Soy protein and chitin sponge-like scaffolds: from natural by-products to cell delivery systems for biomedical applications

2020 ◽  
Vol 22 (11) ◽  
pp. 3445-3460 ◽  
Author(s):  
Kevin Las Heras ◽  
Edorta Santos-Vizcaino ◽  
Tania Garrido ◽  
Francisco Borja Gutierrez ◽  
Jose Javier Aguirre ◽  
...  
Keyword(s):  
Soy Protein ◽  
Renewable Resources ◽  
Biomedical Applications ◽  
Delivery Systems ◽  
Cell Delivery ◽  
Plant Proteins ◽  
By Products

Natural and renewable resources, such as plant proteins and marine polysaccharides, to manufacture scaffolds with suitable properties for biomedical applications.

Rediscovering Tocophersolan: a renaissance for nano-based drug delivery and nanotheranostic applications

2020 ◽  
Vol 21 ◽  
Author(s):  
Dickson Pius Wande ◽  
Qin Cui ◽  
Shijie Chen ◽  
Cheng Xu ◽  
Hui Xiong ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Drug Dissolution ◽  
Glycol Succinate ◽  
Permeation Enhancer ◽  
P Glycoprotein ◽  
Us Fda ◽  
Anticancer Compound

: As a unique and pleiotropic polymer, d-alpha-tocopheryl polyethylene glycol succinate (Tocophersolan) is a polymeric synthetic version of vitamin E. Tocophersolan has attracted enormous attention as a versatile excipient in different biomedical applications including drug delivery systems and nutraceuticals. The multiple inherent properties of Tocophersolan make it play flexible roles in drug delivery system design, including excipients with outstanding biocompatibility, solubilizer with the ability of promoting drug dissolution, drug permeation enhancer, P-glycoprotein inhibitor and anticancer compound. For these reasons, Tocophersolan has been widely used for improving the bioavailability of numerous pharmaceutical active ingredients. Tocophersolan has been approved by stringent regulatory authorities (such as US FDA, EMA, and PMDA) as a safe pharmaceutical excipient. In this review, we systematically curated current advances in nano-based delivery systems consisting of Tocophersolan with possibilities for futuristic applications in drug delivery, gene therapy, and nanotheranostic.

scholarly journals Aloe Vera-Mediated Te Nanostructures: Highly Potent Antibacterial Agents and Moderated Anticancer Effects

Nanomaterials ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 514
Author(s):  
David Medina-Cruz ◽  
Ada Vernet-Crua ◽  
Ebrahim Mostafavi ◽  
María Ujué González ◽  
Lidia Martínez ◽  
...  
Keyword(s):  
Biomedical Applications ◽  
Aqueous Media ◽  
Aloe Vera ◽  
Multidrug Resistant ◽  
Dermal Fibroblasts ◽  
Anticancer Properties ◽  
Green Approach ◽  
Anticancer Effects ◽  
Synthesis Of Nanomaterials ◽  
By Products

Cancer and antimicrobial resistance to antibiotics are two of the most worrying healthcare concerns that humanity is facing nowadays. Some of the most promising solutions for these healthcare problems may come from nanomedicine. While the traditional synthesis of nanomaterials is often accompanied by drawbacks such as high cost or the production of toxic by-products, green nanotechnology has been presented as a suitable solution to overcome such challenges. In this work, an approach for the synthesis of tellurium (Te) nanostructures in aqueous media has been developed using aloe vera (AV) extracts as a unique reducing and capping agent. Te-based nanoparticles (AV-TeNPs), with sizes between 20 and 60 nm, were characterized in terms of physicochemical properties and tested for potential biomedical applications. A significant decay in bacterial growth after 24 h was achieved for both Methicillin-resistant Staphylococcus aureus and multidrug-resistant Escherichia coli at a relative low concentration of 5 µg/mL, while there was no cytotoxicity towards human dermal fibroblasts after 3 days of treatment. AV-TeNPs also showed anticancer properties up to 72 h within a range of concentrations between 5 and 100 µg/mL. Consequently, here, we present a novel and green approach to produce Te-based nanostructures with potential biomedical applications, especially for antibacterial and anticancer applications.

