A Fe3+-crosslinked pyrogallol-tethered gelatin adhesive hydrogel with antibacterial activity for wound healing

2020 ◽  
Vol 8 (11) ◽  
pp. 3164-3172 ◽  
Author(s):  
Ning Han ◽  
Ziyang Xu ◽  
Chunyan Cui ◽  
Yuan Li ◽  
Dongfei Zhang ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Strong Adhesion ◽  
Mixing Method ◽  
Antibacterial Capacity

A tunicate-inspired gelatin-based hydrogel prepared by a simple mixing method, exhibits strong adhesion and antibacterial capacity, and facilitates wound healing.

APPLICATIONS OF CHITOSAN-SULFATHIAZOLE AS ANTIMICROBIAL AGENT

2018 ◽  
Vol 28 (2) ◽  
pp. 429-432
Author(s):  
Dilyana Zvezdova
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Fourier Transform ◽  
Infrared Spectroscopy ◽  
Antimicrobial Agent ◽  
Defense Mechanisms ◽  
Solvent Casting ◽  
Casting Method ◽  
Gram Negative ◽  
Positively Charged

Chitosan, a hydrophilic biopolymer industrially obtained by N-deacetylation of chitin, can be applied as an antimicrobial agent. It highlights the applications of chitosan as an antimicrobial agent against fungi, bacteria, and viruses and as an elicitor of plant defense mechanisms. A series of novel chitosan-sulfathiazole nanocomposite (CSFZ) films were prepared by using solvent casting method for wound healing application. Fourier transform infrared spectroscopy (FTIR) was employed to ascertain the interaction between negatively charged sulfathiazole and positively charged chitosan. Moreover, the antibacterial activity of the films was investigated against gram positive and gram negative microorganisms. It was found that all CSFZ films showed good inhibitory activity against all the tested bacteria as compared to control. The above analysis suggested that the CSFZ films could be used as potential candidates for wound healing application.

A moisture balanced antibacterial dressing loaded with lysozyme possesses antibacterial activity and promotes wound healing

Soft Matter ◽  
2021 ◽  
Vol 17 (11) ◽  
pp. 3162-3173
Author(s):  
Ling Xiao ◽  
Wenqiang Ni ◽  
Xiaohong Zhao ◽  
Yicheng Guo ◽  
Xue Li ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Promote Wound Healing

An antibacterial moisture balanced dressing is designed to fight infection and promote wound healing.

scholarly journals The Wound Healing and Antibacterial Activity of Five Ethnomedical Calophyllum inophyllum Oils: An Alternative Therapeutic Strategy to Treat Infected Wounds

PLoS ONE ◽  
2015 ◽  
Vol 10 (9) ◽  
pp. e0138602 ◽  
Author(s):  
Teddy Léguillier ◽  
Marylin Lecsö-Bornet ◽  
Christelle Lémus ◽  
Delphine Rousseau-Ralliard ◽  
Nicolas Lebouvier ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Therapeutic Strategy ◽  
Calophyllum Inophyllum ◽  
Infected Wounds

scholarly journals Wound healing activity of Conyza canadensis (L.) Cronquist

2018 ◽  
Vol 1 (T5) ◽  
pp. 35-40
Author(s):  
To Dinh Le ◽  
Nga Thi Hoang ◽  
Nhan Thi Thanh Nguyen ◽  
Thuoc Linh Tran ◽  
Thao Thi Phuong Dang
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Ethyl Acetate ◽  
National Park ◽  
Ethanolic Extract ◽  
Ethyl Acetate Fraction ◽  
Conyza Canadensis ◽  
Keratinocyte Proliferation ◽  
Wound Healing Activity ◽  
Stimulation Of

Conyza canadensis (L.) Cronquist (CCL) has been used by K’Ho minority in Bidoup Nui Ba national park, Lam Dong province, Vietnam as one of wound healing remedies. However, the scientific proof of treatment is still unclear. This study aimed to evaluate this wound healing potential of CCL. CCL power was extracted by ethanol and then partitioned consecutively with petroleum ether, ethyl acetate and water. Wound healing potential was evaluated by antibacterial activity, stimulation of fibroblast and keratinocyte proliferation. Agar-well diffusion was used in the antibacterial tests and the results showed that CCL had antibacterial activity against 02 dermatitis bacteria (Pseudomonas aeruginosa, Staphylococcus aureus) and 02 opportunistic infection bacteria (Escherichia coli, Enterococcus faecalis). Moreover, our results illustrated that CCL stimulated the fibroblast and keratinocyte proliferation compared to the control. Particularly, the fibroblast division increased 1.6 times at 31.25 µg/mL when treated by ethanolic extract, while ethyl acetate fraction showed 1.7 times increase at 10 µg/mL in keratinocyte proliferation compared to the control. Taken together, our study contributed scientific base of CCL in the wound healing.

Structure and Properties of Chitosan Containing Polyacrylic Acid Hydrogel Grafted SMS Nonwovens

2009 ◽  
Vol 87-88 ◽  
pp. 513-517 ◽  
Author(s):  
Xu Pin Zhuang ◽  
Wen Jian Deng ◽  
Bo Wen Cheng
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Acrylic Acid ◽  
Water Absorption ◽  
Ammonium Nitrate ◽  
Polyacrylic Acid ◽  
Structure And Properties ◽  
Second Stage ◽  
Xps Spectroscopy ◽  
Potassium Peroxydisulfate

Hydrogels donate moisture to dehydrated tissue and absorb some moisture and accepted in wound healing. Polypropylene (PP) SMS nonwovens were grafted polyacrylic acid (PAA) hydrogel technique contanining chitosan to enhance hydrophilicity and antibacterial activity. In the first stage, nonwovens were hydroxylated by treatment with aqueous potassium peroxydisulfate solution under a strong flow of nitrogen. In the second stage, the hydroxylated nonwovens were subjected to grafting of acrylic acid using cerric ammonium nitrate as an initiator. Subsequently, chitosan was grafted onto the modified NWs with N,N'-Methylenebisacrylamide. The modified nonwovens were characterized by XPS spectroscopy and SEM, the results showed that acrylic acid was copolymerized and hydrogel grafted onto SMS nonwovens. Hydrogel grafted nonwovens exhibited enhanced wettability and water absorption ability. With introduce of chitosan further, the modified NWs exhibited effectively antibacterial activity against E.coli.

Silver Inlaid with Gold Nanoparticle/Chitosan Wound Dressing Enhances Antibacterial Activity and Porosity, and Promotes Wound Healing

2017 ◽  
Vol 18 (11) ◽  
pp. 3766-3775 ◽  
Author(s):  
Qing Li ◽  
Fei Lu ◽  
Guofang Zhou ◽  
Kun Yu ◽  
Bitao Lu ◽  
...  
Keyword(s):  
Wound Healing ◽  
Antibacterial Activity ◽  
Gold Nanoparticle ◽  
Wound Dressing
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