Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide

Xiaojun Xu; Shu Xing; Mengjia Xu; Pan Fu; Tingting Gao; Xiaokang Zhang; Yang Zhao; Chao Zhao

doi:10.1039/c9ra06758b

Highly sensitive and specific screening of EGFR mutation using a PNA microarray-based fluorometric assay based on rolling circle amplification and graphene oxide

RSC Advances ◽

10.1039/c9ra06758b ◽

2019 ◽

Vol 9 (66) ◽

pp. 38298-38308 ◽

Cited By ~ 1

Author(s):

Xiaojun Xu ◽

Shu Xing ◽

Mengjia Xu ◽

Pan Fu ◽

Tingting Gao ◽

...

Keyword(s):

Graphene Oxide ◽

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Egfr Mutation ◽

Rolling Circle Amplification ◽

Specific Detection ◽

Fluorometric Method ◽

Rolling Circle ◽

Highly Sensitive ◽

Detection Probe

A facile peptide nucleic acid microarray-based fluorometric method was developed for sensitive and specific detection of EGFR mutation by using rolling circle amplification, graphene oxide, and a fluorescently-labeled detection probe.

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A novel chemiluminescence immunoassay for highly sensitive and specific detection of protein using rolling circle amplification and the multiplex binding system

Sensors and Actuators B Chemical ◽

10.1016/j.snb.2015.06.063 ◽

2015 ◽

Vol 221 ◽

pp. 328-333 ◽

Cited By ~ 11

Author(s):

Heng Chen ◽

Shaoyan Wu ◽

Fang Dong ◽

Wei Cheng ◽

Qifu Li ◽

...

Keyword(s):

Rolling Circle Amplification ◽

Specific Detection ◽

Chemiluminescence Immunoassay ◽

Rolling Circle ◽

Binding System ◽

Highly Sensitive

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Colorimetric Sensing by Using Allosteric-DNAzyme-Coupled Rolling Circle Amplification and a Peptide Nucleic Acid-Organic Dye Probe

Angewandte Chemie International Edition ◽

10.1002/anie.200805966 ◽

2009 ◽

Vol 48 (19) ◽

pp. 3512-3515 ◽

Cited By ~ 104

Author(s):

M. Monsur Ali ◽

Yingfu Li

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Rolling Circle Amplification ◽

Organic Dye ◽

Colorimetric Sensing ◽

Rolling Circle ◽

Dye Probe

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Direct, sequence-specific detection of dsDNA based on peptide nucleic acid and graphene oxide without requiring denaturation

Biosensors and Bioelectronics ◽

10.1016/j.bios.2014.06.028 ◽

2014 ◽

Vol 62 ◽

pp. 140-144 ◽

Cited By ~ 26

Author(s):

Jieon Lee ◽

Il-Soo Park ◽

Euihan Jung ◽

Younghoon Lee ◽

Dal-Hee Min

Keyword(s):

Graphene Oxide ◽

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Direct Sequence ◽

Specific Detection

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An electrochemiluminescence biosensor for Kras mutations based on locked nucleic acid functionalized DNA walkers and hyperbranched rolling circle amplification

Chemical Communications ◽

10.1039/c7cc00009j ◽

2017 ◽

Vol 53 (20) ◽

pp. 2910-2913 ◽

Cited By ~ 51

Author(s):

Ying Zhang ◽

Lixu Wang ◽

Fang Luo ◽

Bin Qiu ◽

Longhua Guo ◽

...

Keyword(s):

Nucleic Acid ◽

Rolling Circle Amplification ◽

Locked Nucleic Acid ◽

Specific Detection ◽

Kras Mutations ◽

Rolling Circle ◽

Dna Walkers ◽

Mutant Genes

Herein, an electrochemiluminescence (ECL) biosensor for ultrasensitive and specific detection of Kras mutant genes has been developed.

