scholarly journals Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis

2020 ◽  
Vol 8 (16) ◽  
pp. 4467-4480
Author(s):  
Joanna R. Stasiak ◽  
Marta Serrani ◽  
Eugenia Biral ◽  
James V. Taylor ◽  
Azfar G. Zaman ◽  
...  
Keyword(s):  
Heart Valve ◽  
Feasibility Study ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Design Development ◽  
Iso Standards ◽  
Bench Testing ◽  
Bioprosthetic Valves

A novel polymeric heart valve shows durability equivalent to 25 years in accelerated bench testing, in vitro hydrodynamics equivalent to existing bioprosthetic valves; and good performance in a small acute feasibility study in sheep.

scholarly journals Correction: Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis

2020 ◽  
Vol 8 (16) ◽  
pp. 4639-4639
Author(s):  
Joanna R. Stasiak ◽  
Marta Serrani ◽  
Eugenia Biral ◽  
James V. Taylor ◽  
Azfar G. Zaman ◽  
...  
Keyword(s):  
Heart Valve ◽  
Feasibility Study ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Design Development ◽  
Iso Standards

Correction for ‘Design, development, testing at ISO standards and in vivo feasibility study of a novel polymeric heart valve prosthesis’ by Joanna R. Stasiak et al., Biomater. Sci., 2020, DOI: 10.1039/d0bm00412j.

In vivo Platelet Release Reaction in Patients with Heart Valve Prosthesis

1980 ◽  
Vol 9 (5) ◽  
pp. 263-275
Author(s):  
G. Cella ◽  
L. Schivazappa ◽  
A. Casonato ◽  
L.G. Molaro ◽  
A. Girolami ◽  
...  
Keyword(s):  
Heart Valve ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Release Reaction ◽  
Platelet Release

In Vivo Evaluation of the Lillehei-Kaster Heart Valve Prosthesis

1976 ◽  
Vol 22 (3) ◽  
pp. 213-220 ◽  
Author(s):  
U. Sigwart ◽  
H. Schmidt ◽  
U. Gleichmann ◽  
H.G. Borst
Keyword(s):  
Heart Valve ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
In Vivo Evaluation

In vitro haemocompatibility and cytocompatibility evaluation of silver thin film-deposited heart valve prosthesis material

2019 ◽  
Vol 34 (8) ◽  
pp. 471-479 ◽  
Author(s):  
J. Tracy Tina Angelina ◽  
R. Narayani ◽  
S. Ganesan ◽  
T. M. R. Panicker ◽  
K. Jagadeesan
Keyword(s):  
Thin Film ◽  
Heart Valve ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Silver Thin Film ◽  
Prosthesis Material

In Vitro Fluid Dynamic Characteristics of the Medtronic-Hall Pivoting Disc Heart Valve Prosthesis

1982 ◽  
Vol 16 (3) ◽  
pp. 235-243 ◽  
Author(s):  
Ajit P. Yoganathan ◽  
Dana M. Stevenson ◽  
Frank P. Williams ◽  
Yi-Ren Woo ◽  
Robert H. Franch ◽  
...  
Keyword(s):  
Heart Valve ◽  
Dynamic Characteristics ◽  
Fluid Dynamic ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis

Design and in Vitro Performance of a Novel Bileaflet Mechanical Heart Valve Prosthesis

2005 ◽  
Vol 28 (3) ◽  
pp. 256-263 ◽  
Author(s):  
D. Medart ◽  
C. Schmitz ◽  
G. Rau ◽  
H. Reul
Keyword(s):  
Heart Valve ◽  
Mechanical Heart Valve ◽  
Polymeric Materials ◽  
Hydrodynamic Performance ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Suitable Material ◽  
Bileaflet Mechanical Heart Valve ◽  
In Vitro Performance

Design and in vitro performance of a novel bileaflet mechanical heart valve prosthesis are presented. The novel heart valve exhibits three main design characteristics: (i) The leaflets form a Venturi passage in open position. Thus, a beneficial pressure distribution is obtained and the leaflets are stabilised in opened position. (ii) The orifice inlet is nozzle-shaped. Flow is convectively accelerated and flow separation at the orifice inlet is avoided. (iii) The hinge design facilitates an additional axial movement of the leaflets and leads to a self cleaning effect and enhances washout of the hinges. The design of the leaflet hinges is of main importance for the functional reliability and durability of mechanical heart valves. After manufacturing first prototypes from titanium and polymeric materials the hydrodynamic performance was evaluated according to ISO 5840 and FDA guidelines. Hydrodynamic performance is comparable with the results of commonly available bileaflet mechanical heart valve prostheses. Initial durability tests showed suitable material couples for further long term studies.

In Vitro Function and Durability Assessment of a Novel Polyurethane Heart Valve Prosthesis

1996 ◽  
Vol 20 (9) ◽  
pp. 1017-1025 ◽  
Author(s):  
T.G. Mackay ◽  
G.M. Bernacca ◽  
A.C. Fisher ◽  
C.S. Hindle ◽  
D.J. Wheatley
Keyword(s):  
Heart Valve ◽  
Heart Valve Prosthesis ◽  
Valve Prosthesis ◽  
Durability Assessment

The Clinical Aspects of Heart Valve Replacement: An Overview

1987 ◽  
Vol 16 (2) ◽  
pp. 63-65
Author(s):  
K M Taylor
Keyword(s):  
Heart Valve ◽  
Clinical Aspects ◽  
Valve Prosthesis ◽  
Objective Data ◽  
The Past ◽  
In Vivo Testing ◽  
Cardiac Surgeons ◽  
Meaningful Data

Cardiac surgeons have to start from the basis that no perfect heart valve prosthesis presently exists. In the past few years a number of heart valve substitutes have been released for clinical implantation with little objective data to support their clinical acceptability. Uncertainty exists in the minds of many cardiac surgeons in interpreting results of in vitro and in vivo testing. Confusion has been increased by the tendency of many units to implant a small number of a variety of different heart valve substitutes, thus losing the opportunity for meaningful data. Further progress in the understanding and development of better heart valve substitutes will require a disciplined approach, both to in vitro and in vivo testing.

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