Design of salt-responsive and regenerative antibacterial polymer brushes with integrated bacterial resistance, killing, and release properties

2019 ◽  
Vol 7 (38) ◽  
pp. 5762-5774 ◽  
Author(s):  
Yang Wang ◽  
Jiahui Wu ◽  
Dong Zhang ◽  
Feng Chen ◽  
Ping Fan ◽  
...  
Keyword(s):  
Smart Materials ◽  
Polymer Brushes ◽  
Bacterial Resistance ◽  
Practical Applications ◽  
Fundamental Research

The development of smart materials and surfaces with multiple antibacterial actions is of great importance for both fundamental research and practical applications, but this has proved to be extremely challenging.

4D printing technology, modern era: A short review

2020 ◽  
pp. 92-111
Author(s):  
Khodadad Mostakim ◽  
Nahid Imtiaz Masuk ◽  
Md. Rakib Hasan ◽  
Md. Shafikul Islam
Keyword(s):  
Smart Materials ◽  
Computer Aided Design ◽  
Short Review ◽  
Stimuli Responsive ◽  
4D Printing ◽  
Space Applications ◽  
Printing Technology ◽  
Practical Applications ◽  
Biomedical Technologies ◽  
Novel Material

The advancement in 3D printing has led to the rapid growth of 4D printing technology. Adding time, as the fourth dimension, this technology ushered the potential of a massive evolution in fields of biomedical technologies, space applications, deployable structures, manufacturing industries, and so forth. This technology performs ingenious design, using smart materials to create advanced forms of the 3-D printed specimen. Improvements in Computer-aided design, additive manufacturing process, and material science engineering have ultimately favored the growth of 4-D printing innovation and revealed an effective method to gather complex 3-D structures. Contrast to all these developments, novel material is still a challenging sector. However, this short review illustrates the basic of 4D printing, summarizes the stimuli responsive materials properties, which have prominent role in the field of 4D technology. In addition, the practical applications are depicted and the potential prospect of this technology is put forward.

scholarly journals Heterodimer Formation of the Homodimeric ABC Transporter OpuA

2021 ◽  
Vol 22 (11) ◽  
pp. 5912
Author(s):  
Patricia Alvarez-Sieiro ◽  
Hendrik R. Sikkema ◽  
Bert Poolman
Keyword(s):  
Abc Transporter ◽  
Conformational Dynamics ◽  
Host Organism ◽  
Affinity Tag ◽  
Practical Applications ◽  
Fundamental Research ◽  
Protein Multimerization ◽  
Biochemical Analyses

Many proteins have a multimeric structure and are composed of two or more identical subunits. While this can be advantageous for the host organism, it can be a challenge when targeting specific residues in biochemical analyses. In vitro splitting and re-dimerization to circumvent this problem is a tedious process that requires stable proteins. We present an in vivo approach to transform homodimeric proteins into apparent heterodimers, which then can be purified using two-step affinity-tag purification. This opens the door to both practical applications such as smFRET to probe the conformational dynamics of homooligomeric proteins and fundamental research into the mechanism of protein multimerization, which is largely unexplored for membrane proteins. We show that expression conditions are key for the formation of heterodimers and that the order of the differential purification and reconstitution of the protein into nanodiscs is important for a functional ABC-transporter complex.

Nanoantibiotic Formulations to Combat Antibiotic Resistance - Old Wine in a New Bottle

2020 ◽  
Vol 13 (3) ◽  
pp. 174-183 ◽  
Author(s):  
Rachna Rana ◽  
Rajendra Awasthi ◽  
Bhupesh Sharma ◽  
Giriraj T. Kulkarni
Keyword(s):  
Antibiotic Resistance ◽  
Large Scale ◽  
Bacterial Resistance ◽  
Drug Loading ◽  
Treatment Success ◽  
Physicochemical Characteristics ◽  
Practical Applications ◽  
Pathological Conditions ◽  
New Frontier ◽  
Improved Stability

: Antibiotic resistance is becoming one of the major obstacles to treatment success in various pathological conditions. Development process of a new antimicrobial agent is slow and difficult, whereas bacterial resistance is decreasing the arsenal of existing antibiotics. Therefore, there is a need to develop novel antibiotic formulations to combat the resistance of existing antibiotics. Nanoparticles are investigated as novel antibiotic formulation, but are often inefficient in practical applications. Nanotechnology presents a new frontier to overcome the issue of antibiotic resistance through the development of functionalized particles. Balance of physicochemical characteristics such as small particle size and high drug loading capacity along with improved stability are the challenges associated with large scale manufacturing of nanoantibiotic formulations. In the last 1-2 decades, a gradual increase in patents on nanoantibiotic formulations has been noted to address the resistance issues of antibiotic. The aim of this review is to consolidate recently-investigated nanoantibiotic formulations to combat antibiotic resistance.

