Can cheese mites, maggots and molds enhance bioactivity? Peptidomic investigation of functional peptides in four traditional cheeses

2021 ◽  
Author(s):  
Randall C. Robinson ◽  
Søren D. Nielsen ◽  
David C. Dallas ◽  
Daniela Barile
Keyword(s):  
Traditional Cheeses ◽  
Functional Peptides ◽  
Orbitrap Ms

Peptide sequences identified in four cheeses by LC-Orbitrap MS/MS.

scholarly journals 3PC-065 Impact of light stress on the isoform profile of nivolumab (Opdivo) in opened vials estimated by (RP)UHPLC-UV-(HESI/Orbitrap)-MS

2021 ◽  
Author(s):  
A Torrente-López ◽  
J Hermosilla-Fernández ◽  
J Hernández-Jiménez ◽  
J Cabeza ◽  
A Salmerón-García ◽  
...  
Keyword(s):  
Light Stress ◽  
Orbitrap Ms

Recent Progress in Functional Peptides Designed for Tumor-targeted Imaging and Therapy

2021 ◽  
Author(s):  
Xingyu Wang ◽  
Yi-Hui Wang ◽  
Zhen Song ◽  
Xin-Yuan Hu ◽  
Jiping Wei ◽  
...  
Keyword(s):  
Recent Progress ◽  
Targeted Imaging ◽  
Medical Field ◽  
Diagnosis And Therapy ◽  
Low Toxicity ◽  
Functional Peptides ◽  
Living Organisms

The diagnosis and therapy of tumors are challenging problems in the medical field. Peptides are derived from living organisms with excellent biocompatibility, low-toxicity/non-toxicity, and negligible immunogenicity, and they have been...

Novel Bacillus Milk-Clotting Enzyme Produces Diverse Functional Peptides in Semihard Cheese

2021 ◽  
Vol 69 (9) ◽  
pp. 2784-2792
Author(s):  
Fanqiang Meng ◽  
Haizhen Zhao ◽  
Fengxia Lu ◽  
Xiaomei Bie ◽  
Zhaoxin Lu ◽  
...  
Keyword(s):  
Milk Clotting ◽  
Milk Clotting Enzyme ◽  
Functional Peptides

The analysis of active compounds in Flos Chrysanthemi Indici by UHPLC Q exactive HF hybrid Quadrupole-Orbitrap MS and comprehensive quality assessment of its preparation

2021 ◽  
Author(s):  
Tingting Dai ◽  
Guoxiang Sun
Keyword(s):  
Antioxidant Activity ◽  
Correlation Analysis ◽  
Quality Assessment ◽  
Active Compounds ◽  
Q Exactive ◽  
Orbitrap Ms

Active compounds’ analysis between Flos Chrysanthemi Indici (FCI) and its preparation (FCIP), and the comprehensive quality assessment of its preparation as well as the correlation analysis between the antioxidant activity and fingerprint.

scholarly journals High-Throughput Identification of Organic Compounds from Polygoni Multiflori Radix Praeparata (Zhiheshouwu) by UHPLC-Q-Exactive Orbitrap-MS

Molecules ◽  
2021 ◽  
Vol 26 (13) ◽  
pp. 3977
Author(s):  
Shaoyun Wang ◽  
Xiaozhu Sun ◽  
Shuo An ◽  
Fang Sang ◽  
Yunli Zhao ◽  
...  
Keyword(s):  
High Performance ◽  
Chemical Constituents ◽  
Water Extract ◽  
Ethanol Extract ◽  
In Vivo Studies ◽  
Polygonum Multiflorum ◽  
Q Exactive ◽  
Orbitrap Ms

Polygoni Multiflori Radix Praeparata (PMRP), as the processed product of tuberous roots of Polygonum multiflorum Thunb., is one of the most famous traditional Chinese medicines, with a long history. However, in recent years, liver adverse reactions linked to PMRP have been frequently reported. Our work attempted to investigate the chemical constituents of PMRP for clinical research and safe medication. In this study, an effective and rapid method was established to separate and characterize the constituents in PMRP by combining ultra-high performance liquid chromatography with hybrid quadrupole-orbitrap mass spectrometry (UHPLC-Q-Exactive Orbitrap-MS). Based on the accurate mass measurements for molecular and characteristic fragment ions, a total of 103 compounds, including 24 anthraquinones, 21 stilbenes, 15 phenolic acids, 14 flavones, and 29 other compounds were identified or tentatively characterized. Forty-eight compounds were tentatively characterized from PMRP for the first time, and their fragmentation behaviors were summarized. There were 101 components in PMRP ethanol extract (PMRPE) and 91 components in PMRP water extract (PMRPW). Simultaneously, the peak areas of several potential xenobiotic components were compared in the detection, which showed that PMRPE has a higher content of anthraquinones and stilbenes. The obtained results can be used in pharmacological and toxicological research and provided useful information for further in vitro and in vivo studies.

scholarly journals Identification of Components in Citri Sarcodactylis Fructus from Different Origins via UPLC-Q-Exactive Orbitrap/MS

ACS Omega ◽  
2021 ◽  
Author(s):  
Kanghui Wang ◽  
Jingyuan Tian ◽  
Yueshan Li ◽  
Mengshi Liu ◽  
Yingxin Chao ◽  
...  
Keyword(s):  
Q Exactive ◽  
Different Origins ◽  
Orbitrap Ms
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