scholarly journals In situ vaccine application of inactivated CPMV nanoparticles for cancer immunotherapy

2021 ◽  
Author(s):  
Paul L. Chariou ◽  
Veronique Beiss ◽  
Yifeng Ma ◽  
Nicole F. Steinmetz
Keyword(s):  
Cancer Immunotherapy ◽  
Mosaic Virus ◽  
Biomedical Applications ◽  
Cowpea Mosaic Virus ◽  
Development Pipeline ◽  
In Situ Vaccine

Cowpea mosaic virus (CPMV) is currently in the development pipeline for multiple biomedical applications, including cancer immunotherapy.

scholarly journals Slow-Release Formulation of Cowpea Mosaic Virus for In Situ Vaccine Delivery to Treat Ovarian Cancer

2018 ◽  
Vol 5 (5) ◽  
pp. 1700991 ◽  
Author(s):  
Anna E. Czapar ◽  
Brylee David B. Tiu ◽  
Frank A. Veliz ◽  
Jonathan K. Pokorski ◽  
Nicole F. Steinmetz
Keyword(s):  
Ovarian Cancer ◽  
Mosaic Virus ◽  
Slow Release ◽  
Vaccine Delivery ◽  
Cowpea Mosaic Virus ◽  
Release Formulation ◽  
Slow Release Formulation ◽  
In Situ Vaccine

scholarly journals The unique potency of Cowpea mosaic virus (CPMV) in situ cancer vaccine

2020 ◽  
Vol 8 (19) ◽  
pp. 5489-5503
Author(s):  
Sourabh Shukla ◽  
Chao Wang ◽  
Veronique Beiss ◽  
Hui Cai ◽  
Torus Washington ◽  
...  
Keyword(s):  
Cancer Immunotherapy ◽  
Mosaic Virus ◽  
Cancer Vaccine ◽  
Cowpea Mosaic Virus ◽  
Icosahedral Viruses ◽  
Viral Nanoparticle

Plant viral nanoparticle CPMV outperforms other icosahedral viruses as an in situ vaccine for cancer immunotherapy.

scholarly journals In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer

2015 ◽  
Vol 11 (3) ◽  
pp. 295-303 ◽  
Author(s):  
P. H. Lizotte ◽  
A. M. Wen ◽  
M. R. Sheen ◽  
J. Fields ◽  
P. Rojanasopondist ◽  
...  
Keyword(s):  
Mosaic Virus ◽  
Metastatic Cancer ◽  
Cowpea Mosaic Virus

scholarly journals IMMU-73. GLIOMA IN SITU VACCINATION WITH COWPEA MOSAIC VIRUS NANOPARTICLES

2018 ◽  
Vol 20 (suppl_6) ◽  
pp. vi138-vi138
Author(s):  
Amber Kerstetter-Fogle ◽  
Sourabh Shukla ◽  
Veronique Beiss ◽  
Peggy Harris ◽  
Andrew Sloan ◽  
...  
Keyword(s):  
Mosaic Virus ◽  
Cowpea Mosaic Virus

scholarly journals Radiation Therapy Combined with Cowpea Mosaic Virus Nanoparticle in Situ Vaccination Initiates Immune-Mediated Tumor Regression

ACS Omega ◽  
2018 ◽  
Vol 3 (4) ◽  
pp. 3702-3707 ◽  
Author(s):  
Ravi Patel ◽  
Anna E. Czapar ◽  
Steven Fiering ◽  
Nancy L. Oleinick ◽  
Nicole F. Steinmetz
Keyword(s):  
Radiation Therapy ◽  
Mosaic Virus ◽  
Tumor Regression ◽  
Cowpea Mosaic Virus ◽  
Immune Mediated

Anodic synthesis of TiO2 nanotubes by step-up voltages

2021 ◽  
pp. 002199832110237
Author(s):  
V Sivaprakash ◽  
R Narayanan
Keyword(s):  
Corrosion Resistance ◽  
Tio2 Nanotubes ◽  
Biomedical Applications ◽  
Phase Changes ◽  
Electrochemical Anodization ◽  
Corrosion Resistant ◽  
Anodization Process ◽  
Anodic Synthesis ◽  
Input Potential

Fabrication of TiO2 nanotubes (NTs) has extensive application properties due to their high corrosion resistant and compatibility with biomedical applications, the synthesis of TiO2 nanotubes over titanium has drawn interest in various fields. The synthesis of TiO2 NTs using novel in-situ step-up voltage conditions in the electrochemical anodization process is recorded in this work. For manufacturing the NTs at 1 hour of anodization, the input potential of 30, 40 and 50 V was selected. With increasing step-up voltage during the anodization process, an improvement in the NTs was observed, favoring corrosion resistance properties. The surface of NTs enhances the structure of the ribs, raising the potential for feedback over time. XRD was used to analyze phase changes, and HR-SEM analyzed surface topography. Impedance tests found that longer NTs improved the corrosion resistance.

scholarly journals Capsid Proteins of Cowpea Mosaic Virus Transiently Expressed in Protoplasts Form Virus-like Particles

Virology ◽  
1996 ◽  
Vol 224 (1) ◽  
pp. 352-355 ◽  
Author(s):  
Joan Wellink ◽  
Jan Verver ◽  
Jan Van Lent ◽  
A.Van Kammen
Keyword(s):  
Mosaic Virus ◽  
Capsid Proteins ◽  
Cowpea Mosaic Virus ◽  
Virus Like Particles

Tumor Microenvironment-Triggered In-Situ Cancer Vaccines with Dual Immunogenic Cell Death Inductions for Elevated Antitumor and Antimetastatic Therapy

Nanoscale ◽  
2021 ◽  
Author(s):  
Jun Lin ◽  
Binbin Ding ◽  
Pan Zheng ◽  
Dong Li ◽  
Meifang Wang ◽  
...  
Keyword(s):  
Cell Death ◽  
Tumor Microenvironment ◽  
Immune Responses ◽  
Cancer Immunotherapy ◽  
Cancer Vaccines ◽  
High Specificity ◽  
The Body ◽  
Immunogenic Cell Death ◽  
Specific Antigens

Cancer vaccine is to make tumor-specific antigens into vaccines, which then are injected back into the body to activate immune responses for cancer immunotherapy. Despite the high specificity and therapeutic...

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