scholarly journals Sensitive detection of methylated DNA and methyltransferase activity based on the lighting up of FAM-labeled DNA quenched fluorescence by gold nanoparticles

RSC Advances ◽  
2019 ◽  
Vol 9 (21) ◽  
pp. 12063-12069 ◽  
Author(s):  
Mohammad Ali Karimi ◽  
Mehdi Dadmehr ◽  
Morteza Hosseini ◽  
Behnaz Korouzhdehi ◽  
Fatemeh Oroojalian

A novel method for detection of DNA methylation based on fluorescence recovery of FAM labeled DNA/Au NPs was introduced.

The Analyst ◽  
2016 ◽  
Vol 141 (2) ◽  
pp. 579-584 ◽  
Author(s):  
Weiting Zhang ◽  
Xiaolong Zu ◽  
Yanling Song ◽  
Zhi Zhu ◽  
Chaoyong James Yang

Abnormal DNA methylation patterns caused by altered DNA methyltransferase (MTase) activity are closely associated with cancer. Herein, using DNA adenine methylation methyltransferase (Dam MTase) as a model analyte, we designed an allosteric molecular beacon (aMB) for sensitive detection of Dam MTase activity.


RSC Advances ◽  
2015 ◽  
Vol 5 (42) ◽  
pp. 33468-33477 ◽  
Author(s):  
Vaibhavkumar N. Mehta ◽  
Rakesh Kumar Singhal ◽  
Suresh Kumar Kailasa

Schematic representation for the colorimetric sensing of Al3+ion using PCA-DTC-Au NPs as a probe.


RSC Advances ◽  
2014 ◽  
Vol 4 (101) ◽  
pp. 57709-57714 ◽  
Author(s):  
Yuan Zhao ◽  
Yaodong Luo ◽  
Tongtong Li ◽  
Qijun Song

A simple gold nanoparticles–Ir complex driven electrochemiluminescence aptasensors was fabricated for the sensitive detection of fumonisin B1.


2010 ◽  
Vol 82 (1) ◽  
pp. 229-233 ◽  
Author(s):  
Tao Liu ◽  
Jing Zhao ◽  
Dongmei Zhang ◽  
Genxi Li

RSC Advances ◽  
2019 ◽  
Vol 9 (33) ◽  
pp. 18728-18733
Author(s):  
Jinjin Yin ◽  
Jiuchao Wang ◽  
Xiyue Yang ◽  
Tao Wu ◽  
Huashan Wang ◽  
...  

In this work, a facile and sensitive colorimetric sensor for Hg2+ ions based on poly (adenine)-mediated DNA-functionalized gold nanoparticles (Au NPs) is reported.


2017 ◽  
Vol 184 (6) ◽  
pp. 1855-1862 ◽  
Author(s):  
Hongyu Zhao ◽  
Shuhui Bian ◽  
Yongfeng Yang ◽  
Xuping Wu

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