Lanthanide-doped upconversion nanoparticles complexed with nano-oxide graphene used for upconversion fluorescence imaging and photothermal therapy

2018 ◽  
Vol 6 (4) ◽  
pp. 877-884 ◽  
Author(s):  
Po Li ◽  
Yue Yan ◽  
Binlong Chen ◽  
Pan Zhang ◽  
Siling Wang ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Fluorescence Imaging ◽  
Photothermal Therapy ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Research Interest ◽  
Upconversion Nanoparticles ◽  
Multifunctional Nanoparticles ◽  
Nano Oxide

In recent years, multifunctional nanoparticles have attracted much research interest in various biomedical applications such as biosensors, diagnosis, and drug delivery systems.

Natural Polymers for Biodegradable Dressings to Save the Environment

2021 ◽  
Vol 6 (2) ◽  
Keyword(s):  
Greenhouse Gas Emissions ◽  
Greenhouse Gas ◽  
Renewable Resources ◽  
Raw Materials ◽  
Current System ◽  
Future Generations ◽  
Natural Polymers ◽  
Surgical Masks ◽  
By Products ◽  
Global Water

The current fashion system uses high volumes of non-renewable resources to produce clothes, being responsible for 10% of the global greenhouse gas emissions into the atmosphere every year and 20%of the global water wasted. At the same time people are buying 60%more clothing than 15 Years ago, which going in the landfills, causes 92 million tons of waste each year. This waste has been further increased by the surgical masks used for COVID-19 pandemic. Thus, a new way of designing and producing clothing needs to be incorporated into the current system to facilitate its recycling making it more circular. New tissues, therefore, are proposed made by natural polysaccharides, embedded by micro- Nano capsules of chitin Nano fibrils and Nano lignin all obtained as by- products from food and forestry waste respectively. Thus, pollution and waste will be reduced and the natural raw materials will be maintained for the future generations.

scholarly journals Bioceramics: from bone substitutes to nanoparticles for drug delivery

2019 ◽  
Vol 91 (4) ◽  
pp. 687-706 ◽  
Author(s):  
María Vallet-Regí
Keyword(s):  
Drug Delivery ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Bone Repair ◽  
Research Team ◽  
Research Work ◽  
Bone Substitutes ◽  
Delivery Systems ◽  
Smart Drug ◽  
Smart Drug Delivery

Abstract Since the second half of the 20th century, bioceramics are used for bone repair and regeneration. Inspired by bones and teeth, and aimed at mimicking their structure and composition, several artificial bioceramics were developed for biomedical applications. And nowadays, in the 21st century, with the increasing prominence of nanoscience and nanotechnology, certain bioceramics are being used to build smart drug delivery systems, among other applications. This minireview will mainly describe both tendencies through the research work carried out by the research team of María Vallet-Regí.

Varietal differences of carbohydrates in defatted soybean flour and soy protein isolate by-products

2008 ◽  
Vol 72 (4) ◽  
pp. 664-672 ◽  
Author(s):  
E.M. Bainy ◽  
S.M. Tosh ◽  
M. Corredig ◽  
V. Poysa ◽  
L. Woodrow
Keyword(s):  
Soy Protein ◽  
Soy Protein Isolate ◽  
Protein Isolate ◽  
Soybean Flour ◽  
Varietal Differences ◽  
By Products ◽  
Defatted Soybean Flour

Barium alginate cell-delivery systems: correlation between technological parameters

2002 ◽  
Vol 242 (1-2) ◽  
pp. 389-391 ◽  
Author(s):  
M.L Torre ◽  
M Faustini ◽  
R Norberti ◽  
L Maggi ◽  
G Maffeo ◽  
...  
Keyword(s):  
Delivery Systems ◽  
Cell Delivery ◽  
Technological Parameters
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