An entirely solvent-free photooxygenation of olefins under continuous flow conditions

2020 ◽  
Vol 22 (8) ◽  
pp. 2359-2364 ◽  
Author(s):  
Patrick Bayer ◽  
Axel Jacobi von Wangelin
Keyword(s):  
Singlet Oxygen ◽  
Continuous Flow ◽  
Flow Reactor ◽  
Space Time ◽  
Solvent Free ◽  
Flow Conditions ◽  
High Substrate ◽  
Solvent Free Conditions ◽  
High Space ◽  
Very High

Photooxygenations of alkenes with singlet oxygen have been performed under solvent-free conditions in a flow reactor under VIS irradiation. The reaction operates at very high substrate/sensitizer ratios and enables high space–time yields.

Metal- and solvent-free synthesis of aminoalcohols under continuous flow conditions

2020 ◽  
Vol 5 (2) ◽  
pp. 289-299 ◽  
Author(s):  
Abdo-Alslam Alwakwak ◽  
Yingxin He ◽  
Ahmed Almuslem ◽  
Matthew Senter ◽  
Arun K. Itta ◽  
...  
Keyword(s):  
Chemical Transformation ◽  
Hollow Fiber ◽  
Continuous Flow ◽  
Heterogeneous Catalysts ◽  
Flow Reactor ◽  
Solvent Free ◽  
Flow Conditions ◽  
Continuous Flow Reactor ◽  
Solvent Free Synthesis

Multifunctional organocatalysts were immobilized on porous hollow fiber polymer and used as intelligent and cooperative heterogeneous catalysts and continuous flow reactor for sustainable chemical transformation.

Generalized high-temperature synthesis of zeolite catalysts with unpredictably high space-time yields (STYs)

2017 ◽  
Vol 5 (6) ◽  
pp. 2613-2618 ◽  
Author(s):  
Chaoqun Bian ◽  
Changsheng Zhang ◽  
Shuxiang Pan ◽  
Fang Chen ◽  
Weiping Zhang ◽  
...  
Keyword(s):  
High Temperature ◽  
Space Time ◽  
Solvent Free ◽  
Zeolite Catalysts ◽  
High Quality ◽  
Temperature Synthesis ◽  
High Temperature Synthesis ◽  
Solvent Free Conditions ◽  
High Space

High quality zeolite catalysts are efficiently synthesized by fast crystallization at higher temperatures under solvent-free conditions.

scholarly journals Polyionic polymers – heterogeneous media for metal nanoparticles as catalyst in Suzuki–Miyaura and Heck–Mizoroki reactions under flow conditions

2009 ◽  
Vol 5 ◽  
Author(s):  
Klaas Mennecke ◽  
Andreas Kirschning
Keyword(s):  
Metal Nanoparticles ◽  
Continuous Flow ◽  
Heterogeneous Media ◽  
Flow Reactor ◽  
Functionalized Polymers ◽  
Flow Conditions

The preparation of monolithic polyionic supports which serve as efficient heterogeneous supports for palladium(0) nanoparticles is described. These functionalized polymers were incorporated inside a flow reactor and employed in Suzuki–Miyaura and Heck cross couplings under continuous flow conditions.

Robust Organic Photosensitizers Immobilized on a Vinylimidazolium Functionalized Support for Singlet Oxygen Generation under Continuous-Flow Conditions

Synlett ◽  
2020 ◽  
Vol 31 (05) ◽  
pp. 497-501 ◽  
Author(s):  
Koichiro Masuda ◽  
Yao Wang ◽  
Shun-ya Onozawa ◽  
Shigeru Shimada ◽  
Nagatoshi Koumura ◽  
...  
Keyword(s):  
Singlet Oxygen ◽  
Rose Bengal ◽  
Crucial Role ◽  
Continuous Flow ◽  
Organic Molecules ◽  
Continuous Operation ◽  
Flow Conditions ◽  
Oxygen Generation ◽  
Singlet Oxygen Generation ◽  
Flow Reaction

Rose Bengal was immobilized on a vinylimidazolium functionalized support, and the heterogeneous organic photosensitizer thus prepared was applied for photooxidation reactions of organic molecules under continuous-flow conditions. Substituents of the cation part of the support were found to play a crucial role in determining the lifetime of the catalyst. More than 11 days continuous operation of a flow reaction was achieved.

