scholarly journals A facile, practical and metal-free microwave-assisted protocol for mono- and bis-[1,2,4]triazolo[1,5-a]pyridines synthesis utilizing 1-amino-2-imino-pyridine derivatives as versatile precursors

RSC Advances ◽  
2020 ◽  
Vol 10 (26) ◽  
pp. 15554-15572 ◽  
Author(s):  
Hamada Mohamed Ibrahim ◽  
Haider Behbehani ◽  
Wael Abdelgayed Ahmed Arafa
Keyword(s):  
Energy Source ◽  
Microwave Irradiation ◽  
Green Energy ◽  
Pyridine Derivatives ◽  
Metal Free ◽  
Microwave Assisted ◽  
Highly Efficient

A novel and highly efficient, protocol for synthesizing mono- and bis-[1,2,4]triazolo[1,5-a]pyridines has been established utilizing the readily attainable 1-amino-2-imino-pyridines and microwave irradiation as green energy source.

scholarly journals On water catalyst-free synthesis of benzo[d]imidazo[2,1-b] thiazoles and novel N-alkylated 2-aminobenzo[d]oxazoles under microwave irradiation

RSC Advances ◽  
2020 ◽  
Vol 10 (2) ◽  
pp. 770-778 ◽  
Author(s):  
Narasimharao Mukku ◽  
Barnali Maiti
Keyword(s):  
Microwave Irradiation ◽  
Microwave Assisted ◽  
Catalyst Free ◽  
Highly Efficient

A highly efficient unprecedented catalyst-free microwave-assisted procedure for synthesizing benzo[d]imidazo[2,1-b]thiazoles and N-alkylated 2-aminobenzo[d]oxazol in green media was developed.

A simple three-component condensation: Highly efficient microwave-assisted one-pot synthesis of polyfunctional pyridine derivatives

2009 ◽  
Vol 46 (1) ◽  
pp. 54-57 ◽  
Author(s):  
Shujiang Tu ◽  
Dianxiang Zhou ◽  
Longji Cao ◽  
Chunmei Li ◽  
Qingqing Shao
Keyword(s):  
Pyridine Derivatives ◽  
One Pot ◽  
Microwave Assisted ◽  
Highly Efficient ◽  
One Pot Synthesis

The highly efficient air oxidation of aryl and alkyl boronic acids by a microwave-assisted protocol under transition metal-free conditions

2019 ◽  
Vol 21 (17) ◽  
pp. 4614-4618 ◽  
Author(s):  
Weiyan Yin ◽  
Xizhi Pan ◽  
Wenxi Leng ◽  
Jian Chen ◽  
Haifeng He
Keyword(s):  
Transition Metal ◽  
Boronic Acids ◽  
Air Oxidation ◽  
Metal Free ◽  
Microwave Assisted ◽  
Highly Efficient

A rapid, green and efficient microwave-assisted protocol is developed for the air oxidation of boronic acids to phenols and alcohols under transition metal-free conditions.

Microwave-Assisted Synthesis of 2-(2-Nitroethenly)thiophene from 2-Thiophenecarboxaldehyde and Nitromethane

2012 ◽  
Vol 268-270 ◽  
pp. 500-503
Author(s):  
Jun De Xing ◽  
Zhi Liu ◽  
Zhao Yu Zhang ◽  
Xiao Fei Jia
Keyword(s):  
Energy Source ◽  
Reaction Time ◽  
Microwave Irradiation ◽  
Knoevenagel Condensation ◽  
Microwave Assisted Synthesis ◽  
Beta Alanine ◽  
Microwave Assisted ◽  
Reaction Condition ◽  
Efficient Access

2-(2-Nitroethenly)thiophene can be obtained from 2-thiophenecarboxaldehyde and nitromethane under Knoevenagel condensation conditions. We used beta-alanine as a catalyst and microwave irradiation as the energy source. Different reaction condition, such as beta-alanine consumption and reaction time were studied. The results indicate that the application of microwave irradiation increases the yield of desired compound. beta-Alanine-catalyzed activation of 2-thiophenecarboxaldehyde provides an efficient access to 2-(2-nitroethenly)thiophene with reusability of the catalyst.

scholarly journals Microwave-assisted one-pot synthesis in water of carbonylpyrazolo[3,4-b]pyridine derivatives catalyzed by InCl3 and sonochemical assisted condensation with aldehydes to obtain new chalcone derivatives containing the pyrazolopyridinic moiety

RSC Advances ◽  
2017 ◽  
Vol 7 (79) ◽  
pp. 50044-50055 ◽  
Author(s):  
Efrain Polo ◽  
Karoll Ferrer-Pertuz ◽  
Jorge Trilleras ◽  
Jairo Quiroga ◽  
Margarita Gutiérrez
Keyword(s):  
Microwave Irradiation ◽  
Aqueous Media ◽  
Pyridine Derivatives ◽  
One Pot ◽  
Chalcone Derivatives ◽  
Microwave Assisted ◽  
One Pot Synthesis ◽  
One Pot Condensation

Pyrazolo[3,4-b]pyridines derivatives have been synthesized via one-pot condensation of 3-methyl-1-phenyl-1H-pyrazolo-5-amine (1), paraformaldehyde (2) and β-diketones (3) under microwave irradiation in aqueous media catalyzed by InCl3.

