scholarly journals Photo-reactive oligodeoxynucleotide-embedded nanovesicles (PROsomes) with switchable stability for efficient cellular uptake and gene knockdown

2020 ◽  
Vol 56 (66) ◽  
pp. 9477-9480
Author(s):  
Beob Soo Kim ◽  
Mitsuru Naito ◽  
Rimpei Kamegawa ◽  
Hyun Jin Kim ◽  
Ryo Iizuka ◽  
...  
Keyword(s):  
Cellular Uptake ◽  
Gene Knockdown ◽  
Antisense Oligodeoxynucleotides ◽  
Polyion Complex

A photo-responsive nanovesicle (PROsome) is fabricated via polyion complex between PEG-polypeptides and photo-reactive/antisense oligodeoxynucleotides (PROs/ASOs), eliciting the switchable stability for efficient cellular uptake and gene knockdown.

Cellular uptake of antisense oligodeoxynucleotides

1991 ◽  
Vol 6 (3) ◽  
pp. 235-250 ◽  
Author(s):  
Jerzy W. Jaroszewski ◽  
Jack S. Cohen
Keyword(s):  
Cellular Uptake ◽  
Antisense Oligodeoxynucleotides

Grafting multi-maleimides on antisense oligonucleotide to enhance its cellular uptake and gene silencing capability

2020 ◽  
Vol 56 (54) ◽  
pp. 7439-7442
Author(s):  
Yuanyuan Guo ◽  
Jiao Zhang ◽  
Gaifang Pan ◽  
Chung Hang Jonathan Choi ◽  
Ping Wang ◽  
...  
Keyword(s):  
Membrane Proteins ◽  
Gene Silencing ◽  
Cellular Uptake ◽  
Antisense Oligonucleotide ◽  
Gene Knockdown ◽  
Cell Internalization

Grafting multi-maleimides on antisense oligonucleotide enables its click conjugation to membrane proteins, inducing promoted non-endocytic cell internalization and gene knockdown.

Installation of a Thermoswitchable Hydrophobic Domain into a Unimer Polyion Complex for Enhanced Cellular Uptake of siRNA

2020 ◽  
Vol 31 (5) ◽  
pp. 1320-1326 ◽  
Author(s):  
Beob Soo Kim ◽  
Shigehito Osawa ◽  
Jongmin Yum ◽  
Mitsuru Naito ◽  
Kanjiro Miyata
Keyword(s):  
Cellular Uptake ◽  
Hydrophobic Domain ◽  
Polyion Complex

Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents

2020 ◽  
Vol 56 (65) ◽  
pp. 9332-9335
Author(s):  
Sandra Estalayo-Adrián ◽  
Salvador Blasco ◽  
Sandra A. Bright ◽  
Gavin J. McManus ◽  
Guillermo Orellana ◽  
...  
Keyword(s):  
Cervical Cancer ◽  
Cancer Cells ◽  
Cellular Uptake ◽  
Therapeutic Agents ◽  
Water Soluble ◽  
Polypyridyl Complexes ◽  
Cervical Cancer Cells

Two new water-soluble amphiphilic Ru(ii) polypyridyl complexes were synthesised and their photophysical and photobiological properties evaluated; both complexes showed a rapid cellular uptake and phototoxicity against HeLa cervical cancer cells.

273: Knock-Down of BCL-2 By Antisense Oligodeoxynucleotides Induces Radiosensitization and Inhibition of Angiogenesis

2007 ◽  
Vol 177 (4S) ◽  
pp. 91-92
Author(s):  
Satoshi Anai ◽  
Yoshihisa Sakai ◽  
Steve Goodison ◽  
Kathleen Shiverick ◽  
Bob Brown ◽  
...  
Keyword(s):  
Antisense Oligodeoxynucleotides ◽  
Knock Down ◽  
Inhibition Of Angiogenesis

Neuroprotective effect of antisense oligodeoxynucleotides in experimental intracerebral hemorrhage in rats

2005 ◽  
Vol 25 (1_suppl) ◽  
pp. S505-S505
Author(s):  
Huijin Yan ◽  
Mengzhou Xue ◽  
Christopher Power ◽  
Marc R Del-Bigio ◽  
James Peeling
Keyword(s):  
Intracerebral Hemorrhage ◽  
Neuroprotective Effect ◽  
Antisense Oligodeoxynucleotides
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