scholarly journals Mesoporous cerium oxide-coated upconversion nanoparticles for tumor-responsive chemo-photodynamic therapy and bioimaging

2019 ◽  
Vol 10 (37) ◽  
pp. 8618-8633 ◽  
Author(s):  
Tao Jia ◽  
Jiating Xu ◽  
Shuming Dong ◽  
Fei He ◽  
Chongna Zhong ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Irradiation ◽  
Cerium Oxide ◽  
Oxide Shell ◽  
Upconversion Nanoparticles ◽  
Imaging Guidance ◽  
Multiple Imaging

A hollow structured biophotocatalyst comprising an UCNP core and mesoporous cerium oxide shell was constructed to realize oxygen self-efficient photodynamic therapy upon 980 nm laser irradiation under multiple imaging guidance.

A nanosystem loaded with perfluorohexane and rose bengal coupled upconversion nanoparticles for multimodal imaging and synergetic chemo-photodynamic therapy of cancer

2020 ◽  
Vol 8 (9) ◽  
pp. 2488-2506 ◽  
Author(s):  
Hai-yan Wang ◽  
Li Hou ◽  
Hai-liang Li ◽  
Xu Wang ◽  
Yang Cao ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Laser Irradiation ◽  
Rose Bengal ◽  
Multimodal Imaging ◽  
Upconversion Nanoparticles ◽  
Photodynamic Therapy Of Cancer ◽  
Targeted Release

A novel nanosystem (FURH-PFH-NPs) combined with LIFU and laser irradiation realized multimodal imaging, targeted release of HCPT, UCNPs-RB and synergetic chemo-photodynamic therapy of cancer.

Construction of a near-infrared responsive upconversion nanoplatform against hypoxic tumors via NO-enhanced photodynamic therapy

Nanoscale ◽  
2020 ◽  
Vol 12 (14) ◽  
pp. 7875-7887 ◽  
Author(s):  
Ying Lan ◽  
Xiaohui Zhu ◽  
Ming Tang ◽  
Yihan Wu ◽  
Jing Zhang ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Near Infrared ◽  
Upconversion Nanoparticles

A near-infrared (NIR) activated theranostic nanoplatform based on upconversion nanoparticles (UCNPs) is developed in order to overcome the hypoxia-associated resistance in photodynamic therapy by photo-release of NO upon NIR illumination.

MET-targeted NIR II luminescence diagnosis and up-conversion guided photodynamic therapy for triple-negative breast cancer based on the lanthanide nanoprobes

Nanoscale ◽  
2021 ◽  
Author(s):  
Yanxing Wang ◽  
Miao Feng ◽  
Bi Lin ◽  
Xiangrong Peng ◽  
Zhan Wang ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Photodynamic Therapy ◽  
Triple Negative Breast Cancer ◽  
Triple Negative ◽  
Upconversion Nanoparticles

In this research, degradable peptide-modified upconversion nanoparticles (ZUPEA) were designed for NIR II imaging and uponversion luminescence (UCL) guided photodynamic therapy (PDT) to triple-negative breast cancer (TNBC). The ultra-small rare...

Effect of photodynamic therapy and ErCrYSGG laser irradiation on the push-out bond strength between fiber post and root dentin

2019 ◽  
Vol 27 ◽  
pp. 415-418 ◽  
Author(s):  
Faisal Abdullah Alonaizan ◽  
Yasser F. AlFawaz ◽  
Abdulaziz Alsahhaf ◽  
Raneem S. Alofi ◽  
Khulud Abdulrahman Al-Aali ◽  
...  
Keyword(s):  
Photodynamic Therapy ◽  
Bond Strength ◽  
Laser Irradiation ◽  
Fiber Post ◽  
Root Dentin ◽  
Push Out

scholarly journals Manganese-Doped Cerium Oxide Nanocomposite Induced Photodynamic Therapy in MCF-7 Cancer Cells and Antibacterial Activity

2019 ◽  
Vol 2019 ◽  
pp. 1-13 ◽  
Author(s):  
M. Atif ◽  
Seemab Iqbal ◽  
M. Fakhar-E-Alam ◽  
M. Ismail ◽  
Qaisar Mansoor ◽  
...  
Keyword(s):  
Antibacterial Activity ◽  
Photodynamic Therapy ◽  
Cell Viability ◽  
Cerium Oxide ◽  
Bacterial Infections ◽  
Reactive Oxygen Species Generation ◽  
Doped Ceria ◽  
Bacterial Strains ◽  
Chemical Route ◽  
Mcf 7

In this experimental approach, we explored the structures, morphologies, phototoxicities, and antibacterial activities of undoped and Mn-doped ceria nanocomposite materials, MnxCe1−xO2. The MnxCe1−xO2 nanocomposites were synthesized by employing a soft chemical route. Our prime focus was on the influence of different factors, both physical and chemical, i.e., the concentration of manganese in the product, size of the nanocomposite, drug dose, and incubation time, on the bacterial strains. Different bacterial strains were selected as experimental biological models of the antibacterial activity of the manganese-doped cerium oxide nanocomposite. In addition to the photodynamic response, the adenocarcinoma cell line (MCF-7) was also studied. Based on cell viability losses and bacterial inhibition analyses, the precise mechanisms of apoptosis or necrosis of 5-ALA/PpIX-exposed MCF-7 cells under 630 nm red lights and under dark conditions were elucidated. It was observed that the undoped nanocomposites had lower cytotoxicities and inhibitions compared with those of the doped nanocomposites towards pathogens. The antibacterial activity and effectiveness for photodynamic therapy were enhanced in the presence of the manganese-doped ceria nanocomposite, which could be attributed to the correlation of the maximum reactive oxygen species generation for targeted toxicity and maximum antioxidant property in bacteria growth inhibition. The optimized cell viability dose and doping concentration will be beneficial for treating cancer and bacterial infections in the future.

Feasibility of transgingival laser irradiation for antimicrobial photodynamic therapy

2019 ◽  
Vol 28 ◽  
pp. 75-79 ◽  
Author(s):  
Johannes-Simon Wenzler ◽  
Sarah Böcher ◽  
Roland Frankenberger ◽  
Andreas Braun
Keyword(s):  
Photodynamic Therapy ◽  
Laser Irradiation ◽  
Antimicrobial Photodynamic Therapy

Photosensitizer coated upconversion nanoparticles for triggering reactive oxygen species under 980 nm near-infrared excitation

2019 ◽  
Vol 7 (46) ◽  
pp. 7306-7313 ◽  
Author(s):  
Jinhua Wu ◽  
Shanshan Du ◽  
Yuhua Wang
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Rare Earth ◽  
Near Infrared ◽  
Reactive Oxygen ◽  
Great Promise ◽  
Upconversion Nanoparticles ◽  
Oxygen Species ◽  
Infrared Excitation

Rare-earth-based upconversion nanotechnology has recently shown great promise for photodynamic therapy (PDT).

scholarly journals Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics

Theranostics ◽  
2013 ◽  
Vol 3 (5) ◽  
pp. 317-330 ◽  
Author(s):  
Chao Wang ◽  
Liang Cheng ◽  
Zhuang Liu
Keyword(s):  
Photodynamic Therapy ◽  
Cancer Therapeutics ◽  
Upconversion Nanoparticles
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