scholarly journals A visible-light mediated three-component radical process using dithiocarbamate anion catalysis

2019 ◽  
Vol 10 (21) ◽  
pp. 5484-5488 ◽  
Author(s):  
Sara Cuadros ◽  
Matthew A. Horwitz ◽  
Bertrand Schweitzer-Chaput ◽  
Paolo Melchiorre
Keyword(s):  
Visible Light ◽  
Catalytic Mechanism ◽  
Radical Process ◽  
Biologically Relevant

A three-component radical process is reported that, by coupling alkyl chlorides, maleimides, and heteroaromatic fragments, installs multiple biologically relevant heterocycles within complex cascade products. This method, which generates radicals via an SN2-based photochemical catalytic mechanism, activates substrates incompatible with or inert to classical radical-generating strategies.

Visible-light activated metal catalyst-free vicinal diazidation of olefins with sulfonium iodate(i) species

2019 ◽  
Vol 55 (19) ◽  
pp. 2833-2836 ◽  
Author(s):  
Thurpu Raghavender Reddy ◽  
Dodla Sivanageswara Rao ◽  
Sudhir Kashyap
Keyword(s):  
Visible Light ◽  
Late Stage ◽  
Metal Catalyst ◽  
Radical Process ◽  
Biologically Relevant ◽  
Catalyst Free

An unprecedented visible-light inspired selective radical azidation of unactivated and diverse substituted vinylarenes with sulfonium iodate reagent has been realized. The intrinsic radical process triggered by light tolerated several synthetically useful functionalities enabling two new carbon-hetero bonds which display distinctive late-stage applications to biologically relevant scaffolds.

Visible-Light-Induced Nitrogen-Centered Radical Process for the Construction of 3-Acylcoumarins

2021 ◽  
Author(s):  
Quan Zhou ◽  
Fang-Ting Xiong ◽  
Pu Chen ◽  
Biquan Xiong ◽  
Kewen Tang ◽  
...  
Keyword(s):  
Visible Light ◽  
Cyclization Reactions ◽  
Radical Process

A nitrogen-centered radical-mediated strategy is described to synthesize functionalized 3-acylcoumarins. This process is enabled by visible-light-induced acylation/cyclization reactions of alkynoates with various acyl oxime compounds in acetonitrile. The difunctionalization of...

scholarly journals Visible-Light Photoswitching of G-Quadruplex Ligand Binding Mode Allows Reversible Control of G-Tetrad Structure

2020 ◽  
Author(s):  
Michael O'Hagan ◽  
Javier Ramos Soriano ◽  
Susanta Haldar ◽  
Juan Carlos Morales ◽  
Adrian Mulholland ◽  
...  
Keyword(s):  
Ligand Binding ◽  
Visible Light ◽  
Uv Light ◽  
Binding Mode ◽  
High Energy ◽  
Light Sources ◽  
Biologically Relevant ◽  
G Quadruplex ◽  
Potential Applications ◽  
Robust Regulation

<div><p>Photoresponsive ligands for G-quadruplex oligonucleotides (G4) offer exciting opportunities for the reversible regulation of these assemblies with potential applications in biological chemistry and responsive nanotechnology. However, achieving the robust regulation of G4 ligand activity with low-energy visible light sources that are easily accessible and compatible with biological systems remains a significant challenge to realizing these applications. Herein, we report the G4-binding properties of a photoresponsive dithienylethene (DTE). We demonstrate the first example of G4-specific acceleration of the photoswitching kinetics of a small molecule and the visible-light mediated switching of the G4 ligand binding mode in physiologically-relevant conditions, which in turn allows control over the G4 tetrad structure of telomeric G4 in potassium buffer. The process is fully reversible and avoids the need for high-energy UV light. This affords an efficient, practical and biologically-relevant means of control that may be applied in the generation of new responsive G4/ligand supramolecular systems.</p></div><br>

Visible-Light-Mediated, Chemo- and Stereoselective Radical Process for the Synthesis of C-Glycoamino Acids

2019 ◽  
Vol 21 (9) ◽  
pp. 3086-3092 ◽  
Author(s):  
Peng Ji ◽  
Yueteng Zhang ◽  
Yongyi Wei ◽  
He Huang ◽  
Wenbo Hu ◽  
...  
Keyword(s):  
Visible Light ◽  
Radical Process

The photocatalytic activity and degradation mechanism of methylene blue over copper(ii) tetra(4-carboxyphenyl) porphyrin sensitized TiO2under visible light irradiation

RSC Advances ◽  
2014 ◽  
Vol 4 (55) ◽  
pp. 28978-28986 ◽  
Author(s):  
Huigang Wang ◽  
Dongmei Zhou ◽  
Shaosong Shen ◽  
Junmin Wan ◽  
Xuming Zheng ◽  
...  
Keyword(s):  
Methylene Blue ◽  
Photocatalytic Activity ◽  
Visible Light ◽  
Visible Light Irradiation ◽  
Catalytic Mechanism ◽  
Degradation Mechanism ◽  
Light Irradiation ◽  
Electronic Relaxation ◽  
Relaxation Dynamics

Copper(ii)tetra(4-carboxyphenyl) porphyrin were chemically sensitized on TiO2, its electronic relaxation dynamics and the visible-light induced catalytic mechanism are discussed.

Synthesis of trifluoromethylthioesters from aldehydes via a visible light-promoted radical process

2020 ◽  
Vol 18 (30) ◽  
pp. 5918-5926 ◽  
Author(s):  
Meng-Yue Wang ◽  
Xue-Qing Zhu ◽  
Xing-Long Zhang ◽  
Rui-Li Guo ◽  
Qiong Jia ◽  
...  
Keyword(s):  
Visible Light ◽  
Radical Process

An unprecedented visible light-promoted approach to the synthesis of trifluoromethylthioesters from aldehydes has been developed.

Interfacial effect of the nanostructured Ag2S/Co3O4 and its catalytic mechanism for the dye photodegradation under visible light

2016 ◽  
Vol 362 ◽  
pp. 498-505 ◽  
Author(s):  
X.P. Qiu ◽  
J.S. Yu ◽  
H.M. Xu ◽  
W.X. Chen ◽  
W. Hu ◽  
...  
Keyword(s):  
Visible Light ◽  
Catalytic Mechanism ◽  
Interfacial Effect

scholarly journals Visible-light Mediated Ring Opening Reaction of Alkylidenecyclopropanes for the Generation of Homopropargyl Radical

2021 ◽  
Author(s):  
Xiao-Yu Zhang ◽  
Chao Ning ◽  
Ben Mao ◽  
Yin Wei ◽  
Min Shi
Keyword(s):  
Molecular Structure ◽  
Visible Light ◽  
Ring Opening ◽  
Mechanistic Studies ◽  
Radical Process ◽  
Ring Opening Reaction ◽  
Long Time ◽  
Radical Clock

Classical cyclopropylcarbinyl radical clock reactions have been widely applied to conduct the mechanistic studies on probing radical process for a long time; however, alkylidenecyclopropanes, which have a similar molecular structure...

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