scholarly journals Additively manufactured porous metallic biomaterials

2019 ◽  
Vol 7 (26) ◽  
pp. 4088-4117 ◽  
Author(s):  
Amir A. Zadpoor

Additively manufactured (AM, =3D printed) porous metallic biomaterials with topologically ordered unit cells have created a lot of excitement and are currently receiving a lot of attention given their great potential for improving bone tissue regeneration and preventing implant-associated infections.

2021 ◽  
Vol 122 ◽  
pp. 111928
Author(s):  
Eduardo H. Backes ◽  
Emanuel M. Fernandes ◽  
Gabriela S. Diogo ◽  
Catarina F. Marques ◽  
Tiago H. Silva ◽  
...  

2021 ◽  
Vol 25 ◽  
pp. 101168
Author(s):  
Mohammad Mirkhalaf ◽  
Xiao Wang ◽  
Ali Entezari ◽  
Colin R. Dunstan ◽  
Xinquan Jiang ◽  
...  

Materials ◽  
2020 ◽  
Vol 13 (8) ◽  
pp. 1992
Author(s):  
Marianne Koolen ◽  
Saber Amin Yavari ◽  
Karel Lietaert ◽  
Ruben Wauthle ◽  
Amir A. Zadpoor ◽  
...  

Additively manufactured (AM) porous metallic biomaterials, in general, and AM porous titanium, in particular, have recently emerged as promising candidates for bone substitution. The porous design of such materials allows for mimicking the elastic mechanical properties of native bone tissue and showed to be effective in improving bone regeneration. It is, however, not clear what role the other mechanical properties of the bulk material such as ductility play in the performance of such biomaterials. In this study, we compared the bone tissue regeneration performance of AM porous biomaterials made from the commonly used titanium alloy Ti6Al4V-ELI with that of commercially pure titanium (CP-Ti). CP-Ti was selected because of its high ductility as compared to Ti6Al4V-ELI. Critical-sized (6 mm diameter) femoral defects in rats were treated with implants made from both Ti6Al4V-ELI and CP-Ti. Bone regeneration was assessed up to 11 weeks using micro-CT scanning. The regenerated bone volume was assessed ex vivo followed by histology and biomechanical testing to assess osseointegration of the implants. The bony defects treated with AM CP-Ti implants generally showed higher volumes of regenerated bone as compared to those treated with AM Ti6Al4V-ELI. The torsional strength of the two titanium groups were similar however, and both considerably lower than those measured for intact bony tissue. These findings show the importance of material type and ductility of the bulk material in the ability for bone tissue regeneration of AM porous biomaterials.


Biomaterials ◽  
2015 ◽  
Vol 37 ◽  
pp. 230-241 ◽  
Author(s):  
Falguni Pati ◽  
Tae-Ha Song ◽  
Girdhari Rijal ◽  
Jinah Jang ◽  
Sung Won Kim ◽  
...  

2016 ◽  
Vol 93 ◽  
pp. 1432-1445 ◽  
Author(s):  
Tiago R. Correia ◽  
Daniela R. Figueira ◽  
Kevin D. de Sá ◽  
Sónia P. Miguel ◽  
Ricardo G. Fradique ◽  
...  

2016 ◽  
Vol 07 (08) ◽  
pp. 430-452 ◽  
Author(s):  
Raquel Couto de Azevedo Gonçalves Mota ◽  
Emerson Oliveira da Silva ◽  
Felipe Fortes de Lima ◽  
Lívia Rodrigues de Menezes ◽  
Antonio Carlos Santos Thiele

2018 ◽  
Vol 165 ◽  
pp. 207-218 ◽  
Author(s):  
João C. Boga ◽  
Sónia P. Miguel ◽  
Duarte de Melo-Diogo ◽  
António G. Mendonça ◽  
Ricardo O. Louro ◽  
...  

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