Nanoscale insight into the degradation mechanisms of the cartilage articulating surface preceding OA

2020 ◽  
Vol 8 (14) ◽  
pp. 3944-3955 ◽  
Author(s):  
Tooba Shoaib ◽  
Catherine Yuh ◽  
Markus A. Wimmer ◽  
Thomas M. Schmid ◽  
Rosa M. Espinosa-Marzal

Osteoarthritis (OA) is a degenerative disease and leading cause of disability globally. We report the a fundamental study of the mechanisms underlying deterioration of hydrated cartilage in the presence of elevated calcium content preceding OA.

2020 ◽  
Vol 8 (16) ◽  
pp. 4642-4642
Author(s):  
Tooba Shoaib ◽  
Catherine Yuh ◽  
Markus A. Wimmer ◽  
Thomas M. Schmid ◽  
Rosa M. Espinosa-Marzal

Correction for ‘Nanoscale insight into the degradation mechanisms of the cartilage articulating surface preceding OA’ by Tooba Shoaib, et al., Biomater. Sci., 2020, 8, 3944–3955, DOI: 10.1039/D0BM00496K.


2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
Shuxiang Geng ◽  
Delu Ning ◽  
Ting Ma ◽  
Haiyun Chen ◽  
Yinzhi Zhang ◽  
...  

The contents of main components in 45 walnut kernels from 5 walnut-planting provinces in China (Yunnan, Shaanxi, Shandong, Hebei, and Sichuan) were determined using colorimetry, high-performance liquid chromatography, and gas chromatography, including flavonoids, vitamin E, trace elements, fatty acids, and amino acids. The levels of flavonoids and vitamin E were higher in walnuts from Yunnan than in walnuts from the other four provinces. The levels of zinc and iron were relatively higher in walnuts from Shandong, and the calcium content in walnuts from Yunnan was much lower. No obvious difference was found in crude fat concentration for nuts from the five provinces, but differences were observed in the crude protein content. Oleic acid was the predominant unsaturated fatty acids in all walnut species; the monounsaturated fatty acid content was the highest in walnuts from Yunnan. The data obtained here provided insight into differences in walnuts resulting from different growing environments and germplasm genetic traits.


2019 ◽  
Vol 11 (33) ◽  
pp. 29725-29735 ◽  
Author(s):  
Carles Ros ◽  
Nina M. Carretero ◽  
Jeremy David ◽  
Jordi Arbiol ◽  
Teresa Andreu ◽  
...  

Life ◽  
2018 ◽  
Vol 8 (4) ◽  
pp. 56 ◽  
Author(s):  
Teresa Fornaro ◽  
Andrew Steele ◽  
John Brucato

Minerals might have played critical roles for the origin and evolution of possible life forms on Mars. The study of the interactions between the “building blocks of life” and minerals relevant to Mars mineralogy under conditions mimicking the harsh Martian environment may provide key insight into possible prebiotic processes. Therefore, this contribution aims at reviewing the most important investigations carried out so far about the catalytic/protective properties of Martian minerals toward molecular biosignatures under Martian-like conditions. Overall, it turns out that the fate of molecular biosignatures on Mars depends on a delicate balance between multiple preservation and degradation mechanisms, often regulated by minerals, which may take place simultaneously. Such a complexity requires more efforts in simulating realistically the Martian environment in order to better inspect plausible prebiotic pathways and shed light on the nature of the organic compounds detected both in meteorites and on the surface of Mars through in situ analysis.


2020 ◽  
Vol 2 (7) ◽  
pp. 2686-2695 ◽  
Author(s):  
Amélie Schultheiss ◽  
Magatte Gueye ◽  
Alexandre Carella ◽  
Anass Benayad ◽  
Stéphanie Pouget ◽  
...  

2020 ◽  
Vol 11 (4) ◽  
pp. 2805-2825 ◽  
Author(s):  
Javier Quero ◽  
Inés Mármol ◽  
Elena Cerrada ◽  
María Jesús Rodríguez-Yoldi

In recent times, a great number of plants have been studied in order to identify new components with nutraceutical properties, among which are polyphenols.


Author(s):  
Teresa Fornaro ◽  
Andrew Steele ◽  
John Robert Brucato

Minerals might have played critical roles for the origin and evolution of possible life forms on Mars. The study of the interactions between “building blocks of life” and minerals relevant to Mars mineralogy under conditions mimicking the harsh Martian environment may provide key insight into possible prebiotic processes. Therefore, this contribution aims at reviewing the most important investigations carried out so far about the catalytic/protective properties of Martian minerals toward molecular biosignatures under Martian-like conditions. Overall, it turns out that the fate of molecular biosignatures on Mars depends on a delicate balance between multiple preservation and degradation mechanisms often regulated by minerals, which may take place simultaneously. Such a complexity requires more efforts in simulating realistically the Martian environment in order to better inspect plausible prebiotic pathways and shed light on the nature of the organic compounds detected both in meteorites and on the surface of Mars through in situ analysis.


2021 ◽  
Author(s):  
Artur Neves ◽  
Maria João Melo ◽  
Ana Maria Ramos ◽  
Maria Elvira Callapez ◽  
Robert Friedel ◽  
...  

Abstract Cellulose nitrate (CN) is an intrinsically unstable material that puts at risk the preservation of a great variety of objects in heritage collections, also posing threats to human health. For this reason, a detailed investigation of its degradation mechanisms is necessary to develop sustainable conservation strategies. To investigate novel probes of degradation, we implemented deep UV photoluminescence micro spectral-imaging, for the first time, to characterize a corpus of historical systems composed of cellulose nitrate. The analysis of cinematographic films and everyday objects dated from the 19th c. / early 20th c. (Perlov's collection), as well as of photo-aged CN and celluloid references allowed the identification of novel markers that correlate with different phases of CN degradation in artworks, providing insight into the role played by plasticizers, fillers, and other additives instability. By comparison with photoaged references of CN and celluloid (70% CN and 30% camphor), it was possible to correlate camphor concentration with a higher rate of degradation of the cinematographic films. Furthermore, the present study investigates, at the sub-microscale, materials heterogeneity that correlates to the artworks' history, associating the different emission profiles of zinc oxide to specific color formulations used in the late 19th and early 20th centuries.


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