Regioselective and Transition-Metal-Free Addition of tert-Butyl Magnesium Reagents to Pyridine Derivatives: A Convenient Method for the Synthesis of 3-Substituted 4-tert-Butylpyridine Derivatives

Synthesis ◽  
2017 ◽  
Vol 49 (17) ◽  
pp. 4055-4064 ◽  
Author(s):  
Sebastian Rappenglück ◽  
Karin Niessen ◽  
Thomas Seeger ◽  
Franz Worek ◽  
Horst Thiermann ◽  
...  
Keyword(s):  
Transition Metal ◽  
Convenient Method ◽  
Pyridine Derivatives ◽  
Reaction Sequence ◽  
Metal Free ◽  
Tert Butyl ◽  
Microwave Assisted ◽  
Butyl Group ◽  
Tert Butyl Group ◽  
Regioselective Addition

A variety of 3,4-disubstituted pyridine derivatives with a tert-butyl group in the 4-position were synthesized in a transition-metal-free, two-step reaction sequence from 3-substituted pyridine precursors. Highly regioselective addition of t-Bu2Mg to TIPS-activated pyridines and an efficient microwave-assisted aromatization with sulfur as oxidant afforded the desired 3,4-disubstituted pyridine derivatives in moderate to excellent yields. The method is compatible with many functional groups such as ester, amide, halide, nitrile or alkyne groups present in the 3-position.

Microwave-assisted synthesis of novel 2,3-disubstituted imidazo[1,2-a]pyridines via one-pot three component reactions

RSC Advances ◽  
2015 ◽  
Vol 5 (25) ◽  
pp. 19724-19733 ◽  
Author(s):  
Shaik Karamthulla ◽  
Md. Nasim Khan ◽  
Lokman H. Choudhury
Keyword(s):  
Microwave Irradiation ◽  
Molecular Iodine ◽  
Microwave Assisted Synthesis ◽  
One Pot ◽  
Metal Free ◽  
Microwave Assisted ◽  
Three Component Reaction

An expeditious one-pot, metal-free, three-component reaction of arylglyoxals, cyclic 1,3-dicarbonyls and 2-aminopyridines in the presence of molecular iodine under microwave irradiation is reported.

Convenient Synthesis of 2,4-Disubstituted Chromeno[4,3-b]Pyridine by Microwave Assisted One Pot Three Component Protocol

2020 ◽  
Vol 17 ◽  
Author(s):  
Ghanshyam Jadhav ◽  
Vijay Medhane ◽  
Dattatray Deshmukh
Keyword(s):  
Reaction Time ◽  
Microwave Irradiation ◽  
Aromatic Aldehydes ◽  
Pyridine Derivatives ◽  
Substituted Anilines ◽  
One Pot ◽  
Microwave Assisted ◽  
Synthetic Strategy ◽  
Convenient Synthesis ◽  
Scalable Synthesis

: We herein, describe efficient and scalable synthesis of 2,4-diaryl substituted chromene [43-b] pyridine derivatives using multicomponent reaction strategy by microwave irradiation of 4-amino 2-oxo-2H-chromene, aromatic aldehydes and substituted anilines. This synthetic strategy was found to be very useful as it follows environment benign protocol, also it gives good outcome in terms of yield and requires shorter reaction time.

scholarly journals Microwave-assisted green construction of imidazole-fused hybrid scaffolds using 2-aminobenzimidazoles as building blocks

RSC Advances ◽  
2021 ◽  
Vol 11 (35) ◽  
pp. 21367-21374
Author(s):  
Jung Pyo Kwak ◽  
Pham Duy Quang Dao ◽  
Nam Sik Yoon ◽  
Chan Sik Cho
Keyword(s):  
Transition Metal ◽  
Microwave Irradiation ◽  
Green Synthesis ◽  
Building Blocks ◽  
Metal Free ◽  
Microwave Assisted ◽  
Green Construction ◽  
Hybrid Scaffolds

A green synthesis of trinuclear imidazole-fused hybrid scaffolds has been developed by transition metal-free double C(sp2)–N coupling and cyclization of 2-(2-bromoaryl)- and 2-(2-bromovinyl)imidazoles with 2-aminobenzimidazoles as building blocks under microwave irradiation.

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