scholarly journals Functionalized DNA nanostructures as scaffolds for guided mineralization

2019 ◽  
Vol 10 (45) ◽  
pp. 10537-10542 ◽  
Author(s):  
Francesca Kim ◽  
Tong Chen ◽  
Trevor Burgess ◽  
Prakash Rasie ◽  
Tim Luca Selinger ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Dna Nanostructures ◽  
Polyaspartic Acid ◽  
Liquid Precursor

Nanopatterned DNA–polyaspartic acid (pAsp) conjugates guide the growth of calcium phosphate minerals in the polymer-induced liquid precursor (PILP) method.

scholarly journals REMINERALIZATION EFFECT OF POLYASPARTIC ACID IN THE POLYMER-INDUCED LIQUID PRECURSOR PROCESS ON THE INTRAFIBRILLAR DENTIN (SCANNING ELECTRON MICROSCOPE AND ENERGY DISPERSIVE X-RAY ANALYSIS)

2020 ◽  
pp. 45-48
Author(s):  
RIVANTI IRMADELA DEVINA ◽  
ADELINE CLARISSA ◽  
NILAKESUMA DJAUHARIE ◽  
KAMIZAR NAZAR ◽  
RATNA MEIDYAWATI
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
Energy Dispersive ◽  
Control Group ◽  
Polyaspartic Acid ◽  
Liquid Precursor ◽  
X Ray ◽  
Demineralized Dentin ◽  
Scanning Electron

Objective: This study aims to analyze remineralization that occurred in demineralized dentin following polyaspartic acid (pAsp) in PILP immersion.Methods: Sixteen dentin block samples were immersed in demineralized solution. The samples were divided into controls (no pAsp immersion) orpAsp immersion for 3, 7, or 14 days (n’s=4). The samples were evaluated using a scanning electron microscope (SEM) to observe morphology andenergy-dispersive X-ray (EDX) to observe calcium and phosphate levels.Results: SEM revealed that pAsp immersion resulted in significantly higher dentin remineralization compared to the control group. However, therewere no significant differences among 3, 7, and 14 days of immersion. EDX revealed that remineralization occurred by the deposition of calcium andphosphate ions.Conclusion: Including pAsp in the PILP process produced rapid remineralization of demineralized dentin.

Fluorescent polyaspartic acid with an enhanced inhibition performance against calcium phosphate

Desalination ◽  
2014 ◽  
Vol 345 ◽  
pp. 72-76 ◽  
Author(s):  
Jiuying Feng ◽  
Lijun Gao ◽  
Rizhen Wen ◽  
Yiyi Deng ◽  
Xiaojun Wu ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Polyaspartic Acid ◽  
Inhibition Performance

Hybrid calcium phosphate coatings with the addition of trace elements and polyaspartic acid by a low-thermal process

2011 ◽  
Vol 6 (3) ◽  
pp. 035002 ◽  
Author(s):  
Sanzhong Xu ◽  
Xianyan Yang ◽  
Xiaoyi Chen ◽  
Xiangjin Lin ◽  
Lei Zhang ◽  
...  
Keyword(s):  
Trace Elements ◽  
Calcium Phosphate ◽  
Thermal Process ◽  
Polyaspartic Acid ◽  
Phosphate Coatings ◽  
Calcium Phosphate Coatings

scholarly journals Osteoporotic Bone Recovery by a Highly Bone‐Inductive Calcium Phosphate Polymer‐Induced Liquid‐Precursor

2019 ◽  
Vol 6 (19) ◽  
pp. 1900683 ◽  
Author(s):  
Shasha Yao ◽  
Xianfeng Lin ◽  
Yifei Xu ◽  
Yangwu Chen ◽  
Pengcheng Qiu ◽  
...  
Keyword(s):  
Calcium Phosphate ◽  
Osteoporotic Bone ◽  
Liquid Precursor

scholarly journals EFFECT OF POLYMER-INDUCED LIQUID PRECURSOR PROCESS CONTAINING POLYASPARTIC ACID ON INTRAFIBRILLAR DENTIN REMINERALIZATION (MICRO-COMPUTED TOMOGRAPHY ANALYSIS)