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Strategies for highly sensitive biomarker detection by Rolling Circle Amplification of signals from nucleic acid composed sensors

Integrative Biology ◽

10.1039/c1ib00049g ◽

2011 ◽

Vol 3 (10) ◽

pp. 982 ◽

Cited By ~ 39

Author(s):

Magnus Stougaard ◽

Sissel Juul ◽

Felicie F. Andersen ◽

Birgitta R. Knudsen

Keyword(s):

Nucleic Acid ◽

Rolling Circle Amplification ◽

Biomarker Detection ◽

Rolling Circle ◽

Highly Sensitive

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Colorimetric Sensing by Using Allosteric-DNAzyme-Coupled Rolling Circle Amplification and a Peptide Nucleic Acid-Organic Dye Probe

Angewandte Chemie ◽

10.1002/ange.200805966 ◽

2009 ◽

Vol 121 (19) ◽

pp. 3564-3567 ◽

Cited By ~ 39

Author(s):

M. Monsur Ali ◽

Yingfu Li

Keyword(s):

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Rolling Circle Amplification ◽

Organic Dye ◽

Colorimetric Sensing ◽

Rolling Circle ◽

Dye Probe

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Isothermal Detection of Canine Blood Parasite (Ehrlichia canis) Utilizing Recombinase Polymerase Amplification Coupled with Graphene Oxide Quenching-Based Pyrrolidinyl Peptide Nucleic Acid

Bioconjugate Chemistry ◽

10.1021/acs.bioconjchem.0c00639 ◽

2021 ◽

Author(s):

Phanomsak Yukhet ◽

Kittisak Buddhachat ◽

Tirayut Vilaivan ◽

Chaturong Suparpprom

Keyword(s):

Graphene Oxide ◽

Nucleic Acid ◽

Peptide Nucleic Acid ◽

Blood Parasite ◽

Ehrlichia Canis ◽

Recombinase Polymerase Amplification

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The analysis of proteins and small molecules based on sterically tunable nucleic acid hyperbranched rolling circle amplification

Biosensors and Bioelectronics ◽

10.1016/j.bios.2016.12.016 ◽

2017 ◽

Vol 91 ◽

pp. 136-142 ◽

Cited By ~ 16

Author(s):

Hai Shi ◽

Xiaoxia Mao ◽

Xiaoxia Chen ◽

Zihan Wang ◽

Keming Wang ◽

...

Keyword(s):

Nucleic Acid ◽

Small Molecules ◽

Rolling Circle Amplification ◽

Rolling Circle

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A DNA nanomachine based on rolling circle amplification-bridged two-stage exonuclease III-assisted recycling strategy for label-free multi-amplified biosensing of nucleic acid

Analytica Chimica Acta ◽

10.1016/j.aca.2014.11.035 ◽

2015 ◽

Vol 856 ◽

pp. 103-109 ◽

Cited By ~ 20

Author(s):

Qingwang Xue ◽

Yanqin Lv ◽

Hui Cui ◽

Xiaohong Gu ◽

Shuqiu Zhang ◽

...

Keyword(s):

Nucleic Acid ◽

Rolling Circle Amplification ◽

Label Free ◽

Two Stage ◽

Exonuclease Iii ◽

Rolling Circle ◽

Dna Nanomachine

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Target-responsive dumbbell probe-mediated rolling circle amplification strategy for highly sensitive Hg2+ detection

RSC Advances ◽

10.1039/c4ra02266a ◽

2014 ◽

Vol 4 (51) ◽

pp. 27091-27097 ◽

Cited By ~ 4

Author(s):

Qingwang Xue ◽

Yanqin Lv ◽

Yuanfu Zhang ◽

Shuling Xu ◽

Qiaoli Yue ◽

...

Keyword(s):

Rolling Circle Amplification ◽

Selective Detection ◽

Label Free ◽

Rolling Circle ◽

Fluorescent Sensing ◽

Highly Sensitive ◽

Mercuric Ions ◽

Amplification Strategy

A novel label-free amplified fluorescent sensing scheme based on target-responsive dumbbell probe-mediated rolling circle amplification (D-RCA) has been developed for sensitive and selective detection of mercuric ions.

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