scholarly journals Damping in magnetorheological elastomers under compressive stress

2019 ◽  
Vol 254 ◽  
pp. 06002 ◽  
Author(s):  
Mateusz Kukla ◽  
Krzysztof Talaśka ◽  
Ireneusz Malujda
Keyword(s):  
Smart Materials ◽  
Hysteresis Loops ◽  
Machine Construction ◽  
Vibration Absorbers ◽  
Magnetorheological Elastomers ◽  
Practical Applications ◽  
Mechanical Hysteresis ◽  
Compressive Stresses ◽  
Active Vibration ◽  
Energy Absorbers

Magnetorheological elastomers are an important area of study in non-classical engineering materials. These are smart materials, in which some of the physical properties are dependent on the applied magnetic field. This unique property allows to suggest new, innovative practical applications. It is therefore relevant to carry out studies in the possible application of magnetorheological elastomers in machine construction. The present article presents the results of study regarding the properties of the discussed materials subject to compressive stresses. Particular attention is given to the observed growth of surface area of mechanical hysteresis loops, which is evidence of the possibility to change the damping properties of magnetorheological elastomers. This property can be utilized in the construction of different types of machines and devices. These mostly applies to energy absorbers such as active vibration absorbers.

A recurrent neural network–based model for predicting bending behavior of ionic polymer–metal composite actuators

2020 ◽  
Vol 31 (17) ◽  
pp. 1973-1985
Author(s):  
Hojat Zamyad ◽  
Nadia Naghavi ◽  
Reza Godaz ◽  
Reza Monsefi
Keyword(s):  
Smart Materials ◽  
Autoregressive Models ◽  
Metal Composite ◽  
Ionic Polymer Metal Composite ◽  
Ionic Polymer Metal Composites ◽  
Ionic Polymer ◽  
Practical Applications ◽  
Proposed Model ◽  
Polymer Metal ◽  
Application Potential

The high application potential of ionic polymer–metal composites has made the behavior identification of this group of smart materials an attractive area. So far, several models have been proposed to predict the bending of an ionic polymer–metal composite actuator, but these models have some weaknesses, the most important of them are the use of output data (in autoregressive models), high complexity to achieve a proper precision (in non-autoregressive models), and lack of compatibility with the behavioral nature of the material. In this article, we present a hybrid model of parallel non-autoregressive recurrent networks with internal memory cells to overcome existing weaknesses. The validation results on experimental data show that the proposed model has acceptable accuracy and flexibility. Moreover, simplicity and compatibility with the behavioral nature of the material promote using the proposed model in practical applications.

scholarly journals Mixed Polymer Brushes for “Smart” Surfaces

Polymers ◽  
2020 ◽  
Vol 12 (7) ◽  
pp. 1553 ◽  
Author(s):  
Mingxiao Li ◽  
Christian W. Pester
Keyword(s):  
Phase Behavior ◽  
Experimental Work ◽  
Smart Materials ◽  
Polymer Brushes ◽  
State Of The Art ◽  
Future Studies ◽  
Smart Surfaces ◽  
Synthetic Approaches ◽  
Novel Applications ◽  
External Stimuli

Mixed polymer brushes (MPBs) are composed of two or more disparate polymers covalently tethered to a substrate. The resulting phase segregated morphologies have been extensively studied as responsive “smart” materials, as they can be reversible tuned and switched by external stimuli. Both computational and experimental work has attempted to establish an understanding of the resulting nanostructures that vary as a function of many factors. This contribution highlights state-of-the-art MPBs studies, covering synthetic approaches, phase behavior, responsiveness to external stimuli as well as novel applications of MPBs. Current limitations are recognized and possible directions for future studies are identified.

scholarly journals Dynamical Manipulation of Surface Plasmon Polaritons

2019 ◽  
Vol 9 (16) ◽  
pp. 3297 ◽  
Author(s):  
Wang ◽  
Zhao ◽  
Li
Keyword(s):  
Electromagnetic Field ◽  
Metal Surface ◽  
Surface Plasmon ◽  
Surface Plasmon Polaritons ◽  
Wide Spectrum ◽  
Future Perspectives ◽  
Practical Applications ◽  
Fundamental Research ◽  
Dielectric Structures ◽  
Plasmon Polaritons