2020 ◽  
pp. 41-44
Author(s):  
NORMA AVANTI ◽  
NILAKESUMA DJAUHARIE ◽  
ANGGRAINI MARGONO ◽  
RATNA MEIDYAWATI ◽  
CUT THYSA
Keyword(s):  
Acetate Buffer ◽  
Control Group ◽  
Micro Computed Tomography ◽  
Polyaspartic Acid ◽  
Liquid Precursor ◽  
Dentin Surface ◽  
Caries Treatment ◽  
Collagen Protein ◽  
The Mean ◽  
Demineralized Dentin

Objective: Caries treatment can be performed by minimal intervention, i.e., by removing the infected dentin and leaving the affected dentin and theninducing remineralization in the affected dentin. The affected dentin still consists of collagen cross bonds. Polymer-induced liquid precursor processis a guided tissue remineralization method that aims to remineralize intrafibrillar and extrafibrillar dentin by adding polymers that are similar tonon-collagen protein. One of the non-collagen protein analog materials is polyaspartic acid. The aim of this study was to evaluate the remineralizationof dentin on the demineralized dentin surface after immersed in remineralization solutions containing polyaspartic acid as a non-collagen proteinanalog.Methods: Human premolar teeth extracted for orthodontic purposes were divided into four groups, namely, one control and three treatment groups.Teeth in the control group were immersed only in the demineralization solution containing acetate buffer (pH 5.0, 66 h). Teeth in the three treatmentgroups were immersed in acetate buffer (pH 5.0, 66 h) and then continue to immersed in the remineralization solution containing polyaspartic acidfor 3, 7, and 14 days. Remineralization was evaluated by micro-CT.Results: Remineralization appeared on the demineralized dentin surface, characterized by an increase in the grayscale index, after immersion inthe remineralization solution containing polyaspartic acid. Significant differences were observed in the mean grayscale index values among the fourgroups.Conclusion: Polyaspartic acid has the potential to induce dentin remineralization.

scholarly journals EFFECTS OF POLYASPARTIC ACID ON REMINERALIZATION OF INTRAFIBRILLAR DENTIN AND SIZE OF HYDROXYAPATITE CRYSTALS

2020 ◽  
pp. 73-76
Author(s):  
WAVIYATUL AHDI ◽  
NILAKESUMA DJAUHARIE ◽  
RATNA MEIDYAWATI ◽  
IKHWAN MUSLIM
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Control Group ◽  
Polyaspartic Acid ◽  
Liquid Precursor ◽  
X Ray ◽  
Treatment Groups ◽  
Transmission Electron ◽  
Demineralized Dentin ◽  
Hydroxyapatite Crystals

Objective: The objective of this study was to analyze the intrafibrillar remineralization process and the size of hydroxyapatite crystals formed.Methods: The samples were divided into four groups. The control group was immersed in a demineralization solution, whereas the remaining threetreatment groups were immersed in a remineralization solution containing polyaspartic acid for 3, 7, or 14 days. The effect of polyaspartic acid onintrafibrillar remineralization during the polymer-induced liquid-precursor (PILP) process was evaluated using transmission electron microscopy,and the size of hydroxyapatite crystals was examined through X-ray diffraction.Results: Significant differences were detected in the intrafibrillar remineralization between the treatment groups (subjected to remineralization for3, 7, and 14 days) and the demineralized dentin control group. However, no significant differences were detected in the size of hydroxyapatite crystalsbetween the control and the treatment groups.Conclusion: Our data suggest that polyaspartic acid enables intrafibrillar remineralization during the PILP process.

Controlled thin layer calcium phosphate mineralization on DNA nanostructures

2021 ◽  
Author(s):  
Meizhou Zhang ◽  
Shanshan Wu ◽  
Longjie Li ◽  
Jun Li ◽  
Yuzhou Wu
Keyword(s):  
Calcium Phosphate ◽  
Thin Layer ◽  
Dna Nanostructures ◽  
Phosphate Mineralization
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