Overview of the application of inorganic nanomaterials in cancer photothermal therapy

2020 ◽  
Vol 8 (11) ◽  
pp. 2990-3020 ◽  
Author(s):  
Natanael Fernandes ◽  
Carolina F. Rodrigues ◽  
André F. Moreira ◽  
Ilídio J. Correia
Keyword(s):  
Therapeutic Effect ◽  
Photothermal Therapy ◽  
Inorganic Nanomaterials

Cancer photothermal therapy (PTT) has captured the attention of researchers worldwide due to its localized and trigger-activated therapeutic effect.

Near-infrared Inorganic Nanomaterials-based Nanosystem for Photothermal Therapy

Nanoscale ◽  
2021 ◽  
Author(s):  
Yufei Wang ◽  
Hongmin Meng ◽  
Zhaohui Li
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Strong Absorption ◽  
Non Invasive ◽  
Inorganic Nanomaterials

The development of robust materials for treating diseases through non-invasive photothermal therapy (PTT) has attracted increasing attention in recent years. Among many types of nanomaterials, inorganic nanomaterials with strong absorption...

scholarly journals A tumor-microenvironment-responsive nanomaterial for cancer chemo-photothermal therapy

RSC Advances ◽  
2020 ◽  
Vol 10 (37) ◽  
pp. 22091-22101
Author(s):  
Kaiyu Wang ◽  
Zhiyuan Cai ◽  
Rong Fan ◽  
Qian Yang ◽  
Tao Zhu ◽  
...  
Keyword(s):  
Hydrogen Peroxide ◽  
Tumor Microenvironment ◽  
Therapeutic Effect ◽  
Photothermal Therapy

Endogenous hydrogen peroxide was utilized to control the release of agents for better tumor therapeutic effect and safety.

NIR-controlled HSP90 inhibitor release from hollow mesoporous nanocarbon for synergistic tumor photothermal therapy guided by photoacoustic imaging

Nanoscale ◽  
2020 ◽  
Vol 12 (27) ◽  
pp. 14775-14787
Author(s):  
Jiaxin Sun ◽  
Yongjing Li ◽  
Yilong Teng ◽  
Sheng Wang ◽  
Jia Guo ◽  
...  
Keyword(s):  
Therapeutic Effect ◽  
Photothermal Therapy ◽  
Mesoporous Carbon ◽  
Photoacoustic Imaging ◽  
Drug Carriers ◽  
Hsp90 Inhibitor ◽  
Carbon Nanospheres ◽  
Mild Temperature

Hollow mesoporous carbon nanospheres were used as drug carriers for mild-temperature photothermal therapy, which showed a significant NIR-enhanced synergistic tumor therapeutic effect guided by photoacoustic imaging.

scholarly journals Bioinspired carrier-free peptide conjugated BF2-oxasmaragdyrin dye-based nano self-assemblies: a photostable NIR cancer theragnostic agent

2020 ◽  
Vol 12 (1) ◽  
Author(s):  
Kandala Laxman ◽  
B. Pradeep K. Reddy ◽  
Sumit K. Mishra ◽  
Andrea Robinson ◽  
Abhijit De ◽  
...  
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Visible Region ◽  
Whole Body ◽  
Water Mixture ◽  
Free Peptide ◽  
Nirf Imaging ◽  
Nir Fluorescence ◽  
Inorganic Nanomaterials

AbstractPhotothermal therapy (PTT) has attracted great interest in cancer treatment, and the quest for potential organic photothermal agents is underway owing to the nonbiodegradable nature and chronic toxicity of existing inorganic nanomaterials. Organic material-based nanoformulations with good photothermal and fluorescence properties in the near-infrared (NIR-I) window are scarce. However, porphyrins are one category of biocompatible systems that are advantageous for photothermal therapy but are currently based in the visible region, causing limited depth of tissue penetration and leading to compromised photothermal and near-infrared fluorescence (NIRF) imaging applications. To overcome these limitations, we report the synthesis of L,L-diphenylalanine conjugated BF2-oxasmaragdyrin (FF-BSC) and the fabrication of monodispersed spherical self-assemblies (FF-BSC NPs) using a USP class 3 solvent-water mixture. The resulting product exhibited excellent photostability (NIR exposure), multicycle photothermal efficacy, and NIR fluorescence. In vitro studies revealed good biocompatibility, efficient cellular internalization, and photothermal efficacy. Preclinical studies of these nano-self-assemblies demonstrated nontoxicity, efficient whole-body NIRF imaging, fractional passive tumor homing, and excellent photothermal tumor ablation potential. The absorbance and fluorescence of FF-BSC NPs in NIR-I make them suitable for theragnostic applications over existing porphyrins/inorganic nanomaterials for future clinical applications.

