scholarly journals Nanozyme-based electrochemical biosensors for disease biomarker detection

The Analyst ◽  
2020 ◽  
Vol 145 (13) ◽  
pp. 4398-4420 ◽  
Author(s):  
Rabbee G. Mahmudunnabi ◽  
Fatema Zerin Farhana ◽  
Navid Kashaninejad ◽  
Shakhawat H. Firoz ◽  
Yoon-Bo Shim ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Electrochemical Biosensors ◽  
Biomarker Detection ◽  
Disease Biomarker

In this review, we have summarised the synthesis and classification of common nanozymes and their applications in electrochemical biosensor development.

Biosensors for disease biomarker detection

2012 ◽  
pp. 191-216 ◽  
Author(s):  
B.J. Battersby ◽  
A. Chen ◽  
D. Kozak ◽  
M. Trau
Keyword(s):  
Biomarker Detection ◽  
Disease Biomarker

scholarly journals Porous Alumina Membrane-Based Electrochemical Biosensor for Protein Biomarker Detection in Chronic Wounds

2020 ◽  
Vol 8 ◽  
Author(s):  
Gayathri Rajeev ◽  
Elizabeth Melville ◽  
Allison J. Cowin ◽  
Beatriz Prieto-Simon ◽  
Nicolas H. Voelcker
Keyword(s):  
Chronic Wounds ◽  
Electrochemical Biosensor ◽  
Porous Alumina ◽  
Biomarker Detection ◽  
Alumina Membrane ◽  
Protein Biomarker ◽  
Porous Alumina Membrane

Online electrochemical systems for continuous neurochemical measurements with low-potential mediator-based electrochemical biosensors as selective detectors

The Analyst ◽  
2015 ◽  
Vol 140 (15) ◽  
pp. 5039-5047 ◽  
Author(s):  
Zipin Zhang ◽  
Jie Hao ◽  
Tongfang Xiao ◽  
Ping Yu ◽  
Lanqun Mao
Keyword(s):  
Electron Transfer ◽  
Electrochemical Biosensor ◽  
Electrochemical Biosensors ◽  
Electrochemical Systems ◽  
Potential Mediator ◽  
New Strategy ◽  
Selective Detectors ◽  
Electron Mediators

This study demonstrates a new strategy to develop online electrochemical systems (OECSs) for continuously monitoring neurochemicals by efficiently integrating in vivo microdialysis with an oxidase-based electrochemical biosensor with low-potential electron mediators to shuttle the electron transfer of the oxidases.

scholarly journals Recent Progress in Nanomaterials Modified Electrochemical Biosensors for the Detection of MicroRNA

Micromachines ◽  
2021 ◽  
Vol 12 (11) ◽  
pp. 1409
Author(s):  
Sze Shin Low ◽  
Daizong Ji ◽  
Wai Siong Chai ◽  
Jingjing Liu ◽  
Kuan Shiong Khoo ◽  
...  
Keyword(s):  
Electrochemical Biosensor ◽  
Sequence Similarity ◽  
Low Cost ◽  
High Specificity ◽  
Disease Diagnosis ◽  
Electrochemical Biosensors ◽  
High Sequence Similarity ◽  
Aberrant Expression ◽  
Specificity And Sensitivity ◽  
Different Types

MicroRNAs (miRNAs) are important non-coding, single-stranded RNAs possessing crucial regulating roles in human body. Therefore, miRNAs have received extensive attention from various disciplines as the aberrant expression of miRNAs are tightly related to different types of diseases. Furthermore, the exceptional stability of miRNAs has presented them as biomarker with high specificity and sensitivity. However, small size, high sequence similarity, low abundance of miRNAs impose difficulty in their detection. Hence, it is of utmost importance to develop accurate and sensitive method for miRNA biosensing. Electrochemical biosensors have been demonstrated as promising solution for miRNA detection as they are highly sensitive, facile, and low-cost with ease of miniaturization. The incorporation of nanomaterials to electrochemical biosensor offers excellent prospects for converting biological recognition events to electronic signal for the development of biosensing platform with desired sensing properties due to their unique properties. This review introduces the signal amplification strategies employed in miRNA electrochemical biosensor and presents the feasibility of different strategies. The recent advances in nanomaterial-based electrochemical biosensor for the detection of miRNA were also discussed and summarized based on different types of miRNAs, opening new approaches in biological analysis and early disease diagnosis. Lastly, the challenges and future prospects are discussed.

scholarly journals DNA-Metallodrugs Interactions Signaled by Electrochemical Biosensors: An Overview

2007 ◽  
Vol 2007 ◽  
pp. 1-11 ◽  
Author(s):  
Mauro Ravera ◽  
Graziana Bagni ◽  
Marco Mascini ◽  
Domenico Osella
Keyword(s):  
Electrostatic Interactions ◽  
Electrochemical Biosensor ◽  
Covalent Binding ◽  
Electrochemical Biosensors ◽  
Dna Biosensors ◽  
New Techniques ◽  
Guanine Oxidation ◽  
Technological Advances ◽  
Semiquantitative Evaluation ◽  
Biological Environment

The interaction of drugs with DNA is an important aspect in pharmacology. In recent years, many important technological advances have been made to develop new techniques to monitor biorecognition and biointeraction on solid devices. The interaction between DNA and drugs can cause chemical and conformational modifications and, thus, variation of the electrochemical properties of nucleobases. The propensity of a given compound to interact with DNA is measured as a function of the decrease of guanine oxidation signal on a DNA electrochemical biosensor. Covalent binding at N7 of guanine, electrostatic interactions, and intercalation are the events that this kind of biosensor can detect. In this context, the interaction between a panel of antitumoral Pt-, Ru-, and Ti-based metallodrugs with DNA immobilized on screen-printed electrodes has been studied. The DNA biosensors are used for semiquantitative evaluation of the analogous interaction occurring in the biological environment.

scholarly journals An electrochemical biosensor for prostate cancer biomarker detection using graphene oxide-gold nanostructures

2019 ◽  
Vol 19 (3) ◽  
pp. 206-216 ◽  
Author(s):  
Zahra Akbari jonous ◽  
Javad Shabani Shayeh ◽  
Fatemeh Yazdian ◽  
Amir Yadegari ◽  
Mohadeseh Hashemi ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Graphene Oxide ◽  
Electrochemical Biosensor ◽  
Cancer Biomarker ◽  
Gold Nanostructures ◽  
Biomarker Detection
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