Gold leaf electrochemical sensors: applications and nanostructure modification

The Analyst ◽  
2021 ◽  
Vol 146 (5) ◽  
pp. 1579-1589
Author(s):  
Paithoon Prasertying ◽  
Nanthatchaphon Jantawong ◽  
Thitaporn Sonsa-ard ◽  
Thinnapong Wongpakdee ◽  
Nuttamon Khoonrueng ◽  
...  
Keyword(s):  
Electrochemical Sensors ◽  
Structure Modification ◽  
Gunshot Residues ◽  
Gold Leaf ◽  
Site Identification

A gold leaf sensor with structure modification enabling on-site identification of types of bullet from gunshot residues.

Evaluation of the Simultaneous Analysis of Organic and Inorganic Gunshot Residues Within a Large Population Data Set Using Electrochemical Sensors* , †

2020 ◽  
Vol 65 (6) ◽  
pp. 1935-1944 ◽  
Author(s):  
Colby E. Ott ◽  
Kourtney A. Dalzell ◽  
Pedro José Calderón‐Arce ◽  
Ana Lorena Alvarado‐Gámez ◽  
Tatiana Trejos ◽  
...  
Keyword(s):  
Electrochemical Sensors ◽  
Large Population ◽  
Population Data ◽  
Simultaneous Analysis ◽  
Data Set ◽  
Gunshot Residues

scholarly journals Portable Electrochemical Detection of Illicit Drugs in Smuggled Samples: Towards More Secure Borders

2021 ◽  
Vol 5 (1) ◽  
pp. 44
Author(s):  
Marc Parrilla ◽  
Amorn Slosse ◽  
Robin Van Echelpoel ◽  
Noelia Felipe Montiel ◽  
Filip Van Durme ◽  
...  
Keyword(s):  
Electrochemical Detection ◽  
Illicit Drugs ◽  
Electrochemical Sensors ◽  
Low Cost ◽  
Spectroscopic Techniques ◽  
Health Issues ◽  
Promising Alternative ◽  
Border Trade ◽  
Site Identification ◽  
User Friendly

Illicit drug consumption is posing critical concerns in our society causing health issues, crime-related activities and the disruption of the border trade. The smuggling of illicit drugs urges the development of new tools for rapid on-site identification in cargos. Current methods used by law enforcement offices rely on presumptive color tests and portable spectroscopic techniques. However, these methods sometimes exhibit inaccurate results due to commonly used cutting agents or because the drugs are smuggled (hidden or mixed) in colored samples. Interestingly, electrochemical sensors can deal with these specific problems. Herein, it is presented an electrochemical device that uses low-cost screen-printed electrodes for the electrochemical detection of illicit drugs by square-wave voltammetry (SWV) profiling. A library of electrochemical profiles is built upon pure and mixtures of illicit drugs with common cutting agents. This library allows the design of a tailor-made script that shows the identification of each drug through a user-friendly interface. Finally, the results obtained from the analysis of different samples from confiscated cargos at an end-user laboratory present a promising alternative to current methods offering low-cost and rapid testing in the field.

Structural, Thermal and Electrical Properties of Doped Poly(3,4 ethylenedioxythiophene)

2016 ◽  
Vol 10 (4) ◽  
pp. 395-400 ◽  
Author(s):  
Deepali Kelkar ◽  
◽  
Ashish Chourasia ◽  
◽  
Keyword(s):  
Crystal Structure ◽  
Electrical Properties ◽  
Xrd Analysis ◽  
Structure Modification ◽  
Camphorsulfonic Acid ◽  
Thermal And Electrical Properties ◽  
Ft Ir

Poly(3,4-ethylenedioxythiophene) (PEDOT) was chemically synthesized, undoped and then re-doped using FeCl3 as well as camphorsulfonic acid (CSA). FT-IR results confirm the nature of the synthesized and doped samples. XRD analysis indicates crystal structure modification after doping and was also used to calculate crystallinity of samples. Crystallinity increases after FeCl3 doping, whereas it reduces due to CSA doping. TGA-DTA results show reduction in Tg value for FeCl3 doped sample while it increases for CSA doped samples compared to that of undoped PEDOT. Reduction in Tg indicates plasticizing effect of FeCl3 whereas increase in Tg show anti-plasticizing effect of CSA in PEDOT. Conductivity value () increases by two orders of magnitude after doping. Log vs. 1/T graph show metallic nature of undoped PEDOT above 308 K, however both doped samples show semiconducting nature from 301 to 383 K.

The design, synthesis, pharmacokinetic and pharmacodynamic evaluation of acyloxyalkyl-substituted T705 prodrugs

2019 ◽  
Vol 15 ◽  
Author(s):  
Xingzhou Li ◽  
Tianhong Zhang ◽  
Wu Zhong
Keyword(s):  
Plasma Concentration ◽  
Development Strategy ◽  
Parent Compound ◽  
Systemic Exposure ◽  
Parent Drug ◽  
New Drugs ◽  
Structure Modification ◽  
Design Synthesis ◽  
Pharmacokinetic Properties

Background: The pharmacokinetic properties of T705 are not optimal for the development of new drugs. Objective: To improve the pharmacokinetic properties of T-705, structure modification of T-705 was conducted using a prodrug strategy. Method: The acidic amide H atom (N4-H) of T705 was attempted to be replaced with acyloxyalkyl groups following the prodrugs development strategy for carboxylic acids, and the resulting compounds were investigated whether could work as prodrugs and contribute to improving the pharmacokinetic properties of the parent compound T705 in vivo. Results: 4-acyloxyalkyl-T705 (4a–e), did act as prodrugs in vivo. 4-iso-butyryloxymethyl-T705 (4a) and 4-acetoxymethyl-T705 (4b) could significantly improve the plasma concentration and systemic exposure for T705, compound 4a displayed non inferior anti-influenza activities, compared with its parent drug T705. Conclusion: Our prodrugs development strategy for T705 is feasible, which may serves as a reference to prodrugs development of similar heterocyclic amides compounds.

Biomimetic Electrochemical Sensors Based on Imprinted Polymers for Determination of Mercury Ion

2016 ◽  
Vol 13 (1) ◽  
pp. 62-69 ◽  
Author(s):  
M. R. Ganjali ◽  
T. Alizadeh ◽  
B. Larijani ◽  
M. Aghazadeh ◽  
E. Pourbasheer ◽  
...  
Keyword(s):  
Electrochemical Sensors ◽  
Mercury Ion ◽  
Imprinted Polymers
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