delivery to breast cancer cells

2020 ◽  
pp. 088532822094936
Author(s):  
Reza Mahmoudi ◽  
Seyedeh Ashraf Mirahmadi-Babaheidri ◽  
Hamdollah Delaviz ◽  
Mohamad Hassan Fouani ◽  
Mohsen Alipour ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cell Line ◽  
Cancer Cell ◽  
Breast Cancer Cell ◽  
Breast Cancer Cell Line ◽  
Targeted Delivery ◽  
Cytotoxic Effect ◽  
Cancer Cell Line ◽  
Control Group ◽  
Mcf 7

In this study, turmeric's active ingredient (Curcumin) was encapsulated into RGD modified Liposomes (RGD-Lip-Cur) its cytotoxic effect on the breast cancer cell line (MCF-7) was evaluated by MTT, flow cytometry and Caspase assay. Liposomes were characterized using transmission electron microscopy (TEM). Results demonstrated that the liposomes were spherical in shape, ranging from 70 to 100 nm. MTT assay revealed that RGD-Lip-Cur had a significant cytotoxic effect on MCF-7 cells at concentrations of 32, 16 and 4 μg/ml compared to Lip-Cur (P < 0.05) and curcumin (P < 0.01). The apoptosis assay demonstrated that RGD-Lip-Cur induces the apoptosis in MCF-7 cells (39.6% vs 40.2% for initial and secondary apoptosis) significantly more than Lip-Cur (67.7% vs 9.16% for initial and secondary apoptosis) and free curcumin (7.84% vs 38.8% for initial and secondary apoptosis). Moreover, caspase assay showed that RGD-Lip-Cur activates caspase 3/7 compared to Lip-Cur (P < 0.05) and free curcumin (P < 0.01). The RGD-Lip-Cur was similar to the control group and had no significant cytotoxicity effect. It is concluded that RGD-Lip-Cur as a novel carrier have high cytotoxicity effect on breast cancer cell line (MCF-7).

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