scholarly journals Preparation and characterization of peptide modified ultrasmall superparamagnetic iron oxides used as tumor targeting MRI contrast agent

RSC Advances ◽  
2019 ◽  
Vol 9 (34) ◽  
pp. 19397-19407 ◽  
Author(s):  
Jie Yin ◽  
Guangfu Yin ◽  
Ximing Pu ◽  
Zhongbing Huang ◽  
Dajin Yao

As desirable contrast agents for magnetic resonance imaging (MRI), ultrasmall superparamagnetic iron oxides (USPIOs) modified with targeting ligands are considered to be the most effective strategies to achieve better imaging contrast at lower dose.

RSC Advances ◽  
2020 ◽  
Vol 10 (23) ◽  
pp. 13872-13878 ◽  
Author(s):  
Yining Yan ◽  
Lei Ding ◽  
Lin Liu ◽  
Murad M. A. Abualrejal ◽  
Hongda Chen ◽  
...  

Hyaluronic acid functionalized NaGdF4 nanodots were synthesized and evaluated as an active tumor-targeting magnetic resonance imaging (MRI) contrast agent.


2017 ◽  
Vol 8 (34) ◽  
pp. 5157-5166 ◽  
Author(s):  
A. V. Fuchs ◽  
A. P. Bapat ◽  
G. J. Cowin ◽  
K. J. Thurecht

A switchable polymeric 19F magnetic resonance imaging (MRI) contrast agent was synthesised whereby the transverse (T2) relaxation times increased as a therapeutic was released from a hyperbranched polymer (HBP) scaffold.


Nanoscale ◽  
2015 ◽  
Vol 7 (20) ◽  
pp. 9174-9184 ◽  
Author(s):  
Jeotikanta Mohapatra ◽  
Arijit Mitra ◽  
Himanshu Tyagi ◽  
D. Bahadur ◽  
M. Aslam

An efficient magnetic resonance imaging (MRI) contrast agent with a highR2relaxivity value is achieved by controlling the shape of iron oxide to rod like morphology with a length of 30–70 nm and diameter of 4–12 nm.


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