scholarly journals Research on Targeted Thermal Effect of Molybdenum Disulfide Nanosheets Modified by Nucleic Acid Aptamers

2020 ◽  
Vol 185 ◽  
pp. 04003
Author(s):  
Bo pang ◽  
Lihong Jin ◽  
Liying Wang
Keyword(s):  
Nucleic Acid ◽  
Molybdenum Disulfide ◽  
Therapeutic Effect ◽  
Photothermal Therapy ◽  
Effective Concentration ◽  
Tumor Treatment ◽  
Nucleic Acid Aptamers ◽  
Low Toxicity ◽  
Good Biocompatibility ◽  
Molybdenum Disulfide Nanosheets

In this paper, the surface of molybdenum disulfide nanosheets synthesized by hydrothermal method was modified with bovine serum albumin (BSA) and nucleic acid aptamers in order to construct a photothermal system with high target recognition, stable size, good biocompatibility and low toxicity Nano material molybdenum disulfide; Under 808 nm laser irradiation, suitable functionalized molybdenum disulfide nanosheets can produce singlet oxygen at an effective concentration for photodynamic therapy, and at the same time, photothermal therapy can also be used to achieve synergistic therapy and the therapeutic effect is more excellent. This shows that such functionalized molybdenum disulfide nanosheets have excellent therapeutic effect and great potential in tumor treatment.

Flower-like Fe7S8/Bi2S3 superstructures with improved near-infrared absorption for efficient chemo-photothermal therapy

2019 ◽  
Vol 48 (10) ◽  
pp. 3360-3368 ◽  
Author(s):  
Qing Cao ◽  
Xin Guo ◽  
Wenlong Zhang ◽  
Guoqiang Guan ◽  
Xiaojuan Huang ◽  
...  
Keyword(s):  
Therapeutic Effect ◽  
Infrared Absorption ◽  
Photothermal Therapy ◽  
Near Infrared

Hydrophilic flower-like Fe7S8/Bi2S3 superstructures with improved near-infrared absorption and photostability for good chemo-photothermal synergistic therapeutic effect.

Activatable UCL/CT/MR-Enhanced in vivo Imaging-Guided Radiotherapy and Photothermal Therapy

2022 ◽  
Author(s):  
Jianming Ni ◽  
Huiting Xu ◽  
Yanqi Zhong ◽  
Yongping Zhou ◽  
Shudong Hu
Keyword(s):  
Tumor Microenvironment ◽  
Therapeutic Effect ◽  
In Vivo Imaging ◽  
Photothermal Therapy ◽  
Copper Sulphide ◽  
Hypoxic Tumor

Although sophisticated radiotherapy (RT) technology has been widely applied in clinical oncotherapy, unsatisfactory therapeutic effect resulted by hypoxic tumor microenvironment and complications are still prevalent. Herein, copper sulphide nanoparticles (CuS...

scholarly journals Theranostic CuS nanoparticles targeting folate receptors for PET image-guided photothermal therapy

2015 ◽  
Vol 3 (46) ◽  
pp. 8939-8948 ◽  
Author(s):  
Min Zhou ◽  
Shaoli Song ◽  
Jun Zhao ◽  
Mei Tian ◽  
Chun Li
Keyword(s):  
Therapeutic Effect ◽  
Infrared Absorption ◽  
Pet Imaging ◽  
Photothermal Therapy ◽  
Near Infrared ◽  
Tumor Uptake ◽  
Folate Receptors ◽  
Image Guided

Targeted FA–CuS NPs can significantly improve the tumor uptake; the integration of 64Cu into NPs with strong near-infrared absorption makes them suitable for PET imaging, and image-guided photothermal therapy; targeted FA–CuS NPs mediate a substantially greater therapeutic effect compared with photothermal therapy with non-targeted CuS NPs.

scholarly journals Near-infrared light-responsive inorganic nanomaterials for photothermal therapy

2016 ◽  
Vol 11 (3) ◽  
pp. 349-364 ◽  
Author(s):  
Zhihong Bao ◽  
Xuerong Liu ◽  
Yangdi Liu ◽  
Hongzhuo Liu ◽  
Kun Zhao
Keyword(s):  
Photothermal Therapy ◽  
Near Infrared ◽  
Infrared Light ◽  
Near Infrared Light ◽  
Inorganic Nanomaterials

scholarly journals Inorganic nanomaterials for chemo/photothermal therapy: a promising horizon on effective cancer treatment

2019 ◽  
Vol 11 (3) ◽  
pp. 335-352 ◽  
Author(s):  
Mona Khafaji ◽  
Masoud Zamani ◽  
Mortaza Golizadeh ◽  
Omid Bavi
Keyword(s):  
Cancer Treatment ◽  
Photothermal Therapy ◽  
Inorganic Nanomaterials
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