Solvent-free organocatalytic preparation of cyclic organic carbonates under scalable continuous flow conditions

2019 ◽  
Vol 4 (1) ◽  
pp. 17-26 ◽  
Author(s):  
Zhiguo Wang ◽  
Romaric Gérardy ◽  
Guillaume Gauron ◽  
Christian Damblon ◽  
Jean-Christophe M. Monbaliu
Keyword(s):  
Continuous Flow ◽  
Dimethyl Carbonate ◽  
Solvent Free ◽  
Flow Conditions ◽  
Organic Carbonates

A solvent-free organocatalyzed process for the transesterification of dimethyl carbonate (DMC) with 1,2-diols under scalable continuous flow conditions.

Morpholinium hydrogen sulfate (MHS) ionic liquid as an efficient catalyst for the synthesis of bio-active multi-substituted imidazoles (MSI) under solvent-free conditions

2017 ◽  
Vol 72 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Adel A. Marzouk ◽  
Antar A. Abdelhamid ◽  
Shaaban K. Mohamed ◽  
Jim Simpson
Keyword(s):  
Ionic Liquid ◽  
Reaction Times ◽  
Aromatic Aldehydes ◽  
Solvent Free ◽  
Biologically Active ◽  
High Yield ◽  
Hydrogen Sulfate ◽  
Efficient Catalyst ◽  
Solvent Free Conditions ◽  
Very High

AbstractMorpholinium hydrogen sulfate as an ionic liquid was employed as a catalyst for the synthesis of a biologically active series of multi-substituted imidazoles by a four-component reaction involving the combination of benzil with different aromatic aldehydes, ammonium acetate, and 1-amino-2-propanol under solvent-free conditions. The key advantages of this method are shorter reaction times, very high yield, and ease of processing. Furthermore, the resulting products can be purified by a non-chromatographic method and the ionic liquid catalyst is reusable. All of these novel compounds have been fully characterized from spectral data. The X-ray crystal structures of two representative molecules are also detailed.

scholarly journals Development of an Efficient and Sustainable Synthesis of 2-(3-Methyl-1H-1,2,4-Triazol-1-Yl) Acetic Acid Under Continuous-Flow Conditions

2020 ◽  
Author(s):  
Simone Tortoioli ◽  
Astrid Friedli ◽  
Alice Prud’homme ◽  
Sylvia Richard-Bildstein ◽  
Philipp Kohler ◽  
...  
Keyword(s):  
Acetic Acid ◽  
Continuous Flow ◽  
Flow Reactor ◽  
Environmentally Benign ◽  
Sustainable Construction ◽  
Flow Conditions ◽  
Step Method ◽  
Metal Free ◽  
Free Process ◽  
Synthetic Routes

A novel, metal-free process for the challenging synthesis of 2-(3-methyl-1<i>H</i>-1,2,4-triazol-1-yl) acetic acid (<b>1</b>) is reported, which features an efficient condensation for the triazole build-up under flow conditions. This continuous, two-step method is atom economical, highly selective and environmentally benign, due to the avoidance of chromatography and isolation steps. Compared to the earlier batch synthetic routes, higher yields were achieved in a flow reactor. In addition, a highly energetic intermediate could be controlled and handled in a safe manner. To generalize the established route, several triazoles were finally prepared under the described conditions, confirming that the methodology could find useful applications for the rapid and sustainable construction of differentially functionalized 1,2,4-triazoles.

scholarly journals Safe generation and use of bromine azide under continuous flow conditions – selective 1,2-bromoazidation of olefins

2016 ◽  
Vol 14 (3) ◽  
pp. 853-857 ◽  
Author(s):  
David Cantillo ◽  
Bernhard Gutmann ◽  
C. Oliver Kappe
Keyword(s):  
Continuous Flow ◽  
Flow Reactor ◽  
Flow Conditions ◽  
Continuous Flow Reactor

Hazardous bromine azide (BrN3) can be safely generated and reacted with olefins in a continuous flow reactor under irradiation with light.

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