scholarly journals Sequence-directed dynamic covalent assembly of base-4-encoded oligomers

2020 ◽  
Vol 56 (56) ◽  
pp. 7817-7820 ◽  
Author(s):  
S. C. Leguizamon ◽  
M. F. Dunn ◽  
T. F. Scott
Keyword(s):  
Aqueous Environment ◽  
Self Assembled ◽  
Reactant Pairs

Molecular ladders and molecular grids were self-assembled employing two orthogonal dynamic covalent reactant pairs in an aqueous environment.

Fluorescent signal transduction in a self-assembled Hg2+ chemosensor tuned by various interactions in micellar aqueous environment

2020 ◽  
Vol 389 ◽  
pp. 112276 ◽  
Author(s):  
Raimondo Germani ◽  
Paola Anastasio ◽  
Michele Chiodini ◽  
Tiziana Del Giacco ◽  
Matteo Tiecco ◽  
...  
Keyword(s):  
Signal Transduction ◽  
Aqueous Environment ◽  
Fluorescent Signal ◽  
Self Assembled

Self-assembled, optically-active {naphthalene diimide}U{cucurbit[8]uril} ensembles in an aqueous environment

2021 ◽  
Author(s):  
Heather Higginbotham ◽  
Subashani Maniam ◽  
Tina Hsia ◽  
Lyle D. Isaacs ◽  
Steven J Langford ◽  
...  
Keyword(s):  
Supramolecular Complex ◽  
Optically Active ◽  
Aqueous Environment ◽  
Naphthalene Diimide ◽  
Non Covalent Interactions ◽  
Self Assembled ◽  
Naphthalene Diimides ◽  
Covalent Interactions

Naphthalene diimides (NDIs) are shown to arrange spontaneously co-facially with cucurbit[8]uril (CB[8]) in an aqueous environment through purely non-covalent interactions. The resultant 2:2 supramolecular complex of NDI and CB[8] is...

IR820 covalently linked with self-assembled polypeptide for photothermal therapy applications in cancer

2018 ◽  
Vol 6 (11) ◽  
pp. 2925-2931 ◽  
Author(s):  
Kaizong Huang ◽  
Mengyue Gao ◽  
Lin Fan ◽  
Yueyang Lai ◽  
Hongwei Fan ◽  
...  
Keyword(s):  
Self Assembly ◽  
Photothermal Therapy ◽  
Aqueous Environment ◽  
Zinc Ions ◽  
Tumor Site ◽  
Self Assembled ◽  
Covalently Linked

Elastin-like polypeptide covalently was linked with IR820 in an aqueous environment, followed by self-assembly into nanoparticles after adding to zinc ions solution. ELP-IR820 nanoparticles significantly accumulated at the tumor site.

Prospects for scanned-probe microscopy

1994 ◽  
Vol 52 ◽  
pp. 6-7
Author(s):  
Jean-Paul Revel
Keyword(s):  
High Vacuum ◽  
Physiological Saline ◽  
Scanning Probe ◽  
Aqueous Environment ◽  
Whole Cells ◽  
Material Scientist ◽  
Biological Objects ◽  
Spatially Resolved ◽  
Atomic Force ◽  
Scanned Probe Microscopy

In the last 50+ years the electron microscope and allied instruments have led the way as means to acquire spatially resolved information about very small objects. For the material scientist and the biologist both, imaging using the information derived from the interaction of electrons with the objects of their concern, has had limitations. Material scientists have been handicapped by the fact that their samples are often too thick for penetration without using million volt instruments. Biologists have been handicapped both by the problem of contrast since most biological objects are composed of elements of low Z, and also by the requirement that sample be placed in high vacuum. Cells consist of 90% water, so elaborate precautions have to be taken to remove the water without losing the structure altogether. We are now poised to make another leap forwards because of the development of scanned probe microscopies, particularly the Atomic Force Microscope (AFM). The scanning probe instruments permit resolutions that electron microscopists still work very hard to achieve, if they have reached it yet. Probably the most interesting feature of the AFM technology, for the biologist in any case, is that it has opened the dream of high resolution in an aqueous environment. There are few restrictions on where the instrument can be used. AFMs can be made to work in high vacuum, allowing the material scientist to avoid contamination. The biologist can be made happy as well. The tips used for detection are made of silicon nitride,(Si3N4), and are essentially unaffected by exposure to physiological saline (about which more below). So here is an instrument which can look at living whole cells and at atoms as well.

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