A highly sensitive and adjustable colorimetric assay of hydrogen sulfide by signal amplification based on G-quadruplex-Cu2+ peroxidase mimetics

The Analyst ◽  
2020 ◽  
Vol 145 (8) ◽  
pp. 2995-3001 ◽  
Author(s):  
Yu Ma ◽  
Maotian Xu ◽  
Yongxiang Wang ◽  
Zi Liu ◽  
Baoxian Ye
Keyword(s):  
Hydrogen Sulfide ◽  
Signal Amplification ◽  
Colorimetric Assay ◽  
Highly Sensitive ◽  
G Quadruplex

This work reports the first example of a colorimetric H2S sensor constructed through G-quadruplex-Cu2+ (G4-Cu2+) peroxidase mimetics employing Cu2+ ions and G-rich DNA with signal amplification.

Gold nanoparticle-based exonuclease III signal amplification for highly sensitive colorimetric detection of folate receptor

Nanoscale ◽  
2014 ◽  
Vol 6 (6) ◽  
pp. 3055-3058 ◽  
Author(s):  
Xinjian Yang ◽  
Zhiqiang Gao
Keyword(s):  
Gold Nanoparticles ◽  
Small Molecule ◽  
Signal Amplification ◽  
Colorimetric Assay ◽  
Folate Receptor ◽  
Colorimetric Detection ◽  
Label Free ◽  
Exonuclease Iii ◽  
Highly Sensitive ◽  
Highly Sensitive Detection

By combining terminal protection of small molecule (folate)-capped DNA probes, exonuclease III signal amplification and gold nanoparticles, we developed a simple and label-free colorimetric assay for highly sensitive detection of folate receptor.

A G-quadruplex-based colorimetric assay of S1 nuclease activity and inhibition

2015 ◽  
Vol 7 (13) ◽  
pp. 5600-5605 ◽  
Author(s):  
Bingfang Shi ◽  
Yingfeng Qin ◽  
Mengjiao Huang ◽  
Jingjin Zhao ◽  
Yubin Su ◽  
...  
Keyword(s):  
Colorimetric Assay ◽  
Nuclease Activity ◽  
Label Free ◽  
Specific Detection ◽  
S1 Nuclease ◽  
Highly Sensitive ◽  
G Quadruplex

A label-free colorimetric assay based on the catalysis of G-quadruplex/hemin DNAzyme was developed for highly sensitive and specific detection of S1 nuclease activity and inhibition.

scholarly journals Electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform for highly sensitive detection of microRNA

2016 ◽  
Vol 52 (87) ◽  
pp. 12806-12809 ◽  
Author(s):  
Jian Li ◽  
Jingjin Zhao ◽  
Shuting Li ◽  
Liangliang Zhang ◽  
Yong Huang ◽  
...  
Keyword(s):  
Signal Amplification ◽  
Sensitive Detection ◽  
Highly Sensitive ◽  
G Quadruplex ◽  
Highly Sensitive Detection ◽  
Amplification Strategy ◽  
Electrophoresis Separation

An electrophoresis separation assisted G-quadruplex DNAzyme-based chemiluminescence signal amplification strategy on a microchip platform was developed for the detection of trace microRNA.

scholarly journals A dual colorimetric probe for rapid environmental monitoring of Hg2+ and As3+ using gold nanoparticles functionalized with d-penicillamine

RSC Advances ◽  
2021 ◽  
Vol 11 (10) ◽  
pp. 5456-5465
Author(s):  
Su-Jin Yoon ◽  
Yun-Sik Nam ◽  
Yeonhee Lee ◽  
In Hwan Oh ◽  
Kang-Bong Lee
Keyword(s):  
Gold Nanoparticles ◽  
Environmental Monitoring ◽  
Colorimetric Assay ◽  
Colorimetric Probe ◽  
Highly Sensitive ◽  
Dual Detection

A highly sensitive and selective colorimetric assay for the dual detection of Hg2+ and As3+ using gold nanoparticles (AuNPs) conjugated with d-penicillamine (DPL) was developed.

A highly sensitive electrochemical microRNA-21 biosensor based on intercalating methylene blue signal amplification and a highly dispersed gold nanoparticles/graphene/polypyrrole composite

The Analyst ◽  
2021 ◽  
Vol 146 (8) ◽  
pp. 2679-2688
Author(s):  
Chammari Pothipor ◽  
Noppadol Aroonyadet ◽  
Suwussa Bamrungsap ◽  
Jaroon Jakmunee ◽  
Kontad Ounnunkad
Keyword(s):  
Methylene Blue ◽  
Gold Nanoparticles ◽  
Signal Amplification ◽  
Electrochemical Biosensor ◽  
Highly Sensitive ◽  
Highly Dispersed ◽  
Polypyrrole Composite ◽  
Amplification Strategy ◽  
Dispersed Gold ◽  
Potential Tool

An ultrasensitive electrochemical biosensor based on a gold nanoparticles/graphene/polypyrrole composite modified electrode and a signal amplification strategy employing methylene blue is developed as a potential tool for the detection of miRNA-21.

scholarly journals Metal Nanoparticle and Quantum Dot Tags for Signal Amplification in Electrochemical Immunosensors for Biomarker Detection

Chemosensors ◽  
2021 ◽  
Vol 9 (4) ◽  
pp. 85
Author(s):  
Anton Popov ◽  
Benediktas Brasiunas ◽  
Asta Kausaite-Minkstimiene ◽  
Almira Ramanaviciene
Keyword(s):  
Signal Amplification ◽  
Electrochemical Immunosensor ◽  
Metal Nanoparticle ◽  
Biomarker Detection ◽  
Analytical Instruments ◽  
Electrochemical Immunosensors ◽  
Highly Sensitive ◽  
Recent Developments ◽  
Electrochemical Signal ◽  
Detection Of Biomarkers

With the increasing importance of healthcare and clinical diagnosis, as well as the growing demand for highly sensitive analytical instruments, immunosensors have received considerable attention. In this review, electrochemical immunosensor signal amplification strategies using metal nanoparticles (MNPs) and quantum dots (Qdots) as tags are overviewed, focusing on recent developments in the ultrasensitive detection of biomarkers. MNPs and Qdots can be used separately or in combination with other nanostructures, while performing the function of nanocarriers, electroactive labels, or catalysts. Thus, different functions of MNPs and Qdots as well as recent advances in electrochemical signal amplification are discussed. Additionally, the methods most often used for antibody immobilization on nanoparticles, immunoassay formats, and electrochemical methods for indirect biomarker detection are overviewed.

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