As the fundamental and promising branch of nanophotonics, surface plasmon polaritons (SPP) with the ability of manipulating the electromagnetic field on the subwavelength scale are of interest to a wide spectrum of scientists. Composed of metallic or dielectric structures whose shape and position are carefully engineered on the metal surface, traditional SPP devices are generally static and lack tunability. Dynamical manipulation of SPP is meaningful in both fundamental research and practical applications. In this article, the achievements in dynamical SPP excitation, SPP focusing, SPP vortex, and SPP nondiffracting beams are presented. The mechanisms of dynamical SPP devices are revealed and compared, and future perspectives are discussed.

scholarly journals Microdroplet-guided intercalation and deterministic delamination towards intelligent rolling origami

2019 ◽  
Vol 10 (1) ◽  
Author(s):  
Borui Xu ◽  
Xinyuan Zhang ◽  
Ziao Tian ◽  
Di Han ◽  
Xingce Fan ◽  
...  
Keyword(s):  
Low Cost ◽  
Rolling Direction ◽  
Three Dimensional ◽  
Van Der Waals Interaction ◽  
Creative Design ◽  
General Strategy ◽  
Practical Applications ◽  
On Demand ◽  
Vapor Sensing ◽  
Fundamental Research

Abstract Three-dimensional microstructures fabricated by origami, including folding, rolling and buckling, gain great interests in mechanics, optics and electronics. We propose a general strategy on on-demand and spontaneous rolling origami for artificial microstructures aiming at massive and intelligent production. Deposited nanomembranes are rolled-up in great amount triggered by the intercalation of tiny droplet, taking advantage of a creative design of van der Waals interaction with substrate. The rolling of nanomembranes delaminated by liquid permits a wide choice in materials as well as precise manipulation in rolling direction by controlling the motion of microdroplet, resulting in intelligent construction of rolling microstructures with designable geometries. Moreover, this liquid-triggered delamination phenomenon and constructed microstructures are demonstrated in the applications among vapor sensing, microresonators, micromotors, and microactuators. This investigation offers a simple, massive, low-cost, versatile and designable construction of rolling microstructures for fundamental research and practical applications.

Pattern Recognition of Impact in Passenger Car Bumper Using Smart Materials

2011 ◽  
Vol 462-463 ◽  
pp. 888-893
Author(s):  
Gao Ping Wang ◽  
Pan Zhou ◽  
Han Xin Chen ◽  
Jun Chen
Keyword(s):  
Neural Networks ◽  
Pattern Recognition ◽  
Smart Materials ◽  
Road Accidents ◽  
Passenger Cars ◽  
Passenger Car ◽  
Pendulum System ◽  
Fundamental Research ◽  
Impact Characteristics ◽  
The Impact

All over the world at present, injuries and fatalities from road accidents are a significant problem, especially occurred to pedestrians from passenger cars. Most of the fatal accidents between car and pedestrians prove deadly because of the head to hood impact. This paper aims to develop a bumper to avoid from passenger car’s fatal head impact for pedestrian protection, and most importantly, the impact of different objects with passenger car bumper needs to be recognized. Firstly, a pendulum system is constructed to perform the fundamental research which is concentrated on the response pattern of impact-object simulation tests, and we confirmed the application possibility for the method of discriminable pattern recognition whether impact-object is human-like or not by means of neural networks using smart PZT materials. Finally, the impact characteristics analyses can provide enough pattern recognition indices which can be developed and then used to recognize the impact information by two different neural networks.

scholarly journals Isoreticular zirconium-based metal–organic frameworks: discovering mechanical trends and elastic anomalies controlling chemical structure stability

2016 ◽  
Vol 18 (13) ◽  
pp. 9079-9087 ◽  
Author(s):  
Matthew R. Ryder ◽  
Bartolomeo Civalleri ◽  
Jin-Chong Tan
Keyword(s):  
Mechanical Properties ◽  
Chemical Structure ◽  
Metal Organic Frameworks ◽  
Structure Stability ◽  
Practical Applications ◽  
Open Framework ◽  
Metal Organic ◽  
Fundamental Research ◽  
Elastic Anomalies ◽  
Framework Compounds

Understanding the mechanical properties of MOFs is crucial not only to yield robust practical applications, but also to advance fundamental research underpinning flexibility of a myriad of open-framework compounds.

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