Predicting the effect of chain-length mismatch on phase separation in noble metal nanoparticle monolayers with chemically mismatched ligands

Soft Matter ◽  
2019 ◽  
Vol 15 (22) ◽  
pp. 4498-4507 ◽  
Author(s):  
Steven N. Merz ◽  
Elise Hoover ◽  
Sergei A. Egorov ◽  
Kateri H. DuBay ◽  
David L. Green
Keyword(s):  
Drug Delivery ◽  
Monte Carlo ◽  
Phase Separation ◽  
Chain Length ◽  
Noble Metal ◽  
Monte Carlo Sampling ◽  
Mixed Ligand ◽  
Metal Nanoparticle ◽  
Monolayer Protected Nanoparticles

Enhanced Monte Carlo sampling can be used to predict the morphology of mixed ligand nanoparticle monolayers, providing a step forward in the design of monolayer protected nanoparticles for biosensing, drug delivery, and photonics.

Size-Induced Freezing Effect in Monte-Carlo Simulations of Phase Separation Kinetics in Nanoparticles

2008 ◽  
Vol 277 ◽  
pp. 167-175 ◽  
Author(s):  
A.S. Shirinyan ◽  
D.V. Lubyanskyy
Keyword(s):  
Monte Carlo ◽  
Phase Separation ◽  
Monte Carlo Simulations ◽  
Monte Carlo Sampling ◽  
Type Model ◽  
Two Dimensional ◽  
Vacancy Mechanism ◽  
Phase Separation Kinetics ◽  
Kinetics Of ◽  
Separation Kinetics

The separation kinetics in a binary nanoparticle is studied by means of two-dimensional Monte-Carlo sampling and Ising-type model, where the species exchange positions due to vacancy mechanism. The model is developed in case of a free nanoparticle with a coating shell. The kinetics is shown to depend on the size of a nanosystem. We demonstrate a distinct size-induced freezing effect on kinetics of separation.

scholarly journals The Effect of Ligands on Noble Metal Nanoparticles as Drug Delivery Systems to the Brain

2021 ◽  
Vol 10 (3) ◽  
Author(s):  
Shailee Shroff ◽  
Chad Curtis
Keyword(s):  
Drug Delivery ◽  
Metal Nanoparticles ◽  
Noble Metal ◽  
Invasive Surgery ◽  
Drug Delivery Systems ◽  
Cell Types ◽  
Delivery Systems ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
The Brain

metal nanoparticles have been used to address these diseases in the brain, however very few of these formulations have made it through clinical trials. This review will be discussing the role of noble metal nanoparticles as drug delivery systems specifically to the brain. A common problem many researchers and clinical physicians are facing problems because they are unable to access the brain without highly invasive surgery. Nanoparticles allow access to the brain without invasive surgery. Noble metal nanoparticles (NMNPs) are of particular interest because of their inherent characteristics which are amplified or reduced by ligands. The various ligands available change the method of transportation for a NMNPs traveling through the blood barrier. We will examine various ligands and their benefits and potential drawbacks. Furthermore, the optimal usage for each ligand and associated nanoparticle will also be examined. This review will go into detail about pure noble metal nanoparticle, glucose, PEG, CTAB, Transferrin, Anti-Microbial Peptide, and Chitosan as coatings. All of these are commonly used among researchers. The absorptivity into various cell types in the brain along with future implications will be examined.

scholarly journals Current Strategies for Noble Metal Nanoparticle Synthesis

2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Giyaullah Habibullah ◽  
Jitka Viktorova ◽  
Tomas Ruml
Keyword(s):  
Noble Metal ◽  
Noble Metals ◽  
Drug Carriers ◽  
Industrial Applications ◽  
Metal Nanoparticle ◽  
Noble Metal Nanoparticles ◽  
Synthesis Methods ◽  
Gold And Silver Nanoparticles ◽  
Diverse Range ◽  
The Past

AbstractNoble metals have played an integral part in human history for centuries; however, their integration with recent advances in nanotechnology and material sciences have provided new research opportunities in both academia and industry, which has resulted in a new array of advanced applications, including medical ones. Noble metal nanoparticles (NMNPs) have been of great importance in the field of biomedicine over the past few decades due to their importance in personalized healthcare and diagnostics. In particular, platinum, gold and silver nanoparticles have achieved the most dominant spot in the list, thanks to a very diverse range of industrial applications, including biomedical ones such as antimicrobial and antiviral agents, diagnostics, drug carriers and imaging probes. In particular, their superior resistance to extreme conditions of corrosion and oxidation is highly appreciated. Notably, in the past two decades there has been a tremendous advancement in the development of new strategies of more cost-effective and robust NMNP synthesis methods that provide materials with highly tunable physicochemical, optical and thermal properties, and biochemical functionalities. As a result, new advanced hybrid NMNPs with polymer, graphene, carbon nanotubes, quantum dots and core–shell systems have been developed with even more enhanced physicochemical characteristics that has led to exceptional diagnostic and therapeutic applications. In this review, we aim to summarize current advances in the synthesis of NMNPs (Au, Ag and Pt).

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