scholarly journals Proline isomerization effects in the amyloidogenic protein β2-microglobulin

2021 ◽  
Vol 23 (1) ◽  
pp. 356-367
Author(s):  
Maria Celeste Maschio ◽  
Jacopo Fregoni ◽  
Carla Molteni ◽  
Stefano Corni
Keyword(s):  
Amyloid Fibrils ◽  
Structural Modifications ◽  
Proline Isomerization ◽  
Β2 Microglobulin ◽  
Amyloidogenic Protein ◽  
Triggering Factor

The protein β2-microglobulin can aggregate in insoluble amyloid fibrils. By relying on extensive sampling simulations, we study the Pro32 isomerization as a possible triggering factor leading to structural modifications in β2-m.

scholarly journals Investigation into the Role of Macrophages in the Formation and Degradation of β2-Microglobulin Amyloid Fibrils

2007 ◽  
Vol 282 (40) ◽  
pp. 29691-29700 ◽  
Author(s):  
Isobel J. Morten ◽  
Walraj S. Gosal ◽  
Sheena E. Radford ◽  
Eric W. Hewitt
Keyword(s):  
Amyloid Fibrils ◽  
Β2 Microglobulin

Detection of two partially structured species in the folding process of the amyloidogenic protein β2-microglobulin

2001 ◽  
Vol 307 (1) ◽  
pp. 379-391 ◽  
Author(s):  
Fabrizio Chiti ◽  
Palma Mangione ◽  
Alessia Andreola ◽  
Sofia Giorgetti ◽  
Massimo Stefani ◽  
...  
Keyword(s):  
Folding Process ◽  
Β2 Microglobulin ◽  
Amyloidogenic Protein

scholarly journals Advanced Glycation End Product-Modified β2-Microglobulin is a Component of Amyloid Fibrils of Primary Localized Cutaneous Nodular Amyloidosis

2002 ◽  
Vol 118 (3) ◽  
pp. 479-484 ◽  
Author(s):  
Norihiro Fujimoto ◽  
Mayumi Yajima ◽  
Yoshihiro Ohnishi ◽  
Shingo Tajima ◽  
Akira Ishibashi ◽  
...  
Keyword(s):  
Amyloid Fibrils ◽  
Advanced Glycation ◽  
Advanced Glycation End Product ◽  
Β2 Microglobulin

Thermal Response with Exothermic Effects of β2-Microglobulin Amyloid Fibrils and Fibrillation

2009 ◽  
Vol 389 (3) ◽  
pp. 584-594 ◽  
Author(s):  
Kenji Sasahara ◽  
Hisashi Yagi ◽  
Hironobu Naiki ◽  
Yuji Goto
Keyword(s):  
Amyloid Fibrils ◽  
Thermal Response ◽  
Β2 Microglobulin

Heat-Triggered Conversion of Protofibrils into Mature Amyloid Fibrils of β2-Microglobulin†

Biochemistry ◽  
2007 ◽  
Vol 46 (11) ◽  
pp. 3286-3293 ◽  
Author(s):  
Kenji Sasahara ◽  
Hisashi Yagi ◽  
Hironobu Naiki ◽  
Yuji Goto
Keyword(s):  
Amyloid Fibrils ◽  
Β2 Microglobulin

Kinetic analysis of the polymerization and depolymerization of β2-microglobulin-related amyloid fibrils in vitro

2005 ◽  
Vol 1753 (1) ◽  
pp. 34-43 ◽  
Author(s):  
Suguru Yamamoto ◽  
Kazuhiro Hasegawa ◽  
Itaru Yamaguchi ◽  
Yuji Goto ◽  
Fumitake Gejyo ◽  
...  
Keyword(s):  
Kinetic Analysis ◽  
Amyloid Fibrils ◽  
Β2 Microglobulin

scholarly journals Conformation of Amyloid Fibrils of β2-Microglobulin Probed by Tryptophan Mutagenesis

2006 ◽  
Vol 281 (41) ◽  
pp. 31061-31069 ◽  
Author(s):  
Miho Kihara ◽  
Eri Chatani ◽  
Kentaro Iwata ◽  
Kaori Yamamoto ◽  
Takanori Matsuura ◽  
...  
Keyword(s):  
Amyloid Fibrils ◽  
Β2 Microglobulin

Kinetically Controlled Thermal Response of β2-Microglobulin Amyloid Fibrils

2005 ◽  
Vol 352 (3) ◽  
pp. 700-711 ◽  
Author(s):  
Kenji Sasahara ◽  
Hironobu Naiki ◽  
Yuji Goto
Keyword(s):  
Amyloid Fibrils ◽  
Thermal Response ◽  
Β2 Microglobulin ◽  
Kinetically Controlled

Proteomics of β2-microglobulin amyloid fibrils

2005 ◽  
Vol 1753 (1) ◽  
pp. 23-33 ◽  
Author(s):  
Monica Stoppini ◽  
Palma Mangione ◽  
Maria Monti ◽  
Sofia Giorgetti ◽  
Loredana Marchese ◽  
...  
Keyword(s):  
Amyloid Fibrils ◽  
Β2 Microglobulin
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