scholarly journals Preparative separation of structural isomeric pentacyclic triterpene oleanolic acid and ursolic acid from natural products by pH-zone-refining countercurrent chromatography

RSC Advances ◽  
2019 ◽  
Vol 9 (66) ◽  
pp. 38860-38866
Author(s):  
Chaoyue Wang ◽  
Xiang Wang ◽  
Shanshan Zhao ◽  
Wenyu Sun ◽  
Shengqiang Tong

pH-zone-refining countercurrent chromatography was investigated in preparative separation of oleanolic acid and ursolic acid from three different natural products, Aralia chinensis, apple peels and Eriobotrya japonica Thunb.

MedChemComm ◽  
2019 ◽  
Vol 10 (8) ◽  
pp. 1370-1378 ◽  
Author(s):  
Chun-Mei Liu ◽  
Jia-Yan Huang ◽  
Li-Xin Sheng ◽  
Xiao-An Wen ◽  
Ke-Guang Cheng

Due to the obvious adverse effects of 5-fluorouracil and considering the diverse biological activities of pentacyclic triterpenes, twelve pentacyclic triterpene-5-fluorouracil conjugates were synthesized and their antitumor activities were evaluated.


Molecules ◽  
2014 ◽  
Vol 19 (7) ◽  
pp. 8752-8761 ◽  
Author(s):  
Qinghai Zhang ◽  
Xikai Shu ◽  
Feng Jing ◽  
Xiao Wang ◽  
Changhu Lin ◽  
...  

Author(s):  
NARGEES SHAIKH ◽  
GAURANG SAWANT ◽  
NIKHIL DIXIT

Natural products derived from plants have been used for decades in traditional medicine. Many classes of compounds exist in plants such as saponins, alkaloids, anti-oxidants, etc. Pentacyclic triterpenes are also one of the compounds occurring in plants. In this class Ursolic acid is a well-recognized compound that is available from various sources like seeds as well as fruits and possess many types of activities and is a bright contender for developing novel treatment approaches for treating diseases.


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