A novel indomethacin/methotrexate/MMP-9 siRNA in situ hydrogel with dual effects of anti-inflammatory activity and reversal of cartilage disruption for the synergistic treatment of rheumatoid arthritis

Nanoscale ◽  
2020 ◽  
Vol 12 (15) ◽  
pp. 8546-8562 ◽  
Author(s):  
Na Yin ◽  
Xinyi Tan ◽  
Hongbing Liu ◽  
Fengming He ◽  
Ning Ding ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Activity ◽  
In Situ Hydrogel ◽  
Anti Inflammatory

The D/siRNA-NGel was constructed to alleviate pain and swelling, delay the progression of RA, and reverse cartilage and bone disruption.

scholarly journals Activity of Tokulo (Kleinhovia hospita L.) as Anti Rheumatoid Arthritis and Anti-inflammatory in White Rats Induced by Complete Freud Adjuvant (CFA)

2021 ◽  
Vol 5 (3) ◽  
pp. 233-238
Author(s):  
Fatma Sari Siharis ◽  
Selpirahmawati Saranani ◽  
Nurlansi Nurlansi
Keyword(s):  
Rheumatoid Arthritis ◽  
Ethanol Extract ◽  
Inflammatory Activity ◽  
White Rats ◽  
Nsaid Group ◽  
Anti Inflammatory

Tokulo (Kleinhovia hospita) leaves are commonly used by Moronene people (Southeast Sulawesi) to treat headaches. This is supported scientifically from research which states that tokulo leaves have analgesic and anti-inflammatory activity. The NSAID group is included in the anti-rheumatoid arthritis therapy. To determine the anti-RA activity of this plant, a study was carried out on CFA-induced rats. Based on the results of the study, it is known that the ethanol extract of tokulo leaves has anti-RA and anti-inflammatory activity in CFA-induced rats. Keywords: Kleinhovia hospita, Rheumatoid Arthritis, Inflammation

scholarly journals Ibuprofen in rheumatoid arthritis. Clinical study of analgesic and anti-inflammatory activity.

1968 ◽  
Vol 27 (5) ◽  
pp. 457-462 ◽  
Author(s):  
M K Jasani ◽  
W W Downie ◽  
B M Samuels ◽  
W W Buchanan
Keyword(s):  
Rheumatoid Arthritis ◽  
Clinical Study ◽  
Inflammatory Activity ◽  
Anti Inflammatory

Solution equilibria and the X-ray structure of Cu(ii) complexation with 3-amino-N-(pyridin-2-ylmethyl)propanamide, a pseudo-mimic of human serum albumin

2016 ◽  
Vol 45 (42) ◽  
pp. 17010-17019 ◽  
Author(s):  
Graham E. Jackson ◽  
Fatin M. Elmagbari ◽  
Ahmed N. Hammouda ◽  
Raffaele P. Bonomo
Keyword(s):  
Rheumatoid Arthritis ◽  
Human Serum Albumin ◽  
Serum Albumin ◽  
Human Serum ◽  
Copper Complexes ◽  
Inflammatory Activity ◽  
X Ray ◽  
Solution Equilibria ◽  
Anti Inflammatory

Copper complexes have anti-inflammatory activity in the treatment of inflammation associated with rheumatoid arthritis (RA).

scholarly journals Naringin in Combination with Isothiocyanates as Liposomal Formulations Potentiates the Anti-inflammatory Activity in Different Acute and Chronic Animal Models of Rheumatoid Arthritis

ACS Omega ◽  
2020 ◽  
Vol 5 (43) ◽  
pp. 28319-28332
Author(s):  
Sangeeta Mohanty ◽  
Ashish Kumar Sahoo ◽  
V. Badireenath Konkimalla ◽  
Abhisek Pal ◽  
Sudam Chandra Si
Keyword(s):  
Rheumatoid Arthritis ◽  
Animal Models ◽  
Inflammatory Activity ◽  
Liposomal Formulations ◽  
Anti Inflammatory

In situ construction of hybrid MnO2@GO heterostructures for enhanced visible light photocatalytic, anti-inflammatory and anti-oxidant activity

2020 ◽  
Vol 44 (26) ◽  
pp. 11092-11104
Author(s):  
Jahangir Ahmad ◽  
Malik Wahid ◽  
Kowsar Majid
Keyword(s):  
Visible Light ◽  
Inflammatory Activity ◽  
Nano Composites ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Visible Light Photocatalytic

Hybrid MnO2@GO heterostructure nano-composites with enhanced visible light photocatalytic, anti-oxidant and anti-inflammatory activity.

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