scholarly journals A microfluidic device for TEM sample preparation

Lab on a Chip ◽  
2020 ◽  
Vol 20 (22) ◽  
pp. 4186-4193
Author(s):  
Janosch Hauser ◽  
Gustaf Kylberg ◽  
Mathieu Colomb-Delsuc ◽  
Göran Stemme ◽  
Ida-Maria Sintorn ◽  
...  

We present a capillary-driven microfluidic single-use device that prepares a TEM grid with minimal user interaction. The user only initiates the sample preparation process, waits for about one minute and then collects the TEM grid, ready for imaging.

Author(s):  
Ng Sea Chooi ◽  
Chor Theam Hock ◽  
Ma Choo Thye ◽  
Khoo Poh Tshin ◽  
Dan Bockelman

Abstract Trends in the packaging of semiconductors are towards miniaturization and high functionality. The package-on-package(PoP) with increasing demands is beneficial in cost and space saving. The main failure mechanisms associated with PoP technology, including open joints and warpage, have created a lot of challenges for Assembly and Failure Analysis (FA). This paper outlines the sample preparation process steps to overcome the challenges to enable successful failure analysis and optical probing.


2002 ◽  
Vol 975 (1) ◽  
pp. 105-112 ◽  
Author(s):  
Yoshihiro Saito ◽  
Masatoshi Nojiri ◽  
Motohiro Imaizumi ◽  
Yuji Nakao ◽  
Yoriko Morishima ◽  
...  

2010 ◽  
Vol 4 (4) ◽  
pp. 329-337
Author(s):  
Fabio Pereira ◽  
◽  
Fabiana Vieira ◽  
Luiz de Castro ◽  
Ricardo Michel ◽  
...  

In this work the influence of different configurations in the sample preparation process on commercial polyacrylonitrile-based carbon fibers mechanical tests were studied. Mechanical properties, such as tensile strength, Young’s modulus, elongation and Weibull modulus, were evaluated. The results showed that all sample preparation steps may have strong influence on the results.


Lab on a Chip ◽  
2015 ◽  
Vol 15 (6) ◽  
pp. 1533-1544 ◽  
Author(s):  
John Nguyen ◽  
Yuan Wei ◽  
Yi Zheng ◽  
Chen Wang ◽  
Yu Sun

We present a monolithic microfluidic device capable of on-chip sample preparation for both RBC and WBC measurements from whole blood.


2019 ◽  
Vol 11 (5) ◽  
pp. 559-565 ◽  
Author(s):  
Christopher R. Phaneuf ◽  
Kyle J. Seamon ◽  
Tyler P. Eckles ◽  
Anchal Sinha ◽  
Joseph S. Schoeniger ◽  
...  

Combined activity- and immunoassays for CRISPR/Cas9 on a portable microfluidic device with integrated sample preparation from clinical sample matrices.


Paliva ◽  
2021 ◽  
pp. 141-148
Author(s):  
Hana Lisá ◽  
Martin Lisý ◽  
Patrik Elbl ◽  
Marek Baláš ◽  
Tereza Zlevorová ◽  
...  

The characteristic properties of non-wood biomass used in combustion processes are monitored, such as water content, ash, volatile matter. Biomass is usually not homogenous and of suitable dimensions for these determinations. This is the reason for the necessary adjustment of samples for analysis. But modifying the samples may change their properties. In this publication, the influence of the grinding process in a rotor mill on the content of water, volatile matter and ash in non-wood biomass samples was studied. Samples of flax, Crambe abyssinica, amaranth and rye were analyzed. All analyses showed moisture loss from the sample during grinding and in the case of flax, the loss of volatile matter was observed. It means the rotor mill is suitable for sample preparation prior to analysis. But for oil plants it is necessary to choose another mill or adjustment method.


Author(s):  
K.J. Ostreicher ◽  
C.M. Sung

Since the discovery of the Lucalox process, a considerable amount of research effort has been devoted to locating both impurities and additives in transparent polycrystalline alumina (PCA). The control of grain growth and porosity by introducing dopants such as MgO and Y2O3 has been shown to directly affect the strength and transmittance properties of the material. The presence of impurities or dopants in excess of their solubility limits leads to precipitation in the bulk and along grain boundaries. It is essential that TEM sample preparation be controlled so as not to introduce damage or pull-out of sec materials it becomes a good method to obtain information concerning grain size and shape, grain orientation relationships, and porosity. The purpose of this study is to describe such a sample preparation process and demonstrate its usefulness in allowing effective correlation of optical microscopy and TEM results.


Author(s):  
Tomáš Hrnčíř ◽  
Marek Šikula ◽  
Pavel Doleže ◽  
Claudio A. G. Savoia

Abstract Multipurpose sample holder for advanced Transmission Electron Microscopy (TEM) sample preparation which reduces cost of the tool and most importantly simplifies the workflow is introduced. Following the current demand for user-friendly interface, semi-automated approach is aimed to be build up. Abilities to prepare advanced TEM lamellae in various geometries without rotary nanomanipulator and using various end-point detection signals are perceived as biggest advantages of this design.


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