scholarly journals Antibacterial activity of Mn(i) and Re(i) tricarbonyl complexes conjugated to a bile acid carrier molecule

Metallomics ◽  
2020 ◽  
Vol 12 (10) ◽  
pp. 1563-1575
Author(s):  
Jono W. Betts ◽  
Patrick Roth ◽  
Calum A. Pattrick ◽  
Hannah M. Southam ◽  
Roberto M. La Ragione ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bile Acid ◽  
Bacterial Infection ◽  
Carrier Molecule ◽  
Bile Acid Carrier

Mn and Re tricarbonyl bile acid conjugates exhibit low micromolar MIC values and rescue Galleria larvae from bacterial infection.

scholarly journals The bile acid deoxycholate elicits defences in Arabidopsis and reduces bacterial infection

2016 ◽  
Vol 18 (4) ◽  
pp. 540-554 ◽  
Author(s):  
Marco Zarattini ◽  
Alban Launay ◽  
Mahsa Farjad ◽  
Estelle Wénès ◽  
Ludivine Taconnat ◽  
...  
Keyword(s):  
Bile Acid ◽  
Bacterial Infection

scholarly journals Properties of the canalicular bile acid transport system in rat liver

1987 ◽  
Vol 242 (2) ◽  
pp. 465-469 ◽  
Author(s):  
P J Meier ◽  
A S Meier-Abt ◽  
J L Boyer
Keyword(s):  
Bile Acid ◽  
Substrate Specificity ◽  
Bile Acids ◽  
Rat Liver ◽  
Transport System ◽  
Acid Transport ◽  
Bile Acid Transport ◽  
Canalicular Bile ◽  
Disulphonic Acid ◽  
Bile Acid Carrier

4,4-Di-isothiocyanostilbene-2,2′-disulphonic acid inhibition of taurocholate efflux from canalicular vesicles was used to demonstrate that potential driven and ‘carrier’-mediated canalicular excretion of taurocholate occur via a common, rather than two separate, pathways. This electrogenic canalicular bile acid ‘carrier ’ preferentially transports trihydroxylated and conjugated dihydroxylated bile acids, but not the unphysiological oxo bile acids, and possibly extends its substrate specificity to other amphipathic molecules such as sulphobromophthalein.

Copper-doped mesoporous bioactive glass endows magnesium based scaffold with antibacterial activity and corrosion resistance

2021 ◽  
Author(s):  
Youwen Yang ◽  
changfu lu ◽  
mingli yang ◽  
dongsheng wang ◽  
Shuping Peng ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Corrosion Resistance ◽  
Bacterial Infection ◽  
Bioactive Glass ◽  
Bone Repair ◽  
Repair Material ◽  
Metal Element ◽  
Biodegradable Magnesium ◽  
Bone Repair Material ◽  
Mesoporous Bioactive Glass

Biodegradable magnesium (Mg) scaffold as bone repair material is desired to own antibacterial function to reduce the risk of bacterial infection. The alloying with antibacterial metal element such as copper...

Immunodetection of rainbow trout IL-8 cleaved-peptide: Tissue bioavailability and potential antibacterial activity in a bacterial infection context.

2021 ◽  
pp. 104182
Author(s):  
Daniel E. Sáenz-Martínez ◽  
Paula A. Santana ◽  
Mónica Aróstica ◽  
Juan C. Forero ◽  
Fanny Guzmán ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Rainbow Trout ◽  
Bacterial Infection

scholarly journals Ternary Ti alloys functionalised with antibacterial activity

2020 ◽  
Vol 10 (1) ◽  
Author(s):  
L. Bolzoni ◽  
M. Alqattan ◽  
L. Peters ◽  
Y. Alshammari ◽  
F. Yang
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Infection ◽  
Healing Process ◽  
Cost Effective ◽  
Negative Control ◽  
Systematic Analysis ◽  
Antibacterial Materials ◽  
Ti Alloys ◽  
The Cost ◽  
Powder Metallurgy Route

AbstractProsthesis bacterial infection occurring during surgery is a rising health issue. Pathogenic bacterial infection causes inflammation, interferes with the healing process, inhibits osteogenesis and, eventually, leads to implant failure. These issues can be tackled either by applying coatings or developing multifunctional (i.e. structural and antibacterial) materials. In this work, β eutectoid bearing functionalised Ti alloys were designed and manufactured via the cost-effective press and sinter powder metallurgy route. The systematic analysis of the ternary Ti–xCu–yMn alloys shows that the mechanical properties proportionally increase with the amount of alloying elements added. All the ternary Ti–xCu–yMn alloys have strong antibacterial activity against Escherichia coli with respect to the negative control (i.e. pure Ti). Our study demonstrates that ternary Ti–xCu–yMn alloys are promising candidates for structural prostheses functionalised with antibacterial capability.

A ruthenium nanoframe/enzyme composite system as a self-activating cascade agent for the treatment of bacterial infections

Nanoscale ◽  
2021 ◽  
Author(s):  
Yanan Liu ◽  
Dongliang Huo ◽  
Xufeng Zhu ◽  
Xu Chen ◽  
Ange Lin ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Bacterial Infection ◽  
Hydroxyl Radicals ◽  
Bacterial Infections ◽  
Composite System ◽  
Cascade Agent

The cascade catalytic strategy could effectively enhance the antibacterial activity by regulating the production of hydroxyl radicals (˙OH) in the sites of bacterial infection.

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